54 items (Ciona intestinalis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Zf(c2h2)-114	General transcription factor IIH subunit. (395 aa)
	F6RMT1_CIOIN	Uncharacterized protein. (551 aa)
	LOC100177778	DNA-directed RNA polymerase II subunit RPB7. (172 aa)
	F6SKY6_CIOIN	HDAg domain-containing protein. (537 aa)
	LOC100177816	cyclin-H; Belongs to the cyclin family. (329 aa)
	LOC100182171	Negative elongation factor E-like. (308 aa)
	LOC100178614	AF4/FMR2 family member 4 isoform X3. (1084 aa)
	F6VS86_CIOIN	AHD domain-containing protein. (660 aa)
	LOC100179943	General transcription factor IIF subunit 2. (257 aa)
	F6PX81_CIOIN	Plus3 domain-containing protein. (336 aa)
	F6QR00_CIOIN	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1183 aa)
	F6SAD5_CIOIN	Uncharacterized protein; Belongs to the cyclin family. (514 aa)
	F6S7U3_CIOIN	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (182 aa)
	F6S7T3_CIOIN	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (238 aa)
	F6SJH8_CIOIN	S1 motif domain-containing protein. (450 aa)
	F6SJ61_CIOIN	HTH_44 domain-containing protein. (505 aa)
	LOC100183293	Transcription elongation factor A protein 1. (298 aa)
	LOC100177272	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1814 aa)
	zf(ring)-55	Zinc finger protein. (323 aa)
	LOC494392	Uncharacterized protein LOC494392. (131 aa)
	LOC100181821	Cyclin-dependent kinase 9; Belongs to the protein kinase superfamily. (376 aa)
	F6PKT6_CIOIN	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (822 aa)
	F6PKJ4_CIOIN	MIF4G domain-containing protein. (795 aa)
	LOC100175816	TPR_REGION domain-containing protein. (1034 aa)
	F6Y5Q3_CIOIN	RPOLD domain-containing protein. (151 aa)
	LOC100178283	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (152 aa)
	F6XIG6_CIOIN	RPOL4c domain-containing protein. (133 aa)
	F6X941_CIOIN	Uncharacterized protein. (296 aa)
	LOC100177815	elongin-C-like; Belongs to the SKP1 family. (114 aa)
	F6XB76_CIOIN	SPT6_acidic domain-containing protein. (206 aa)
	F6YZE6_CIOIN	Uncharacterized protein. (166 aa)
	H2XJG6_CIOIN	Uncharacterized protein. (211 aa)
	spt4	Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family. (122 aa)
	LOC100178802	Transcription elongation factor SPT5. (1047 aa)
	LOC100181341	DNA-directed RNA polymerase II subunit RPB11-a isoform X1. (117 aa)
	H2XNY4_CIOIN	EAF domain-containing protein. (241 aa)
	LOC100182087	WD repeat-containing protein 61-like. (305 aa)
	H2XQ36_CIOIN	Uncharacterized protein. (312 aa)
	LOC101242260	DNA-directed RNA polymerases I, II, and III subunit RPABC4. (79 aa)
	H2XTY0_CIOIN	Uncharacterized protein. (204 aa)
	H2XU12_CIOIN	Uncharacterized protein. (189 aa)
	H2XUU5_CIOIN	Uncharacterized protein. (532 aa)
	H2XVJ2_CIOIN	Uncharacterized protein. (141 aa)
	LOC100184165	General transcription factor IIH subunit 3-like. (309 aa)
	H2XZ54_CIOIN	RPOLD domain-containing protein. (286 aa)
	H2Y233_CIOIN	Nuclear cap-binding protein subunit 2. (185 aa)
	SSRP1	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (603 aa)
	LOC100183995	Uncharacterized protein. (575 aa)
	F6X618_CIOIN	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (515 aa)
	LOC100183594	General transcription and DNA repair factor IIH helicase subunit XPB. (794 aa)
