37 items (Ciona intestinalis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	H2XVJ2_CIOIN	Uncharacterized protein. (141 aa)
	H2XZ54_CIOIN	RPOLD domain-containing protein. (286 aa)
	LOC100184165	General transcription factor IIH subunit 3-like. (309 aa)
	Zf(c2h2)-114	General transcription factor IIH subunit. (395 aa)
	LOC100183995	Uncharacterized protein. (575 aa)
	F6X618_CIOIN	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (515 aa)
	LOC100183594	General transcription and DNA repair factor IIH helicase subunit XPB. (794 aa)
	LOC100183139	Uncharacterized protein. (1035 aa)
	LOC100186426	Negative elongation factor B. (605 aa)
	LOC100182348	elongin-A3 member D isoform X2. (622 aa)
	F6RMT1_CIOIN	Uncharacterized protein. (551 aa)
	LOC100177778	DNA-directed RNA polymerase II subunit RPB7. (172 aa)
	F6SKY6_CIOIN	HDAg domain-containing protein. (537 aa)
	LOC100177816	cyclin-H; Belongs to the cyclin family. (329 aa)
	LOC100182171	Negative elongation factor E-like. (308 aa)
	LOC100179943	General transcription factor IIF subunit 2. (257 aa)
	F6QR00_CIOIN	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1183 aa)
	F6SAD5_CIOIN	Uncharacterized protein; Belongs to the cyclin family. (514 aa)
	F6S7U3_CIOIN	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (182 aa)
	F6S7T3_CIOIN	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (238 aa)
	LOC100183293	Transcription elongation factor A protein 1. (298 aa)
	LOC100177272	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1814 aa)
	zf(ring)-55	Zinc finger protein. (323 aa)
	LOC100181821	Cyclin-dependent kinase 9; Belongs to the protein kinase superfamily. (376 aa)
	SSRP1	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (603 aa)
	F6PKT6_CIOIN	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (822 aa)
	LOC101242260	DNA-directed RNA polymerases I, II, and III subunit RPABC4. (79 aa)
	LOC100181341	DNA-directed RNA polymerase II subunit RPB11-a isoform X1. (117 aa)
	LOC100178802	Transcription elongation factor SPT5. (1047 aa)
	spt4	Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family. (122 aa)
	H2XJG6_CIOIN	Uncharacterized protein. (211 aa)
	F6TY64_CIOIN	Uncharacterized protein. (388 aa)
	LOC100177815	elongin-C-like; Belongs to the SKP1 family. (114 aa)
	LOC100177537	Protein kinase domain-containing protein. (1105 aa)
	F6XIG6_CIOIN	RPOL4c domain-containing protein. (133 aa)
	LOC100178283	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (152 aa)
	F6Y5Q3_CIOIN	RPOLD domain-containing protein. (151 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6PKT6_CIOIN	F6QR00_CIOIN	ENSCINP00000018238	ENSCINP00000013245	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.921
F6PKT6_CIOIN	F6SAD5_CIOIN	ENSCINP00000018238	ENSCINP00000014389	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.	Uncharacterized protein; Belongs to the cyclin family.	0.803
F6PKT6_CIOIN	F6X618_CIOIN	ENSCINP00000018238	ENSCINP00000003619	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	0.993
F6PKT6_CIOIN	F6XIG6_CIOIN	ENSCINP00000018238	ENSCINP00000021902	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.	RPOL4c domain-containing protein.	0.916
F6PKT6_CIOIN	F6Y5Q3_CIOIN	ENSCINP00000018238	ENSCINP00000019931	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.	RPOLD domain-containing protein.	0.859
F6PKT6_CIOIN	H2XJG6_CIOIN	ENSCINP00000018238	ENSCINP00000029798	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.	Uncharacterized protein.	0.818
F6PKT6_CIOIN	H2XVJ2_CIOIN	ENSCINP00000018238	ENSCINP00000033676	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.	Uncharacterized protein.	0.842
F6PKT6_CIOIN	H2XZ54_CIOIN	ENSCINP00000018238	ENSCINP00000034938	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.	RPOLD domain-containing protein.	0.859
F6PKT6_CIOIN	LOC100177272	ENSCINP00000018238	ENSCINP00000016166	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.978
F6PKT6_CIOIN	LOC100177537	ENSCINP00000018238	ENSCINP00000024069	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.	Protein kinase domain-containing protein.	0.868
F6PKT6_CIOIN	LOC100177778	ENSCINP00000018238	ENSCINP00000010264	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.	DNA-directed RNA polymerase II subunit RPB7.	0.959
F6PKT6_CIOIN	LOC100177816	ENSCINP00000018238	ENSCINP00000010895	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.	cyclin-H; Belongs to the cyclin family.	0.699
F6PKT6_CIOIN	LOC100178283	ENSCINP00000018238	ENSCINP00000021822	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.	0.739
F6PKT6_CIOIN	LOC100178802	ENSCINP00000018238	ENSCINP00000030091	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.	Transcription elongation factor SPT5.	0.883
F6PKT6_CIOIN	LOC100179943	ENSCINP00000018238	ENSCINP00000012710	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.	General transcription factor IIF subunit 2.	0.909
F6PKT6_CIOIN	LOC100181341	ENSCINP00000018238	ENSCINP00000030207	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.	DNA-directed RNA polymerase II subunit RPB11-a isoform X1.	0.841
F6PKT6_CIOIN	LOC100181821	ENSCINP00000018238	ENSCINP00000018002	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.	Cyclin-dependent kinase 9; Belongs to the protein kinase superfamily.	0.771
F6PKT6_CIOIN	LOC100182171	ENSCINP00000018238	ENSCINP00000011919	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.	Negative elongation factor E-like.	0.620
F6PKT6_CIOIN	LOC100182348	ENSCINP00000018238	ENSCINP00000008547	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.	elongin-A3 member D isoform X2.	0.610
F6PKT6_CIOIN	LOC100183139	ENSCINP00000018238	ENSCINP00000006432	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.	Uncharacterized protein.	0.720