75 items (Ciona intestinalis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC100175682	DNA polymerase delta subunit 3. (469 aa)
	LOC100179093	AAA domain-containing protein. (329 aa)
	LOC100179616	UmuC domain-containing protein. (440 aa)
	H2XZ54_CIOIN	RPOLD domain-containing protein. (286 aa)
	H2XXZ3_CIOIN	Uncharacterized protein. (870 aa)
	LOC100182514	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (607 aa)
	ENSCINP00000033882	annotation not available (91 aa)
	LOC100184165	General transcription factor IIH subunit 3-like. (309 aa)
	H2XVJ2_CIOIN	Uncharacterized protein. (141 aa)
	H2XUA5_CIOIN	Uncharacterized protein. (917 aa)
	LOC101242260	DNA-directed RNA polymerases I, II, and III subunit RPABC4. (79 aa)
	cbf-2	Transcription factor CBF/NF-Y/archaeal histone -2. (156 aa)
	LOC113474176	kxDL motif-containing protein 1-like. (139 aa)
	LOC100182516	RING-box protein 1. (104 aa)
	LOC100180075	DNA polymerase delta subunit 4-like isoform X1. (107 aa)
	LOC100181341	DNA-directed RNA polymerase II subunit RPB11-a isoform X1. (117 aa)
	LOC113474468	Replication protein A 14 kDa subunit-like. (118 aa)
	H2XJG6_CIOIN	Uncharacterized protein. (211 aa)
	LOC100177967	BTB domain-containing protein. (531 aa)
	F6TY64_CIOIN	Uncharacterized protein. (388 aa)
	F6VJQ1_CIOIN	Uncharacterized protein. (347 aa)
	F6YY15_CIOIN	ERCC4 domain-containing protein. (826 aa)
	F7BPT5_CIOIN	CBFD_NFYB_HMF domain-containing protein. (75 aa)
	LOC100182035	COP9 signalosome complex subunit 8-like. (190 aa)
	F6XIG6_CIOIN	RPOL4c domain-containing protein. (133 aa)
	LOC100178283	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (152 aa)
	F6PIR1_CIOIN	USP domain-containing protein; Belongs to the peptidase C19 family. (151 aa)
	F6Y5Q3_CIOIN	RPOLD domain-containing protein. (151 aa)
	F6WUQ7_CIOIN	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2157 aa)
	LOC100176942	COP9 signalosome complex subunit 1. (475 aa)
	ckn1	Cockayne syndrome 1 homolog. (403 aa)
	F6WBW9_CIOIN	DNA_pol_E_B domain-containing protein. (165 aa)
	LOC100177051	PCI domain-containing protein. (442 aa)
	zf(ring)-55	Zinc finger protein. (323 aa)
	LOC100177272	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1814 aa)
	F6RRF2_CIOIN	MPN domain-containing protein. (318 aa)
	F6Q587_CIOIN	Uncharacterized protein. (86 aa)
	F6Q4Z2_CIOIN	Uncharacterized protein. (276 aa)
	Zf(c2h2)-114	General transcription factor IIH subunit. (395 aa)
	LOC100175879	CULLIN_2 domain-containing protein; Belongs to the cullin family. (614 aa)
	LOC100179498	DNA repair protein complementing XP-A cells homolog. (279 aa)
	LOC100184693	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (262 aa)
	zf(parp)-2	DNA ligase. (859 aa)
	LOC100178968	DNA polymerase. (1064 aa)
	LOC100183592	COP9 signalosome complex subunit 4. (409 aa)
	LOC100183594	General transcription and DNA repair factor IIH helicase subunit XPB. (794 aa)
	LOC113474384	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (245 aa)
	F6ZP18_CIOIN	Uncharacterized protein. (1328 aa)
	F6YGJ7_CIOIN	Uncharacterized protein; Belongs to the peptidase C19 family. (1099 aa)
	F6RMT1_CIOIN	Uncharacterized protein. (551 aa)
	LOC100181422	Replication factor C subunit 2-like. (336 aa)
	LOC100177778	DNA-directed RNA polymerase II subunit RPB7. (172 aa)
	LOC100185384	ubiquitin-60S ribosomal protein L40. (128 aa)
	LOC113474404	COP9 signalosome complex subunit 7a-like. (283 aa)
	LOC100177816	cyclin-H; Belongs to the cyclin family. (329 aa)
	F7B4V9_CIOIN	Replication factor C subunit 1. (866 aa)
	F7BF26_CIOIN	Uncharacterized protein. (449 aa)
	LOC100183293	Transcription elongation factor A protein 1. (298 aa)
	LOC100181635	AAA domain-containing protein. (356 aa)
