STRINGSTRING
H2XRC3_CIOIN H2XRC3_CIOIN F6WHL2_CIOIN F6WHL2_CIOIN F6WGY1_CIOIN F6WGY1_CIOIN Zf(cchc/grf)-1 Zf(cchc/grf)-1 LOC100177452 LOC100177452 F6RJ65_CIOIN F6RJ65_CIOIN F7B012_CIOIN F7B012_CIOIN LOC100184966 LOC100184966 Sir2-d Sir2-d F6VD75_CIOIN F6VD75_CIOIN F6RZ99_CIOIN F6RZ99_CIOIN F6RYY5_CIOIN F6RYY5_CIOIN F6T6X1_CIOIN F6T6X1_CIOIN F6XG24_CIOIN F6XG24_CIOIN LOC100179894 LOC100179894 F6W2K0_CIOIN F6W2K0_CIOIN LOC100184693 LOC100184693 LOC100181411 LOC100181411 F6QHZ5_CIOIN F6QHZ5_CIOIN zf(parp)-2 zf(parp)-2 F6XMX2_CIOIN F6XMX2_CIOIN LOC100178968 LOC100178968 LOC100184240 LOC100184240 F6Z4B6_CIOIN F6Z4B6_CIOIN LOC100185732 LOC100185732 F6YH93_CIOIN F6YH93_CIOIN swi/snf swi/snf F6TV58_CIOIN F6TV58_CIOIN LOC100187071 LOC100187071 F7ATF3_CIOIN F7ATF3_CIOIN zf(c2h2)-102 zf(c2h2)-102 F6WPB7_CIOIN F6WPB7_CIOIN F6PLM3_CIOIN F6PLM3_CIOIN LOC100175771 LOC100175771 LOC100181422 LOC100181422 LOC100178929 LOC100178929 F6WMB2_CIOIN F6WMB2_CIOIN LOC100185652 LOC100185652 LOC100185384 LOC100185384 F6SK60_CIOIN F6SK60_CIOIN F7B4V9_CIOIN F7B4V9_CIOIN LOC100179869 LOC100179869 F7BF26_CIOIN F7BF26_CIOIN F6USX3_CIOIN F6USX3_CIOIN LOC100181635 LOC100181635 F6ZQY6_CIOIN F6ZQY6_CIOIN r27a r27a LOC100184859 LOC100184859 F7ANZ8_CIOIN F7ANZ8_CIOIN F6ZJN8_CIOIN F6ZJN8_CIOIN F6Z8G0_CIOIN F6Z8G0_CIOIN F6T453_CIOIN F6T453_CIOIN F6UD40_CIOIN F6UD40_CIOIN LOC100182716 LOC100182716 F6WC79_CIOIN F6WC79_CIOIN F6WBW9_CIOIN F6WBW9_CIOIN F6Q9T0_CIOIN F6Q9T0_CIOIN F6PLC9_CIOIN F6PLC9_CIOIN LOC100182844 LOC100182844 F6UX10_CIOIN F6UX10_CIOIN LOC108949301 LOC108949301 F6TK51_CIOIN F6TK51_CIOIN F6WUQ7_CIOIN F6WUQ7_CIOIN Ci-ZF(PARP)-3 Ci-ZF(PARP)-3 F6QH43_CIOIN F6QH43_CIOIN F7BPT5_CIOIN F7BPT5_CIOIN LOC100185848 LOC100185848 F7A9P4_CIOIN F7A9P4_CIOIN F6RAS4_CIOIN F6RAS4_CIOIN F6Q2W2_CIOIN F6Q2W2_CIOIN F6VJQ1_CIOIN F6VJQ1_CIOIN F6TYB0_CIOIN F6TYB0_CIOIN F6X4N7_CIOIN F6X4N7_CIOIN F6YN96_CIOIN F6YN96_CIOIN LOC100177967 LOC100177967 zf(ring)-23 zf(ring)-23 H2XJH5_CIOIN H2XJH5_CIOIN LOC113474468 LOC113474468 H2XJN2_CIOIN H2XJN2_CIOIN H2XKT2_CIOIN H2XKT2_CIOIN H2XL15_CIOIN H2XL15_CIOIN H2XL69_CIOIN H2XL69_CIOIN H2XLY1_CIOIN H2XLY1_CIOIN H2XMB6_CIOIN H2XMB6_CIOIN LOC100180075 LOC100180075 H2XN24_CIOIN H2XN24_CIOIN H2XNP0_CIOIN H2XNP0_CIOIN H2XNU2_CIOIN H2XNU2_CIOIN H2XNV1_CIOIN H2XNV1_CIOIN LOC113474176 LOC113474176 H2XQC3_CIOIN H2XQC3_CIOIN H2XQL7_CIOIN H2XQL7_CIOIN H2XR02_CIOIN H2XR02_CIOIN cbf-2 cbf-2 LOC100181925 LOC100181925 H2XV49_CIOIN H2XV49_CIOIN H2XWS4_CIOIN H2XWS4_CIOIN LOC100182514 LOC100182514 H2XXE2_CIOIN H2XXE2_CIOIN H2XXR3_CIOIN H2XXR3_CIOIN LOC100177765 LOC100177765 LOC100179616 LOC100179616 LOC100179093 LOC100179093 LOC100175682 LOC100175682 H2Y1A0_CIOIN H2Y1A0_CIOIN H2Y1I3_CIOIN H2Y1I3_CIOIN LOC100175013 LOC100175013 H2Y2T2_CIOIN H2Y2T2_CIOIN H2Y2Y0_CIOIN H2Y2Y0_CIOIN H2Y3C6_CIOIN H2Y3C6_CIOIN H2Y3G4_CIOIN H2Y3G4_CIOIN H2Y3M4_CIOIN H2Y3M4_CIOIN LOC100183893 LOC100183893
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
H2XRC3_CIOINUncharacterized protein. (224 aa)
F6WHL2_CIOINUmuC domain-containing protein. (288 aa)
F6WGY1_CIOINStructure-specific endonuclease subunit SLX1 homolog; Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA; Belongs to the SLX1 family. (246 aa)
Zf(cchc/grf)-1DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (456 aa)
