(15 nodes) G-protein beta:gamma signalling network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	F6QTX2_CIOIN	Uncharacterized protein. (800 aa)
	H2XP47_CIOIN	G protein gamma domain-containing protein. (68 aa)
	F6Y556_CIOIN	MFS_1_like domain-containing protein. (223 aa)
	F6Y572_CIOIN	MFS_1_like domain-containing protein. (268 aa)
	cdc42	Uncharacterized protein. (95 aa)
	F6QIH1_CIOIN	MFS domain-containing protein. (448 aa)
	LOC100182745	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. (347 aa)
	LOC100180112	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1106 aa)
	F6WVT9_CIOIN	Protein kinase domain-containing protein. (505 aa)
	F6S4F7_CIOIN	Non-specific serine/threonine protein kinase. (512 aa)
	F6QZH0_CIOIN	Protein kinase domain-containing protein. (459 aa)
	LOC100185742	Guanine nucleotide-binding protein subunit beta-5. (376 aa)
	F6YSN1_CIOIN	MFS domain-containing protein. (308 aa)
	H2XXW5_CIOIN	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
	H2XQR3_CIOIN	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (67 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6QTX2_CIOIN	LOC100180112	ENSCINP00000016882	ENSCINP00000014240	Uncharacterized protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.762
F6QZH0_CIOIN	F6S4F7_CIOIN	ENSCINP00000016849	ENSCINP00000016461	Protein kinase domain-containing protein.	Non-specific serine/threonine protein kinase.	0.843
F6QZH0_CIOIN	LOC100180112	ENSCINP00000016849	ENSCINP00000014240	Protein kinase domain-containing protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.536
F6S4F7_CIOIN	F6QZH0_CIOIN	ENSCINP00000016461	ENSCINP00000016849	Non-specific serine/threonine protein kinase.	Protein kinase domain-containing protein.	0.843
F6S4F7_CIOIN	F6WVT9_CIOIN	ENSCINP00000016461	ENSCINP00000014529	Non-specific serine/threonine protein kinase.	Protein kinase domain-containing protein.	0.983
F6S4F7_CIOIN	LOC100180112	ENSCINP00000016461	ENSCINP00000014240	Non-specific serine/threonine protein kinase.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.774
F6S4F7_CIOIN	LOC100182745	ENSCINP00000016461	ENSCINP00000007802	Non-specific serine/threonine protein kinase.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1.	0.434
F6S4F7_CIOIN	LOC100185742	ENSCINP00000016461	ENSCINP00000035188	Non-specific serine/threonine protein kinase.	Guanine nucleotide-binding protein subunit beta-5.	0.471
F6S4F7_CIOIN	cdc42	ENSCINP00000016461	ENSCINP00000001500	Non-specific serine/threonine protein kinase.	Uncharacterized protein.	0.560
F6WVT9_CIOIN	F6S4F7_CIOIN	ENSCINP00000014529	ENSCINP00000016461	Protein kinase domain-containing protein.	Non-specific serine/threonine protein kinase.	0.983
F6WVT9_CIOIN	LOC100180112	ENSCINP00000014529	ENSCINP00000014240	Protein kinase domain-containing protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.536
H2XP47_CIOIN	H2XQR3_CIOIN	ENSCINP00000031430	ENSCINP00000031997	G protein gamma domain-containing protein.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.540
H2XP47_CIOIN	H2XXW5_CIOIN	ENSCINP00000031430	ENSCINP00000034499	G protein gamma domain-containing protein.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.540
H2XP47_CIOIN	LOC100182745	ENSCINP00000031430	ENSCINP00000007802	G protein gamma domain-containing protein.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1.	0.868
H2XP47_CIOIN	LOC100185742	ENSCINP00000031430	ENSCINP00000035188	G protein gamma domain-containing protein.	Guanine nucleotide-binding protein subunit beta-5.	0.868
H2XQR3_CIOIN	H2XP47_CIOIN	ENSCINP00000031997	ENSCINP00000031430	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	G protein gamma domain-containing protein.	0.540
H2XQR3_CIOIN	H2XXW5_CIOIN	ENSCINP00000031997	ENSCINP00000034499	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.540
H2XQR3_CIOIN	LOC100182745	ENSCINP00000031997	ENSCINP00000007802	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1.	0.904
H2XQR3_CIOIN	LOC100185742	ENSCINP00000031997	ENSCINP00000035188	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Guanine nucleotide-binding protein subunit beta-5.	0.904
H2XXW5_CIOIN	H2XP47_CIOIN	ENSCINP00000034499	ENSCINP00000031430	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	G protein gamma domain-containing protein.	0.540