	F6Y1Y0_CIOIN	Uncharacterized protein. (217 aa)
	F6Y1W8_CIOIN	Uncharacterized protein. (261 aa)
	r27a	R27a protein isoform X1. (155 aa)
	F6RKQ2_CIOIN	Uncharacterized protein. (437 aa)
	F6QR00_CIOIN	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1183 aa)
	F6QLM7_CIOIN	MPN domain-containing protein. (345 aa)
	LOC100177099	Protein NRDE2 homolog. (935 aa)
	LOC100184859	Replication factor C subunit 3-like. (355 aa)
	F6SBF1_CIOIN	Uncharacterized protein. (852 aa)
	LOC100176493	AAA domain-containing protein. (844 aa)
	F6S7U3_CIOIN	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (182 aa)
	F6S7T3_CIOIN	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (238 aa)
	F6RZ45_CIOIN	Uncharacterized protein. (591 aa)
	F7ANR5_CIOIN	CPSF_A domain-containing protein. (1145 aa)
	F6ZJN8_CIOIN	Uncharacterized protein. (381 aa)
	LOC100183893	Uncharacterized protein. (480 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCINP00000033882	F6QLM7_CIOIN	ENSCINP00000033882	ENSCINP00000013258	annotation not available	MPN domain-containing protein.	0.978
ENSCINP00000033882	F6QR00_CIOIN	ENSCINP00000033882	ENSCINP00000013245	annotation not available	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.584
ENSCINP00000033882	F6RMT1_CIOIN	ENSCINP00000033882	ENSCINP00000009626	annotation not available	Uncharacterized protein.	0.538
ENSCINP00000033882	F6RRF2_CIOIN	ENSCINP00000033882	ENSCINP00000001153	annotation not available	MPN domain-containing protein.	0.972
ENSCINP00000033882	F6VJQ1_CIOIN	ENSCINP00000033882	ENSCINP00000026820	annotation not available	Uncharacterized protein.	0.459
ENSCINP00000033882	F6Y1W8_CIOIN	ENSCINP00000033882	ENSCINP00000011714	annotation not available	Uncharacterized protein.	0.835
ENSCINP00000033882	F6ZJN8_CIOIN	ENSCINP00000033882	ENSCINP00000015598	annotation not available	Uncharacterized protein.	0.477
ENSCINP00000033882	F7ANR5_CIOIN	ENSCINP00000033882	ENSCINP00000015292	annotation not available	CPSF_A domain-containing protein.	0.691
ENSCINP00000033882	H2XJG6_CIOIN	ENSCINP00000033882	ENSCINP00000029798	annotation not available	Uncharacterized protein.	0.540
ENSCINP00000033882	LOC100175879	ENSCINP00000033882	ENSCINP00000002393	annotation not available	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.778
ENSCINP00000033882	LOC100176942	ENSCINP00000033882	ENSCINP00000019290	annotation not available	COP9 signalosome complex subunit 1.	0.974
ENSCINP00000033882	LOC100177051	ENSCINP00000033882	ENSCINP00000017753	annotation not available	PCI domain-containing protein.	0.543
ENSCINP00000033882	LOC100177272	ENSCINP00000033882	ENSCINP00000016166	annotation not available	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.500
ENSCINP00000033882	LOC100177816	ENSCINP00000033882	ENSCINP00000010895	annotation not available	cyclin-H; Belongs to the cyclin family.	0.515
ENSCINP00000033882	LOC100181341	ENSCINP00000033882	ENSCINP00000030207	annotation not available	DNA-directed RNA polymerase II subunit RPB11-a isoform X1.	0.564
ENSCINP00000033882	LOC100182035	ENSCINP00000033882	ENSCINP00000022037	annotation not available	COP9 signalosome complex subunit 8-like.	0.976
ENSCINP00000033882	LOC100182516	ENSCINP00000033882	ENSCINP00000031380	annotation not available	RING-box protein 1.	0.788
ENSCINP00000033882	LOC100183592	ENSCINP00000033882	ENSCINP00000005832	annotation not available	COP9 signalosome complex subunit 4.	0.975
ENSCINP00000033882	LOC100183594	ENSCINP00000033882	ENSCINP00000005835	annotation not available	General transcription and DNA repair factor IIH helicase subunit XPB.	0.545
ENSCINP00000033882	LOC101242260	ENSCINP00000033882	ENSCINP00000032951	annotation not available	DNA-directed RNA polymerases I, II, and III subunit RPABC4.	0.563