106 items (Ciona intestinalis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC100184966	Histone H2B-like; Belongs to the histone H2B family. (121 aa)
	LOC100185899	Epidermal retinol dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (304 aa)
	LOC100177697	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (236 aa)
	F6YRG2_CIOIN	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (211 aa)
	F6S880_CIOIN	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (298 aa)
	LOC100185129	Retinol dehydrogenase 14-like; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (310 aa)
	F6YIX5_CIOIN	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (476 aa)
	F6X618_CIOIN	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (515 aa)
	LOC100179515	TFIIA-alpha and beta-like factor isoform X1. (332 aa)
	rxr	Nuclear receptor. (507 aa)
	LOC100185085	Protein-serine/threonine kinase. (428 aa)
	elk	Transcription factor protein. (946 aa)
	F6RAB3_CIOIN	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (430 aa)
	LOC100177214	Uncharacterized protein. (316 aa)
	LOC100185651	G protein pathway suppressor 2 isoform X1. (323 aa)
	F7BBJ9_CIOIN	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (357 aa)
	F6XKL3_CIOIN	Uncharacterized protein. (255 aa)
	F6XKJ1_CIOIN	Uncharacterized protein. (255 aa)
	F6WXR3_CIOIN	Uncharacterized protein. (764 aa)
	F6U6E1_CIOIN	CXXC-type domain-containing protein. (146 aa)
	F7AW82_CIOIN	Carn_acyltransf domain-containing protein; Belongs to the carnitine/choline acetyltransferase family. (662 aa)
	LOC100182745	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. (347 aa)
	F6YG59_CIOIN	Uncharacterized protein. (91 aa)
	F6PLW6_CIOIN	Uncharacterized protein. (324 aa)
	F6R8N5_CIOIN	Uncharacterized protein; Belongs to the cytochrome P450 family. (593 aa)
	LOC100177778	DNA-directed RNA polymerase II subunit RPB7. (172 aa)
	F6TXI5_CIOIN	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (227 aa)
	LOC100181359	Retinol dehydrogenase 14-like; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (305 aa)
	gi1	G protein alpha subunit Gi splicing variant CiGi1a. (354 aa)
	LOC100180314	Retinol dehydrogenase 13-like; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (272 aa)
	LOC100183843	Histone H2A; Belongs to the histone H2A family. (128 aa)
	F6YFB9_CIOIN	S1 motif domain-containing protein. (771 aa)
	LOC100184477	Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (385 aa)
	LOC100179943	General transcription factor IIF subunit 2. (257 aa)
	F6PR32_CIOIN	Uncharacterized protein. (354 aa)
	LOC100184120	CS domain-containing protein. (193 aa)
	F6QR00_CIOIN	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1183 aa)
	LOC100187100	Lysine-specific histone demethylase 1A. (705 aa)
	rar	Uncharacterized protein. (638 aa)
	F6WVT9_CIOIN	Protein kinase domain-containing protein. (505 aa)
	F6Y836_CIOIN	Uncharacterized protein. (557 aa)
	L7N0T2_CIOIN	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (80 aa)
	LOC100176963	Retinal dehydrogenase 1-like; Belongs to the aldehyde dehydrogenase family. (496 aa)
	F6W5P6_CIOIN	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (498 aa)
	LOC100177272	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1814 aa)
	LOC100180469	Retinal dehydrogenase 2. (538 aa)
