28 items (Ciona intestinalis) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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co-expression

protein homology

Your Input:
	LOC100184027	mRNA cap guanine-N7 methyltransferase. (398 aa)
	Zf(c2h2)-114	General transcription factor IIH subunit. (395 aa)
	LOC100175699	Polynucleotide 5'-triphosphatase; Bifunctional mRNA-capping enzyme exhibiting RNA 5'- triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus. (602 aa)
	F6X618_CIOIN	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (515 aa)
	LOC100183594	General transcription and DNA repair factor IIH helicase subunit XPB. (794 aa)
	F6RMT1_CIOIN	Uncharacterized protein. (551 aa)
	LOC100177778	DNA-directed RNA polymerase II subunit RPB7. (172 aa)
	LOC100177816	cyclin-H; Belongs to the cyclin family. (329 aa)
	LOC100179943	General transcription factor IIF subunit 2. (257 aa)
	F6QR00_CIOIN	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1183 aa)
	LOC100181274	R3H domain-containing protein. (224 aa)
	F6S7U3_CIOIN	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (182 aa)
	F6S7T3_CIOIN	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (238 aa)
	LOC100177272	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1814 aa)
	zf(ring)-55	Zinc finger protein. (323 aa)
	F6PKJ4_CIOIN	MIF4G domain-containing protein. (795 aa)
	F6Y5Q3_CIOIN	RPOLD domain-containing protein. (151 aa)
	F6YM31_CIOIN	TYR_PHOSPHATASE_2 domain-containing protein. (348 aa)
	LOC100178283	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (152 aa)
	F6XIG6_CIOIN	RPOL4c domain-containing protein. (133 aa)
	H2XJG6_CIOIN	Uncharacterized protein. (211 aa)
	LOC100178802	Transcription elongation factor SPT5. (1047 aa)
	LOC100181341	DNA-directed RNA polymerase II subunit RPB11-a isoform X1. (117 aa)
	LOC101242260	DNA-directed RNA polymerases I, II, and III subunit RPABC4. (79 aa)
	H2XVJ2_CIOIN	Uncharacterized protein. (141 aa)
	LOC100184165	General transcription factor IIH subunit 3-like. (309 aa)
	H2XZ54_CIOIN	RPOLD domain-containing protein. (286 aa)
	H2Y233_CIOIN	Nuclear cap-binding protein subunit 2. (185 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6PKJ4_CIOIN	F6QR00_CIOIN	ENSCINP00000018247	ENSCINP00000013245	MIF4G domain-containing protein.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.724
F6PKJ4_CIOIN	F6RMT1_CIOIN	ENSCINP00000018247	ENSCINP00000009626	MIF4G domain-containing protein.	Uncharacterized protein.	0.651
F6PKJ4_CIOIN	F6X618_CIOIN	ENSCINP00000018247	ENSCINP00000003619	MIF4G domain-containing protein.	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	0.666
F6PKJ4_CIOIN	F6Y5Q3_CIOIN	ENSCINP00000018247	ENSCINP00000019931	MIF4G domain-containing protein.	RPOLD domain-containing protein.	0.592
F6PKJ4_CIOIN	F6YM31_CIOIN	ENSCINP00000018247	ENSCINP00000020998	MIF4G domain-containing protein.	TYR_PHOSPHATASE_2 domain-containing protein.	0.644
F6PKJ4_CIOIN	H2XZ54_CIOIN	ENSCINP00000018247	ENSCINP00000034938	MIF4G domain-containing protein.	RPOLD domain-containing protein.	0.592
F6PKJ4_CIOIN	H2Y233_CIOIN	ENSCINP00000018247	ENSCINP00000035968	MIF4G domain-containing protein.	Nuclear cap-binding protein subunit 2.	0.999
F6PKJ4_CIOIN	LOC100175699	ENSCINP00000018247	ENSCINP00000002175	MIF4G domain-containing protein.	Polynucleotide 5'-triphosphatase; Bifunctional mRNA-capping enzyme exhibiting RNA 5'- triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus.	0.717
F6PKJ4_CIOIN	LOC100177272	ENSCINP00000018247	ENSCINP00000016166	MIF4G domain-containing protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.651
F6PKJ4_CIOIN	LOC100178802	ENSCINP00000018247	ENSCINP00000030091	MIF4G domain-containing protein.	Transcription elongation factor SPT5.	0.702
F6PKJ4_CIOIN	LOC100179943	ENSCINP00000018247	ENSCINP00000012710	MIF4G domain-containing protein.	General transcription factor IIF subunit 2.	0.675
F6PKJ4_CIOIN	LOC100183594	ENSCINP00000018247	ENSCINP00000005835	MIF4G domain-containing protein.	General transcription and DNA repair factor IIH helicase subunit XPB.	0.654
F6PKJ4_CIOIN	LOC100184027	ENSCINP00000018247	ENSCINP00000000584	MIF4G domain-containing protein.	mRNA cap guanine-N7 methyltransferase.	0.871
F6PKJ4_CIOIN	LOC100184165	ENSCINP00000018247	ENSCINP00000033718	MIF4G domain-containing protein.	General transcription factor IIH subunit 3-like.	0.653
F6QR00_CIOIN	F6PKJ4_CIOIN	ENSCINP00000013245	ENSCINP00000018247	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	MIF4G domain-containing protein.	0.724
F6QR00_CIOIN	F6RMT1_CIOIN	ENSCINP00000013245	ENSCINP00000009626	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Uncharacterized protein.	0.931
F6QR00_CIOIN	F6S7T3_CIOIN	ENSCINP00000013245	ENSCINP00000014977	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.868
F6QR00_CIOIN	F6S7U3_CIOIN	ENSCINP00000013245	ENSCINP00000014976	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.868
F6QR00_CIOIN	F6X618_CIOIN	ENSCINP00000013245	ENSCINP00000003619	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	0.995
F6QR00_CIOIN	F6XIG6_CIOIN	ENSCINP00000013245	ENSCINP00000021902	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	RPOL4c domain-containing protein.	0.999