	LOC100183139	Uncharacterized protein. (1035 aa)
	LOC100187539	TFIIS N-terminal domain-containing protein. (658 aa)
	LOC100186426	Negative elongation factor B. (605 aa)
	LOC100182348	elongin-A3 member D isoform X2. (622 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6PKJ4_CIOIN	F6PKT6_CIOIN	ENSCINP00000018247	ENSCINP00000018238	MIF4G domain-containing protein.	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.	0.661
F6PKJ4_CIOIN	F6QR00_CIOIN	ENSCINP00000018247	ENSCINP00000013245	MIF4G domain-containing protein.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.724
F6PKJ4_CIOIN	F6RMT1_CIOIN	ENSCINP00000018247	ENSCINP00000009626	MIF4G domain-containing protein.	Uncharacterized protein.	0.651
F6PKJ4_CIOIN	F6SAD5_CIOIN	ENSCINP00000018247	ENSCINP00000014389	MIF4G domain-containing protein.	Uncharacterized protein; Belongs to the cyclin family.	0.635
F6PKJ4_CIOIN	F6SKY6_CIOIN	ENSCINP00000018247	ENSCINP00000010608	MIF4G domain-containing protein.	HDAg domain-containing protein.	0.633
F6PKJ4_CIOIN	F6VS86_CIOIN	ENSCINP00000018247	ENSCINP00000012639	MIF4G domain-containing protein.	AHD domain-containing protein.	0.420
F6PKJ4_CIOIN	F6X618_CIOIN	ENSCINP00000018247	ENSCINP00000003619	MIF4G domain-containing protein.	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	0.666
F6PKJ4_CIOIN	F6Y5Q3_CIOIN	ENSCINP00000018247	ENSCINP00000019931	MIF4G domain-containing protein.	RPOLD domain-containing protein.	0.592
F6PKJ4_CIOIN	F6YZE6_CIOIN	ENSCINP00000018247	ENSCINP00000027885	MIF4G domain-containing protein.	Uncharacterized protein.	0.501
F6PKJ4_CIOIN	H2XUU5_CIOIN	ENSCINP00000018247	ENSCINP00000033429	MIF4G domain-containing protein.	Uncharacterized protein.	0.439
F6PKJ4_CIOIN	H2XZ54_CIOIN	ENSCINP00000018247	ENSCINP00000034938	MIF4G domain-containing protein.	RPOLD domain-containing protein.	0.592
F6PKJ4_CIOIN	H2Y233_CIOIN	ENSCINP00000018247	ENSCINP00000035968	MIF4G domain-containing protein.	Nuclear cap-binding protein subunit 2.	0.999
F6PKJ4_CIOIN	LOC100177272	ENSCINP00000018247	ENSCINP00000016166	MIF4G domain-containing protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.651
F6PKJ4_CIOIN	LOC100178614	ENSCINP00000018247	ENSCINP00000012312	MIF4G domain-containing protein.	AF4/FMR2 family member 4 isoform X3.	0.478
F6PKJ4_CIOIN	LOC100178802	ENSCINP00000018247	ENSCINP00000030091	MIF4G domain-containing protein.	Transcription elongation factor SPT5.	0.702
F6PKJ4_CIOIN	LOC100179943	ENSCINP00000018247	ENSCINP00000012710	MIF4G domain-containing protein.	General transcription factor IIF subunit 2.	0.675
F6PKJ4_CIOIN	LOC100181821	ENSCINP00000018247	ENSCINP00000018002	MIF4G domain-containing protein.	Cyclin-dependent kinase 9; Belongs to the protein kinase superfamily.	0.494
F6PKJ4_CIOIN	LOC100182171	ENSCINP00000018247	ENSCINP00000011919	MIF4G domain-containing protein.	Negative elongation factor E-like.	0.951
F6PKJ4_CIOIN	LOC100183139	ENSCINP00000018247	ENSCINP00000006432	MIF4G domain-containing protein.	Uncharacterized protein.	0.419
F6PKJ4_CIOIN	LOC100183293	ENSCINP00000018247	ENSCINP00000015914	MIF4G domain-containing protein.	Transcription elongation factor A protein 1.	0.462