LOC100177452Uncharacterized protein. (603 aa)
F6RJ65_CIOINUncharacterized protein; Belongs to the PI3/PI4-kinase family. (268 aa)
F7B012_CIOINUBIQUITIN_CONJUGAT_2 domain-containing protein. (130 aa)
LOC100184966Histone H2B-like; Belongs to the histone H2B family. (121 aa)
Sir2-dDeacetylase sirtuin-type domain-containing protein. (91 aa)
F6VD75_CIOINUncharacterized protein. (553 aa)
F6RZ99_CIOINZinc-hook domain-containing protein. (477 aa)
F6RYY5_CIOINAAA_23 domain-containing protein. (400 aa)
F6T6X1_CIOINTudor domain-containing protein. (431 aa)
F6XG24_CIOINUncharacterized protein. (180 aa)
LOC100179894Werner syndrome ATP-dependent helicase homolog isoform X1. (1194 aa)
F6W2K0_CIOINDUF1767 domain-containing protein. (486 aa)
LOC100184693Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (262 aa)
LOC100181411Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa)
F6QHZ5_CIOINFHA domain-containing protein. (234 aa)
zf(parp)-2DNA ligase. (859 aa)
F6XMX2_CIOINUncharacterized protein. (279 aa)
LOC100178968DNA polymerase. (1064 aa)
LOC100184240Ubiquitin-conjugating enzyme E2 35-like isoform X2; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
F6Z4B6_CIOINUncharacterized protein. (758 aa)
LOC100185732DRMBL domain-containing protein. (277 aa)
F6YH93_CIOINUncharacterized protein. (1111 aa)
swi/snfCi-SWI/SNF protein. (1003 aa)
F6TV58_CIOINUncharacterized protein. (147 aa)
LOC100187071Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (187 aa)
F7ATF3_CIOINzf-4CXXC_R1 domain-containing protein. (286 aa)
zf(c2h2)-102ATP-dependent DNA helicase II subunit 2; Single-stranded DNA-dependent ATP-dependent helicase. (706 aa)
F6WPB7_CIOINBRCC36_C domain-containing protein. (108 aa)
F6PLM3_CIOINBromo domain-containing protein. (295 aa)
LOC100175771Cell cycle checkpoint control protein; Belongs to the rad9 family. (424 aa)
LOC100181422Replication factor C subunit 2-like. (336 aa)
LOC100178929Serine/threonine-protein phosphatase. (307 aa)
F6WMB2_CIOINUncharacterized protein. (524 aa)
LOC100185652Mre11_DNA_bind domain-containing protein; Belongs to the MRE11/RAD32 family. (530 aa)
LOC100185384ubiquitin-60S ribosomal protein L40. (128 aa)
F6SK60_CIOINUncharacterized protein. (372 aa)
F7B4V9_CIOINReplication factor C subunit 1. (866 aa)
LOC100179869Checkpoint protein; Belongs to the HUS1 family. (286 aa)
F7BF26_CIOINUncharacterized protein. (449 aa)
F6USX3_CIOINUncharacterized protein. (983 aa)
LOC100181635AAA domain-containing protein. (356 aa)
F6ZQY6_CIOINPoly [ADP-ribose] polymerase. (537 aa)
r27aR27a protein isoform X1. (155 aa)
LOC100184859Replication factor C subunit 3-like. (355 aa)
F7ANZ8_CIOINUncharacterized protein. (293 aa)
F6ZJN8_CIOINUncharacterized protein. (381 aa)
F6Z8G0_CIOINProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (454 aa)
F6T453_CIOINUncharacterized protein; Belongs to the cyclin family. (430 aa)
F6UD40_CIOINEyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (434 aa)
LOC100182716Flap endonuclease GEN homolog 1. (709 aa)
F6WC79_CIOINUncharacterized protein. (347 aa)
F6WBW9_CIOINDNA_pol_E_B domain-containing protein. (165 aa)
F6Q9T0_CIOINUncharacterized protein. (231 aa)
F6PLC9_CIOINTIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (128 aa)
LOC100182844Importin subunit alpha; Belongs to the importin alpha family. (529 aa)
