57 items (Ciona intestinalis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC100186374	26S proteasome non-ATPase regulatory subunit 11. (420 aa)
	LOC100181511	S-phase kinase-associated protein 1; Belongs to the SKP1 family. (162 aa)
	F6PP61_CIOIN	Proteasome subunit beta; Belongs to the peptidase T1B family. (260 aa)
	F6S376_CIOIN	PA28_alpha domain-containing protein. (82 aa)
	F6XKP0_CIOIN	AAA domain-containing protein; Belongs to the AAA ATPase family. (397 aa)
	F7BHP4_CIOIN	AAA domain-containing protein; Belongs to the AAA ATPase family. (428 aa)
	LOC100182082	AAA domain-containing protein; Belongs to the AAA ATPase family. (463 aa)
	F6UXR3_CIOIN	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (901 aa)
	LOC100184190	AAA domain-containing protein; Belongs to the AAA ATPase family. (419 aa)
	LOC100187071	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (187 aa)
	LOC100184510	PCI domain-containing protein. (386 aa)
	F7A955_CIOIN	Proteasome subunit beta. (221 aa)
	LOC100185384	ubiquitin-60S ribosomal protein L40. (128 aa)
	F6Z1D9_CIOIN	PA28_beta domain-containing protein. (255 aa)
	LOC100183036	Proteasome subunit alpha type. (220 aa)
	F6YHS8_CIOIN	PCI domain-containing protein. (458 aa)
	LOC100177816	cyclin-H; Belongs to the cyclin family. (329 aa)
	F6RUQ3_CIOIN	Proteasome subunit alpha type. (251 aa)
	LOC100185096	26S proteasome regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa)
	F6VVB7_CIOIN	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (315 aa)
	r27a	R27a protein isoform X1. (155 aa)
	F7BLS5_CIOIN	PCI domain-containing protein. (398 aa)
	LOC100183552	ANK_REP_REGION domain-containing protein. (230 aa)
	F6QS20_CIOIN	VWFA domain-containing protein. (370 aa)
	F6PW28_CIOIN	CULLIN_2 domain-containing protein; Belongs to the cullin family. (778 aa)
	LOC100187507	Uncharacterized protein. (510 aa)
	LOC100184104	PCI domain-containing protein. (376 aa)
	F6ZJN8_CIOIN	Uncharacterized protein. (381 aa)
	LOC100177476	Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (251 aa)
	F6S4F7_CIOIN	Non-specific serine/threonine protein kinase. (512 aa)
	LOC100177208	S-phase kinase-associated protein 2. (453 aa)
	LOC100182845	Proteasome subunit alpha type-4-like. (91 aa)
	zf(ring)-55	Zinc finger protein. (323 aa)
	F6T453_CIOIN	Uncharacterized protein; Belongs to the cyclin family. (430 aa)
	LOC100186602	Proteasome subunit beta. (268 aa)
	F6Z491_CIOIN	Proteasome subunit alpha type. (242 aa)
	LOC100187162	AAA domain-containing protein; Belongs to the AAA ATPase family. (393 aa)
	LOC113474124	Proteasome subunit beta. (205 aa)
	F6PI50_CIOIN	Uncharacterized protein. (175 aa)
	LOC100186458	Protein kinase domain-containing protein. (743 aa)
	F6SDU1_CIOIN	PCI domain-containing protein. (270 aa)
	F6V0W8_CIOIN	Uncharacterized protein. (235 aa)
	F7BHX3_CIOIN	Uncharacterized protein. (283 aa)
	F6VJQ1_CIOIN	Uncharacterized protein. (347 aa)
	LOC100183603	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (81 aa)
	H2XJH2_CIOIN	Uncharacterized protein. (216 aa)
	H2XLA2_CIOIN	Uncharacterized protein. (206 aa)
	LOC100179683	26S proteasome non-ATPase regulatory subunit 14. (310 aa)
