26 items (Ciona intestinalis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC100184027	mRNA cap guanine-N7 methyltransferase. (398 aa)
	Zf(c2h2)-114	General transcription factor IIH subunit. (395 aa)
	LOC100175699	Polynucleotide 5'-triphosphatase; Bifunctional mRNA-capping enzyme exhibiting RNA 5'- triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus. (602 aa)
	F6X618_CIOIN	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (515 aa)
	LOC100183594	General transcription and DNA repair factor IIH helicase subunit XPB. (794 aa)
	F6RMT1_CIOIN	Uncharacterized protein. (551 aa)
	LOC100177778	DNA-directed RNA polymerase II subunit RPB7. (172 aa)
	LOC100177816	cyclin-H; Belongs to the cyclin family. (329 aa)
	LOC100179943	General transcription factor IIF subunit 2. (257 aa)
	F6QR00_CIOIN	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1183 aa)
	LOC100181274	R3H domain-containing protein. (224 aa)
	F6S7U3_CIOIN	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (182 aa)
	F6S7T3_CIOIN	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (238 aa)
	LOC100177272	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1814 aa)
	zf(ring)-55	Zinc finger protein. (323 aa)
	F6Y5Q3_CIOIN	RPOLD domain-containing protein. (151 aa)
	F6YM31_CIOIN	TYR_PHOSPHATASE_2 domain-containing protein. (348 aa)
	LOC100178283	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (152 aa)
	F6XIG6_CIOIN	RPOL4c domain-containing protein. (133 aa)
	H2XJG6_CIOIN	Uncharacterized protein. (211 aa)
	LOC100178802	Transcription elongation factor SPT5. (1047 aa)
	LOC100181341	DNA-directed RNA polymerase II subunit RPB11-a isoform X1. (117 aa)
	LOC101242260	DNA-directed RNA polymerases I, II, and III subunit RPABC4. (79 aa)
	H2XVJ2_CIOIN	Uncharacterized protein. (141 aa)
	LOC100184165	General transcription factor IIH subunit 3-like. (309 aa)
	H2XZ54_CIOIN	RPOLD domain-containing protein. (286 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6QR00_CIOIN	F6RMT1_CIOIN	ENSCINP00000013245	ENSCINP00000009626	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Uncharacterized protein.	0.931
F6QR00_CIOIN	F6S7T3_CIOIN	ENSCINP00000013245	ENSCINP00000014977	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.868
F6QR00_CIOIN	F6S7U3_CIOIN	ENSCINP00000013245	ENSCINP00000014976	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.868
F6QR00_CIOIN	F6X618_CIOIN	ENSCINP00000013245	ENSCINP00000003619	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	0.995
F6QR00_CIOIN	F6XIG6_CIOIN	ENSCINP00000013245	ENSCINP00000021902	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	RPOL4c domain-containing protein.	0.999
F6QR00_CIOIN	F6Y5Q3_CIOIN	ENSCINP00000013245	ENSCINP00000019931	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	RPOLD domain-containing protein.	0.983
F6QR00_CIOIN	F6YM31_CIOIN	ENSCINP00000013245	ENSCINP00000020998	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	TYR_PHOSPHATASE_2 domain-containing protein.	0.581
F6QR00_CIOIN	H2XJG6_CIOIN	ENSCINP00000013245	ENSCINP00000029798	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Uncharacterized protein.	0.999
F6QR00_CIOIN	H2XVJ2_CIOIN	ENSCINP00000013245	ENSCINP00000033676	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Uncharacterized protein.	0.999
F6QR00_CIOIN	H2XZ54_CIOIN	ENSCINP00000013245	ENSCINP00000034938	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	RPOLD domain-containing protein.	0.983
F6QR00_CIOIN	LOC100175699	ENSCINP00000013245	ENSCINP00000002175	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Polynucleotide 5'-triphosphatase; Bifunctional mRNA-capping enzyme exhibiting RNA 5'- triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus.	0.667
F6QR00_CIOIN	LOC100177272	ENSCINP00000013245	ENSCINP00000016166	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.999
F6QR00_CIOIN	LOC100177778	ENSCINP00000013245	ENSCINP00000010264	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	DNA-directed RNA polymerase II subunit RPB7.	0.999
F6QR00_CIOIN	LOC100177816	ENSCINP00000013245	ENSCINP00000010895	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	cyclin-H; Belongs to the cyclin family.	0.900
F6QR00_CIOIN	LOC100178283	ENSCINP00000013245	ENSCINP00000021822	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.	0.999
F6QR00_CIOIN	LOC100178802	ENSCINP00000013245	ENSCINP00000030091	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Transcription elongation factor SPT5.	0.997
F6QR00_CIOIN	LOC100179943	ENSCINP00000013245	ENSCINP00000012710	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	General transcription factor IIF subunit 2.	0.995
F6QR00_CIOIN	LOC100181341	ENSCINP00000013245	ENSCINP00000030207	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	DNA-directed RNA polymerase II subunit RPB11-a isoform X1.	0.999
F6QR00_CIOIN	LOC100183594	ENSCINP00000013245	ENSCINP00000005835	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	General transcription and DNA repair factor IIH helicase subunit XPB.	0.950
F6QR00_CIOIN	LOC100184027	ENSCINP00000013245	ENSCINP00000000584	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	mRNA cap guanine-N7 methyltransferase.	0.738