	F6WR85_CIOIN	Dihydrolipoyl dehydrogenase. (509 aa)
	F6S4F7_CIOIN	Non-specific serine/threonine protein kinase. (512 aa)
	usf	Transcription factor protein. (325 aa)
	F6PIY6_CIOIN	GPS2_interact domain-containing protein. (373 aa)
	F6QZH0_CIOIN	Protein kinase domain-containing protein. (459 aa)
	LOC100181821	Cyclin-dependent kinase 9; Belongs to the protein kinase superfamily. (376 aa)
	F6QXC2_CIOIN	Uncharacterized protein. (538 aa)
	F6R7T5_CIOIN	Uncharacterized protein. (1533 aa)
	cbfb	Core-binding factor, b subunit isoform X1. (181 aa)
	F6Y5Q3_CIOIN	RPOLD domain-containing protein. (151 aa)
	F6S294_CIOIN	Uncharacterized protein. (256 aa)
	LOC100178283	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (152 aa)
	F7ADJ3_CIOIN	Uncharacterized protein. (337 aa)
	F6XIG6_CIOIN	RPOL4c domain-containing protein. (133 aa)
	F6Z277_CIOIN	Uncharacterized protein. (210 aa)
	LOC100181604	Uncharacterized protein LOC100181604. (254 aa)
	F6UIG7_CIOIN	CARM1 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (461 aa)
	LOC100176140	KN motif and ankyrin repeat domain-containing protein 1-like isoform X1. (1238 aa)
	LOC100179397	Uncharacterized protein LOC100179397; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (256 aa)
	F6YNJ1_CIOIN	HATPase_c domain-containing protein. (666 aa)
	LOC100179350	Retinol dehydrogenase 12-like isoform X1. (313 aa)
	ppar	Nuclear receptor. (644 aa)
	F7BLX7_CIOIN	SH2 domain-containing protein. (245 aa)
	F7BLX1_CIOIN	Uncharacterized protein. (253 aa)
	F6YX18_CIOIN	Uncharacterized protein; Belongs to the cytochrome P450 family. (524 aa)
	F6TCN9_CIOIN	C3H1-type domain-containing protein. (205 aa)
	F6YAH3_CIOIN	Uncharacterized protein. (840 aa)
	F7BH52_CIOIN	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (508 aa)
	F6YR71_CIOIN	Peptidylprolyl isomerase. (439 aa)
	F6Y6M4_CIOIN	Uncharacterized protein. (343 aa)
	F6VKL9_CIOIN	Uncharacterized protein. (314 aa)
	F6XYH1_CIOIN	Uncharacterized protein. (418 aa)
	F6X4N7_CIOIN	Serine/threonine-protein phosphatase. (324 aa)
	F7A0C5_CIOIN	Coilin_N domain-containing protein. (512 aa)
	H2XJG6_CIOIN	Uncharacterized protein. (211 aa)
	H2XJL6_CIOIN	Uncharacterized protein. (259 aa)
	H2XJR2_CIOIN	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (314 aa)
	H2XJR7_CIOIN	Uncharacterized protein. (172 aa)
	LOC100184417	Exportin-1. (1071 aa)
	LOC100181341	DNA-directed RNA polymerase II subunit RPB11-a isoform X1. (117 aa)
	H2XME1_CIOIN	TPR_REGION domain-containing protein. (223 aa)
	LOC100178517	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (142 aa)
	H2XP47_CIOIN	G protein gamma domain-containing protein. (68 aa)
	H2XS77_CIOIN	Uncharacterized protein. (259 aa)
	zf(c2h2)-66	Zinc finger protein (C2H2)-66. (337 aa)
	LOC100183764	Aldehyde dehydrogenase, mitochondrial; Belongs to the aldehyde dehydrogenase family. (495 aa)
	LOC101242260	DNA-directed RNA polymerases I, II, and III subunit RPABC4. (79 aa)
	H2XVJ2_CIOIN	Uncharacterized protein. (141 aa)
	foxa-a	Transcription factor protein isoform 1. (633 aa)
	H2XXW5_CIOIN	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
	LOC100187443	Retinol dehydrogenase 12-like; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (331 aa)
	H2XZ54_CIOIN	RPOLD domain-containing protein. (286 aa)
	H2XZH2_CIOIN	Uncharacterized protein. (321 aa)