	LOC113474176	kxDL motif-containing protein 1-like. (139 aa)
	H2XP67_CIOIN	Uncharacterized protein. (64 aa)
	H2XSU1_CIOIN	Proteasome subunit beta. (239 aa)
	H2XT91_CIOIN	Cyclin N-terminal domain-containing protein. (100 aa)
	LOC100179585	Proteasome subunit alpha type. (233 aa)
	zeta	Proteasome subunit beta. (276 aa)
	H2XYW0_CIOIN	MPN domain-containing protein. (323 aa)
	LOC100179460	Proteasome subunit beta. (200 aa)
	H2Y3S9_CIOIN	RPN2_C domain-containing protein. (79 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6PI50_CIOIN	F6PP61_CIOIN	ENSCINP00000020267	ENSCINP00000004728	Uncharacterized protein.	Proteasome subunit beta; Belongs to the peptidase T1B family.	0.929
F6PI50_CIOIN	F6QS20_CIOIN	ENSCINP00000020267	ENSCINP00000013226	Uncharacterized protein.	VWFA domain-containing protein.	0.846
F6PI50_CIOIN	F6RUQ3_CIOIN	ENSCINP00000020267	ENSCINP00000010909	Uncharacterized protein.	Proteasome subunit alpha type.	0.917
F6PI50_CIOIN	F6S376_CIOIN	ENSCINP00000020267	ENSCINP00000006551	Uncharacterized protein.	PA28_alpha domain-containing protein.	0.571
F6PI50_CIOIN	F6SDU1_CIOIN	ENSCINP00000020267	ENSCINP00000024704	Uncharacterized protein.	PCI domain-containing protein.	0.867
F6PI50_CIOIN	F6UXR3_CIOIN	ENSCINP00000020267	ENSCINP00000007427	Uncharacterized protein.	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.	0.774
F6PI50_CIOIN	F6V0W8_CIOIN	ENSCINP00000020267	ENSCINP00000024930	Uncharacterized protein.	Uncharacterized protein.	0.571
F6PI50_CIOIN	F6VJQ1_CIOIN	ENSCINP00000020267	ENSCINP00000026820	Uncharacterized protein.	Uncharacterized protein.	0.481
F6PI50_CIOIN	F6XKP0_CIOIN	ENSCINP00000020267	ENSCINP00000007040	Uncharacterized protein.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.836
F6PI50_CIOIN	F6YHS8_CIOIN	ENSCINP00000020267	ENSCINP00000010751	Uncharacterized protein.	PCI domain-containing protein.	0.831
F6PI50_CIOIN	F6Z1D9_CIOIN	ENSCINP00000020267	ENSCINP00000010715	Uncharacterized protein.	PA28_beta domain-containing protein.	0.571
F6PI50_CIOIN	F6Z491_CIOIN	ENSCINP00000020267	ENSCINP00000018974	Uncharacterized protein.	Proteasome subunit alpha type.	0.914
F6PI50_CIOIN	F6ZJN8_CIOIN	ENSCINP00000020267	ENSCINP00000015598	Uncharacterized protein.	Uncharacterized protein.	0.481
F6PI50_CIOIN	F7A955_CIOIN	ENSCINP00000020267	ENSCINP00000009362	Uncharacterized protein.	Proteasome subunit beta.	0.929
F6PI50_CIOIN	F7BHP4_CIOIN	ENSCINP00000020267	ENSCINP00000007206	Uncharacterized protein.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.830
F6PI50_CIOIN	F7BLS5_CIOIN	ENSCINP00000020267	ENSCINP00000012483	Uncharacterized protein.	PCI domain-containing protein.	0.836
F6PI50_CIOIN	H2XJH2_CIOIN	ENSCINP00000020267	ENSCINP00000029804	Uncharacterized protein.	Uncharacterized protein.	0.729
F6PI50_CIOIN	H2XLA2_CIOIN	ENSCINP00000020267	ENSCINP00000030434	Uncharacterized protein.	Uncharacterized protein.	0.474
F6PI50_CIOIN	H2XSU1_CIOIN	ENSCINP00000020267	ENSCINP00000032725	Uncharacterized protein.	Proteasome subunit beta.	0.931
F6PI50_CIOIN	H2XYW0_CIOIN	ENSCINP00000020267	ENSCINP00000034844	Uncharacterized protein.	MPN domain-containing protein.	0.845