(17 nodes) FCERI mediated NF-kB activation network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Tak1/mapkkk7	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (190 aa)
	LOC100185384	ubiquitin-60S ribosomal protein L40. (128 aa)
	H2Y3S9_CIOIN	RPN2_C domain-containing protein. (79 aa)
	LOC100185957	Mucosa-associated lymphoid tissue lymphoma translocation protein 1-like isoform X1. (624 aa)
	H2Y0N7_CIOIN	Pkinase_Tyr domain-containing protein. (196 aa)
	LOC113474176	kxDL motif-containing protein 1-like. (139 aa)
	Q1RPY5_CIOIN	Zinc finger protein. (579 aa)
	LOC100179989	PPM-type phosphatase domain-containing protein. (490 aa)
	F6VJQ1_CIOIN	Uncharacterized protein. (347 aa)
	F6VM15_CIOIN	RanBP2-type domain-containing protein. (339 aa)
	F6TER2_CIOIN	Protein kinase domain-containing protein. (206 aa)
	Q4H3C1_CIOIN	IkappaB kinase. (172 aa)
	LOC100186680	Caspase recruitment domain-containing protein 11-like isoform X1. (418 aa)
	betaTrCP	Beta-transducin repeat-containing HOMOLOGUE protein. (621 aa)
	LOC100176760	Proteasome subunit alpha type. (253 aa)
	F6ZJN8_CIOIN	Uncharacterized protein. (381 aa)
	r27a	R27a protein isoform X1. (155 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6TER2_CIOIN	F6VJQ1_CIOIN	ENSCINP00000023589	ENSCINP00000026820	Protein kinase domain-containing protein.	Uncharacterized protein.	0.419
F6TER2_CIOIN	F6VM15_CIOIN	ENSCINP00000023589	ENSCINP00000026560	Protein kinase domain-containing protein.	RanBP2-type domain-containing protein.	0.797
F6TER2_CIOIN	F6ZJN8_CIOIN	ENSCINP00000023589	ENSCINP00000015598	Protein kinase domain-containing protein.	Uncharacterized protein.	0.419
F6TER2_CIOIN	LOC100179989	ENSCINP00000023589	ENSCINP00000026995	Protein kinase domain-containing protein.	PPM-type phosphatase domain-containing protein.	0.811
F6TER2_CIOIN	LOC100185384	ENSCINP00000023589	ENSCINP00000010307	Protein kinase domain-containing protein.	ubiquitin-60S ribosomal protein L40.	0.471
F6TER2_CIOIN	LOC100185957	ENSCINP00000023589	ENSCINP00000036544	Protein kinase domain-containing protein.	Mucosa-associated lymphoid tissue lymphoma translocation protein 1-like isoform X1.	0.433
F6TER2_CIOIN	LOC100186680	ENSCINP00000023589	ENSCINP00000020343	Protein kinase domain-containing protein.	Caspase recruitment domain-containing protein 11-like isoform X1.	0.465
F6TER2_CIOIN	Q1RPY5_CIOIN	ENSCINP00000023589	ENSCINP00000030768	Protein kinase domain-containing protein.	Zinc finger protein.	0.799
F6TER2_CIOIN	Q4H3C1_CIOIN	ENSCINP00000023589	ENSCINP00000021745	Protein kinase domain-containing protein.	IkappaB kinase.	0.636
F6TER2_CIOIN	r27a	ENSCINP00000023589	ENSCINP00000012037	Protein kinase domain-containing protein.	R27a protein isoform X1.	0.463
F6VJQ1_CIOIN	F6TER2_CIOIN	ENSCINP00000026820	ENSCINP00000023589	Uncharacterized protein.	Protein kinase domain-containing protein.	0.419
F6VJQ1_CIOIN	F6VM15_CIOIN	ENSCINP00000026820	ENSCINP00000026560	Uncharacterized protein.	RanBP2-type domain-containing protein.	0.692
F6VJQ1_CIOIN	H2Y0N7_CIOIN	ENSCINP00000026820	ENSCINP00000035471	Uncharacterized protein.	Pkinase_Tyr domain-containing protein.	0.419
F6VJQ1_CIOIN	H2Y3S9_CIOIN	ENSCINP00000026820	ENSCINP00000036564	Uncharacterized protein.	RPN2_C domain-containing protein.	0.686
F6VJQ1_CIOIN	LOC100176760	ENSCINP00000026820	ENSCINP00000017839	Uncharacterized protein.	Proteasome subunit alpha type.	0.733
F6VJQ1_CIOIN	LOC100185384	ENSCINP00000026820	ENSCINP00000010307	Uncharacterized protein.	ubiquitin-60S ribosomal protein L40.	0.923
F6VJQ1_CIOIN	LOC113474176	ENSCINP00000026820	ENSCINP00000031397	Uncharacterized protein.	kxDL motif-containing protein 1-like.	0.461
F6VJQ1_CIOIN	Q1RPY5_CIOIN	ENSCINP00000026820	ENSCINP00000030768	Uncharacterized protein.	Zinc finger protein.	0.855
F6VJQ1_CIOIN	Q4H3C1_CIOIN	ENSCINP00000026820	ENSCINP00000021745	Uncharacterized protein.	IkappaB kinase.	0.507
F6VJQ1_CIOIN	Tak1/mapkkk7	ENSCINP00000026820	ENSCINP00000011860	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.419