(25 nodes) Nucleotide salvage network (Ciona intestinalis)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Your Input:
	H2XZV1_CIOIN	Uncharacterized protein. (241 aa)
	F6ZVE1_CIOIN	Uncharacterized protein. (604 aa)
	F6WSV9_CIOIN	A_deaminase domain-containing protein. (361 aa)
	F6WZU2_CIOIN	dNK domain-containing protein. (265 aa)
	LOC100181600	Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (223 aa)
	F6S256_CIOIN	Plastocyanin-like domain-containing protein. (206 aa)
	LOC100186604	Uridine-cytidine kinase; Belongs to the uridine kinase family. (505 aa)
	LOC100175447	PfkB domain-containing protein. (356 aa)
	F6YQS6_CIOIN	AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (651 aa)
	LOC100182436	GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (346 aa)
	F6VKX1_CIOIN	Uridine-cytidine kinase; Belongs to the uridine kinase family. (243 aa)
	F6Z6J2_CIOIN	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (296 aa)
	LOC100178005	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (136 aa)
	F7B963_CIOIN	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (136 aa)
	LOC100178773	NHL repeat-containing protein 2. (454 aa)
	H2XN07_CIOIN	Plastocyanin-like domain-containing protein. (195 aa)
	LOC100184518	Uridine phosphorylase 2. (311 aa)
	H2XPZ0_CIOIN	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (155 aa)
	H2XT70_CIOIN	Thymidine kinase. (177 aa)
	H2XWR4_CIOIN	A_deaminase domain-containing protein. (208 aa)
	H2XZK6_CIOIN	A_deaminase domain-containing protein. (365 aa)
	LOC100186031	Adenine phosphoribosyltransferase-like. (185 aa)
	H2Y1X1_CIOIN	Uncharacterized protein. (324 aa)
	H2Y207_CIOIN	A_deaminase domain-containing protein. (263 aa)
	H2Y239_CIOIN	Plastocyanin-like domain-containing protein. (201 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6VKX1_CIOIN	F7B963_CIOIN	ENSCINP00000014825	ENSCINP00000022100	Uridine-cytidine kinase; Belongs to the uridine kinase family.	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.	0.947
F6VKX1_CIOIN	H2XPZ0_CIOIN	ENSCINP00000014825	ENSCINP00000031724	Uridine-cytidine kinase; Belongs to the uridine kinase family.	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.	0.947
F6VKX1_CIOIN	H2XT70_CIOIN	ENSCINP00000014825	ENSCINP00000032854	Uridine-cytidine kinase; Belongs to the uridine kinase family.	Thymidine kinase.	0.460
F6VKX1_CIOIN	LOC100178005	ENSCINP00000014825	ENSCINP00000020265	Uridine-cytidine kinase; Belongs to the uridine kinase family.	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.	0.947
F6VKX1_CIOIN	LOC100184518	ENSCINP00000014825	ENSCINP00000031490	Uridine-cytidine kinase; Belongs to the uridine kinase family.	Uridine phosphorylase 2.	0.939
F6VKX1_CIOIN	LOC100186604	ENSCINP00000014825	ENSCINP00000007462	Uridine-cytidine kinase; Belongs to the uridine kinase family.	Uridine-cytidine kinase; Belongs to the uridine kinase family.	0.936
F6WSV9_CIOIN	F6WZU2_CIOIN	ENSCINP00000004062	ENSCINP00000005755	A_deaminase domain-containing protein.	dNK domain-containing protein.	0.914
F6WSV9_CIOIN	F6Z6J2_CIOIN	ENSCINP00000004062	ENSCINP00000016539	A_deaminase domain-containing protein.	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.	0.977
F6WSV9_CIOIN	LOC100175447	ENSCINP00000004062	ENSCINP00000009198	A_deaminase domain-containing protein.	PfkB domain-containing protein.	0.978
F6WSV9_CIOIN	LOC100181600	ENSCINP00000004062	ENSCINP00000006226	A_deaminase domain-containing protein.	Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.	0.698
F6WSV9_CIOIN	LOC100184518	ENSCINP00000004062	ENSCINP00000031490	A_deaminase domain-containing protein.	Uridine phosphorylase 2.	0.494
F6WSV9_CIOIN	LOC100186031	ENSCINP00000004062	ENSCINP00000035369	A_deaminase domain-containing protein.	Adenine phosphoribosyltransferase-like.	0.866
F6WZU2_CIOIN	F6WSV9_CIOIN	ENSCINP00000005755	ENSCINP00000004062	dNK domain-containing protein.	A_deaminase domain-containing protein.	0.914
F6WZU2_CIOIN	F6YQS6_CIOIN	ENSCINP00000005755	ENSCINP00000011173	dNK domain-containing protein.	AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.	0.907
F6WZU2_CIOIN	F6Z6J2_CIOIN	ENSCINP00000005755	ENSCINP00000016539	dNK domain-containing protein.	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.	0.912
F6WZU2_CIOIN	F7B963_CIOIN	ENSCINP00000005755	ENSCINP00000022100	dNK domain-containing protein.	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.	0.954
F6WZU2_CIOIN	H2XPZ0_CIOIN	ENSCINP00000005755	ENSCINP00000031724	dNK domain-containing protein.	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.	0.954
F6WZU2_CIOIN	H2XT70_CIOIN	ENSCINP00000005755	ENSCINP00000032854	dNK domain-containing protein.	Thymidine kinase.	0.712
F6WZU2_CIOIN	H2Y207_CIOIN	ENSCINP00000005755	ENSCINP00000035942	dNK domain-containing protein.	A_deaminase domain-containing protein.	0.907
F6WZU2_CIOIN	LOC100175447	ENSCINP00000005755	ENSCINP00000009198	dNK domain-containing protein.	PfkB domain-containing protein.	0.933