F6UX10_CIOINDNA_LIGASE_A3 domain-containing protein; Belongs to the ATP-dependent DNA ligase family. (655 aa)
LOC108949301BRCT domain-containing protein. (292 aa)
F6TK51_CIOINUncharacterized protein. (350 aa)
F6WUQ7_CIOINDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2157 aa)
Ci-ZF(PARP)-3Zinc finger protein. (565 aa)
F6QH43_CIOINRING-type domain-containing protein. (309 aa)
F7BPT5_CIOINCBFD_NFYB_HMF domain-containing protein. (75 aa)
LOC100185848Deacetylase sirtuin-type domain-containing protein. (357 aa)
F7A9P4_CIOINNUC194 domain-containing protein. (726 aa)
F6RAS4_CIOINUncharacterized protein. (405 aa)
F6Q2W2_CIOINANK_REP_REGION domain-containing protein. (223 aa)
F6VJQ1_CIOINUncharacterized protein. (347 aa)
F6TYB0_CIOINBRCT domain-containing protein. (246 aa)
F6X4N7_CIOINSerine/threonine-protein phosphatase. (324 aa)
F6YN96_CIOIN3'-5' exonuclease domain-containing protein. (573 aa)
LOC100177967BTB domain-containing protein. (531 aa)
zf(ring)-23RING-type domain-containing protein. (319 aa)
H2XJH5_CIOINANK_REP_REGION domain-containing protein. (95 aa)
LOC113474468Replication protein A 14 kDa subunit-like. (118 aa)
H2XJN2_CIOINRECA_2 domain-containing protein. (255 aa)
H2XKT2_CIOIN3'-5' exonuclease domain-containing protein. (128 aa)
H2XL15_CIOINSAE2 domain-containing protein. (153 aa)
H2XL69_CIOINUncharacterized protein. (458 aa)
H2XLY1_CIOINUncharacterized protein. (292 aa)
H2XMB6_CIOINUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (163 aa)
LOC100180075DNA polymerase delta subunit 4-like isoform X1. (107 aa)
H2XN24_CIOINPI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family. (158 aa)
H2XNP0_CIOINUncharacterized protein. (243 aa)
H2XNU2_CIOINUncharacterized protein. (214 aa)
H2XNV1_CIOINPoly [ADP-ribose] polymerase. (659 aa)
LOC113474176kxDL motif-containing protein 1-like. (139 aa)
H2XQC3_CIOINDNA_pol_B_thumb domain-containing protein. (110 aa)
H2XQL7_CIOINUncharacterized protein. (295 aa)
H2XR02_CIOINDUF1767 domain-containing protein. (229 aa)
cbf-2Transcription factor CBF/NF-Y/archaeal histone -2. (156 aa)
LOC100181925DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents; Belongs to the RecA family. RAD51 subfamily. (328 aa)
H2XV49_CIOINFAT domain-containing protein. (219 aa)
H2XWS4_CIOINUncharacterized protein. (179 aa)
LOC100182514Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (607 aa)
H2XXE2_CIOINANK_REP_REGION domain-containing protein. (116 aa)
H2XXR3_CIOINPoly [ADP-ribose] polymerase. (472 aa)
LOC100177765UCH_1 domain-containing protein. (237 aa)
LOC100179616UmuC domain-containing protein. (440 aa)
LOC100179093AAA domain-containing protein. (329 aa)
LOC100175682DNA polymerase delta subunit 3. (469 aa)
H2Y1A0_CIOINUncharacterized protein. (345 aa)
H2Y1I3_CIOINUncharacterized protein. (231 aa)
LOC100175013Uncharacterized protein. (379 aa)
H2Y2T2_CIOINFAT domain-containing protein. (235 aa)
H2Y2Y0_CIOINANK_REP_REGION domain-containing protein. (215 aa)
H2Y3C6_CIOINUncharacterized protein; Belongs to the PI3/PI4-kinase family. (540 aa)
H2Y3G4_CIOINBRCT domain-containing protein. (335 aa)
H2Y3M4_CIOINUncharacterized protein. (185 aa)
LOC100183893Uncharacterized protein. (480 aa)
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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