27 items (Ciona intestinalis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC100186373	G1/S-specific cyclin-D2-like; Belongs to the cyclin family. (299 aa)
	E2f4/5	E2F_TDP domain-containing protein. (269 aa)
	H2XPS2_CIOIN	Uncharacterized protein. (232 aa)
	LOC113474176	kxDL motif-containing protein 1-like. (139 aa)
	E2f1/2/3/6	E2F_TDP domain-containing protein. (441 aa)
	LOC100183603	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (81 aa)
	F6VJQ1_CIOIN	Uncharacterized protein. (347 aa)
	F6V6S0_CIOIN	Uncharacterized protein. (714 aa)
	F6SCJ9_CIOIN	Uncharacterized protein. (497 aa)
	F6T283_CIOIN	Uncharacterized protein. (454 aa)
	zf(ring)-55	Zinc finger protein. (323 aa)
	LOC100177208	S-phase kinase-associated protein 2. (453 aa)
	F6ZJN8_CIOIN	Uncharacterized protein. (381 aa)
	F6T957_CIOIN	Uncharacterized protein. (589 aa)
	F6X7U3_CIOIN	LisH domain-containing protein. (1112 aa)
	F6R0X3_CIOIN	EF-hand domain-containing protein. (182 aa)
	F6PW28_CIOIN	CULLIN_2 domain-containing protein; Belongs to the cullin family. (778 aa)
	r27a	R27a protein isoform X1. (155 aa)
	F6VVB7_CIOIN	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (315 aa)
	LOC100177816	cyclin-H; Belongs to the cyclin family. (329 aa)
	LOC100185384	ubiquitin-60S ribosomal protein L40. (128 aa)
	F6WPA9_CIOIN	Uncharacterized protein. (1101 aa)
	LOC100186064	Serine/threonine-protein phosphatase. (314 aa)
	F7AVM0_CIOIN	Uncharacterized protein. (535 aa)
	F7AVR8_CIOIN	Uncharacterized protein. (175 aa)
	dp-1	Uncharacterized protein. (534 aa)
	LOC100181511	S-phase kinase-associated protein 1; Belongs to the SKP1 family. (162 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
E2f1/2/3/6	E2f4/5	ENSCINP00000030840	ENSCINP00000033500	E2F_TDP domain-containing protein.	E2F_TDP domain-containing protein.	0.822
E2f1/2/3/6	F6VVB7_CIOIN	ENSCINP00000030840	ENSCINP00000012022	E2F_TDP domain-containing protein.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.873
E2f1/2/3/6	F6WPA9_CIOIN	ENSCINP00000030840	ENSCINP00000009487	E2F_TDP domain-containing protein.	Uncharacterized protein.	0.960
E2f1/2/3/6	LOC100177208	ENSCINP00000030840	ENSCINP00000016594	E2F_TDP domain-containing protein.	S-phase kinase-associated protein 2.	0.731
E2f1/2/3/6	LOC100181511	ENSCINP00000030840	ENSCINP00000003403	E2F_TDP domain-containing protein.	S-phase kinase-associated protein 1; Belongs to the SKP1 family.	0.514
E2f1/2/3/6	LOC100183603	ENSCINP00000030840	ENSCINP00000029191	E2F_TDP domain-containing protein.	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	0.553
E2f1/2/3/6	LOC100186373	ENSCINP00000030840	ENSCINP00000026930	E2F_TDP domain-containing protein.	G1/S-specific cyclin-D2-like; Belongs to the cyclin family.	0.768
E2f1/2/3/6	dp-1	ENSCINP00000030840	ENSCINP00000003677	E2F_TDP domain-containing protein.	Uncharacterized protein.	0.971
E2f4/5	E2f1/2/3/6	ENSCINP00000033500	ENSCINP00000030840	E2F_TDP domain-containing protein.	E2F_TDP domain-containing protein.	0.822
E2f4/5	F6PW28_CIOIN	ENSCINP00000033500	ENSCINP00000013359	E2F_TDP domain-containing protein.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.634
E2f4/5	F6VVB7_CIOIN	ENSCINP00000033500	ENSCINP00000012022	E2F_TDP domain-containing protein.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.809
E2f4/5	F6WPA9_CIOIN	ENSCINP00000033500	ENSCINP00000009487	E2F_TDP domain-containing protein.	Uncharacterized protein.	0.976
E2f4/5	LOC100177208	ENSCINP00000033500	ENSCINP00000016594	E2F_TDP domain-containing protein.	S-phase kinase-associated protein 2.	0.751
E2f4/5	LOC100181511	ENSCINP00000033500	ENSCINP00000003403	E2F_TDP domain-containing protein.	S-phase kinase-associated protein 1; Belongs to the SKP1 family.	0.614
E2f4/5	LOC100183603	ENSCINP00000033500	ENSCINP00000029191	E2F_TDP domain-containing protein.	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	0.641
E2f4/5	LOC100186373	ENSCINP00000033500	ENSCINP00000026930	E2F_TDP domain-containing protein.	G1/S-specific cyclin-D2-like; Belongs to the cyclin family.	0.780
E2f4/5	dp-1	ENSCINP00000033500	ENSCINP00000003677	E2F_TDP domain-containing protein.	Uncharacterized protein.	0.991
F6PW28_CIOIN	E2f4/5	ENSCINP00000013359	ENSCINP00000033500	CULLIN_2 domain-containing protein; Belongs to the cullin family.	E2F_TDP domain-containing protein.	0.634
F6PW28_CIOIN	F6T957_CIOIN	ENSCINP00000013359	ENSCINP00000015461	CULLIN_2 domain-containing protein; Belongs to the cullin family.	Uncharacterized protein.	0.607
F6PW28_CIOIN	F6VJQ1_CIOIN	ENSCINP00000013359	ENSCINP00000026820	CULLIN_2 domain-containing protein; Belongs to the cullin family.	Uncharacterized protein.	0.718