43 items (Ciona intestinalis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

Your Input:
	Zf(c2h2)-114	General transcription factor IIH subunit. (395 aa)
	H2Y332_CIOIN	DUF3591 domain-containing protein. (202 aa)
	H2Y0S6_CIOIN	Uncharacterized protein. (1003 aa)
	H2XZ54_CIOIN	RPOLD domain-containing protein. (286 aa)
	H2XW76_CIOIN	TAF domain-containing protein. (526 aa)
	LOC100184165	General transcription factor IIH subunit 3-like. (309 aa)
	H2XVJ2_CIOIN	Uncharacterized protein. (141 aa)
	LOC101242260	DNA-directed RNA polymerases I, II, and III subunit RPABC4. (79 aa)
	H2XQB7_CIOIN	PHD-type domain-containing protein. (164 aa)
	LOC100181341	DNA-directed RNA polymerase II subunit RPB11-a isoform X1. (117 aa)
	H2XJG6_CIOIN	Uncharacterized protein. (211 aa)
	F7BHW5_CIOIN	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (284 aa)
	LOC100177176	Uncharacterized protein. (181 aa)
	F7ATY3_CIOIN	Uncharacterized protein. (121 aa)
	F6Z277_CIOIN	Uncharacterized protein. (210 aa)
	F6XIG6_CIOIN	RPOL4c domain-containing protein. (133 aa)
	LOC100178283	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (152 aa)
	F6Y5Q3_CIOIN	RPOLD domain-containing protein. (151 aa)
	LOC100182343	Transcription initiation factor IIB-like. (314 aa)
	F6U8F8_CIOIN	TAFH domain-containing protein. (598 aa)
	LOC100178079	Sperm-associated antigen 16 protein. (606 aa)
	zf(ring)-55	Zinc finger protein. (323 aa)
	LOC100177272	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1814 aa)
	F6S7T3_CIOIN	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (238 aa)
	F6S7U3_CIOIN	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (182 aa)
	F6QR00_CIOIN	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1183 aa)
	LOC100179943	General transcription factor IIF subunit 2. (257 aa)
	F7AWC6_CIOIN	WD_REPEATS_REGION domain-containing protein. (272 aa)
	F7AWN2_CIOIN	LisH domain-containing protein. (321 aa)
	LOC100177816	cyclin-H; Belongs to the cyclin family. (329 aa)
	LOC100177778	DNA-directed RNA polymerase II subunit RPB7. (172 aa)
	F6RMT1_CIOIN	Uncharacterized protein. (551 aa)
	F6YGZ1_CIOIN	Uncharacterized protein. (587 aa)
	F6Y8T6_CIOIN	TAFII55_N domain-containing protein. (166 aa)
	LOC100183594	General transcription and DNA repair factor IIH helicase subunit XPB. (794 aa)
	F6UE50_CIOIN	BTP domain-containing protein. (671 aa)
	LOC100177214	Uncharacterized protein. (316 aa)
	LOC100181502	TFIID_20kDa domain-containing protein. (187 aa)
	F7A363_CIOIN	TBP-binding domain-containing protein. (480 aa)
	F6SJW4_CIOIN	Uncharacterized protein. (613 aa)
	LOC100179515	TFIIA-alpha and beta-like factor isoform X1. (332 aa)
	F6X618_CIOIN	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (515 aa)
	LOC100175005	HTH TFE/IIEalpha-type domain-containing protein. (343 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6QR00_CIOIN	F6RMT1_CIOIN	ENSCINP00000013245	ENSCINP00000009626	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Uncharacterized protein.	0.931
F6QR00_CIOIN	F6S7T3_CIOIN	ENSCINP00000013245	ENSCINP00000014977	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.868
F6QR00_CIOIN	F6S7U3_CIOIN	ENSCINP00000013245	ENSCINP00000014976	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.868
F6QR00_CIOIN	F6SJW4_CIOIN	ENSCINP00000013245	ENSCINP00000003774	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Uncharacterized protein.	0.665
F6QR00_CIOIN	F6U8F8_CIOIN	ENSCINP00000013245	ENSCINP00000019437	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	TAFH domain-containing protein.	0.764
F6QR00_CIOIN	F6UE50_CIOIN	ENSCINP00000013245	ENSCINP00000005505	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	BTP domain-containing protein.	0.683
F6QR00_CIOIN	F6X618_CIOIN	ENSCINP00000013245	ENSCINP00000003619	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	0.995
F6QR00_CIOIN	F6XIG6_CIOIN	ENSCINP00000013245	ENSCINP00000021902	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	RPOL4c domain-containing protein.	0.999
F6QR00_CIOIN	F6Y5Q3_CIOIN	ENSCINP00000013245	ENSCINP00000019931	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	RPOLD domain-containing protein.	0.983
F6QR00_CIOIN	F6Y8T6_CIOIN	ENSCINP00000013245	ENSCINP00000007361	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	TAFII55_N domain-containing protein.	0.783
F6QR00_CIOIN	F6YGZ1_CIOIN	ENSCINP00000013245	ENSCINP00000008460	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Uncharacterized protein.	0.647
F6QR00_CIOIN	F6Z277_CIOIN	ENSCINP00000013245	ENSCINP00000022479	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Uncharacterized protein.	0.916
F6QR00_CIOIN	F7A363_CIOIN	ENSCINP00000013245	ENSCINP00000003814	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	TBP-binding domain-containing protein.	0.637
F6QR00_CIOIN	F7ATY3_CIOIN	ENSCINP00000013245	ENSCINP00000023377	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Uncharacterized protein.	0.797
F6QR00_CIOIN	F7AWC6_CIOIN	ENSCINP00000013245	ENSCINP00000011057	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	WD_REPEATS_REGION domain-containing protein.	0.647
F6QR00_CIOIN	F7AWN2_CIOIN	ENSCINP00000013245	ENSCINP00000011046	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	LisH domain-containing protein.	0.638
F6QR00_CIOIN	F7BHW5_CIOIN	ENSCINP00000013245	ENSCINP00000026391	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.	0.958
F6QR00_CIOIN	H2XJG6_CIOIN	ENSCINP00000013245	ENSCINP00000029798	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Uncharacterized protein.	0.999
F6QR00_CIOIN	H2XQB7_CIOIN	ENSCINP00000013245	ENSCINP00000031851	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	PHD-type domain-containing protein.	0.683
F6QR00_CIOIN	H2XVJ2_CIOIN	ENSCINP00000013245	ENSCINP00000033676	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Uncharacterized protein.	0.999