	LOC100187056	Uncharacterized protein. (255 aa)
	LOC100185742	Guanine nucleotide-binding protein subunit beta-5. (376 aa)
	H2Y0B7_CIOIN	Uncharacterized protein. (498 aa)
	H2Y0G9_CIOIN	WD_REPEATS_REGION domain-containing protein. (692 aa)
	H2Y1Q1_CIOIN	Uncharacterized protein. (356 aa)
	H2Y3C0_CIOIN	Fork-head domain-containing protein. (235 aa)
	H2Y3Q1_CIOIN	Carn_acyltransf domain-containing protein. (719 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6PIY6_CIOIN	F6QXC2_CIOIN	ENSCINP00000016774	ENSCINP00000018080	GPS2_interact domain-containing protein.	Uncharacterized protein.	0.971
F6PIY6_CIOIN	F6R7T5_CIOIN	ENSCINP00000016774	ENSCINP00000018331	GPS2_interact domain-containing protein.	Uncharacterized protein.	0.721
F6PIY6_CIOIN	F6RAB3_CIOIN	ENSCINP00000016774	ENSCINP00000004801	GPS2_interact domain-containing protein.	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	0.962
F6PIY6_CIOIN	F6UIG7_CIOIN	ENSCINP00000016774	ENSCINP00000022837	GPS2_interact domain-containing protein.	CARM1 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	0.562
F6PIY6_CIOIN	F6Y836_CIOIN	ENSCINP00000016774	ENSCINP00000014778	GPS2_interact domain-containing protein.	Uncharacterized protein.	0.839
F6PIY6_CIOIN	F6Z277_CIOIN	ENSCINP00000016774	ENSCINP00000022479	GPS2_interact domain-containing protein.	Uncharacterized protein.	0.562
F6PIY6_CIOIN	F7A0C5_CIOIN	ENSCINP00000016774	ENSCINP00000029374	GPS2_interact domain-containing protein.	Coilin_N domain-containing protein.	0.920
F6PIY6_CIOIN	LOC100177214	ENSCINP00000016774	ENSCINP00000005464	GPS2_interact domain-containing protein.	Uncharacterized protein.	0.804
F6PIY6_CIOIN	ppar	ENSCINP00000016774	ENSCINP00000024308	GPS2_interact domain-containing protein.	Nuclear receptor.	0.728
F6PIY6_CIOIN	rar	ENSCINP00000016774	ENSCINP00000014259	GPS2_interact domain-containing protein.	Uncharacterized protein.	0.817
F6PIY6_CIOIN	rxr	ENSCINP00000016774	ENSCINP00000003701	GPS2_interact domain-containing protein.	Nuclear receptor.	0.946
F6PIY6_CIOIN	zf(c2h2)-66	ENSCINP00000016774	ENSCINP00000032514	GPS2_interact domain-containing protein.	Zinc finger protein (C2H2)-66.	0.493
F6PR32_CIOIN	H2XP47_CIOIN	ENSCINP00000013090	ENSCINP00000031430	Uncharacterized protein.	G protein gamma domain-containing protein.	0.819
F6PR32_CIOIN	H2XXW5_CIOIN	ENSCINP00000013090	ENSCINP00000034499	Uncharacterized protein.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.819
F6PR32_CIOIN	H2Y1Q1_CIOIN	ENSCINP00000013090	ENSCINP00000035835	Uncharacterized protein.	Uncharacterized protein.	0.548
F6PR32_CIOIN	LOC100182745	ENSCINP00000013090	ENSCINP00000007802	Uncharacterized protein.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1.	0.939
F6PR32_CIOIN	LOC100185742	ENSCINP00000013090	ENSCINP00000035188	Uncharacterized protein.	Guanine nucleotide-binding protein subunit beta-5.	0.885
F6PR32_CIOIN	gi1	ENSCINP00000013090	ENSCINP00000010912	Uncharacterized protein.	G protein alpha subunit Gi splicing variant CiGi1a.	0.548
F6QR00_CIOIN	F6X618_CIOIN	ENSCINP00000013245	ENSCINP00000003619	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	0.995
F6QR00_CIOIN	F6XIG6_CIOIN	ENSCINP00000013245	ENSCINP00000021902	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	RPOL4c domain-containing protein.	0.999