(14 nodes) RHOQ GTPase cycle network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	H2XWC7_CIOIN	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (170 aa)
	LOC100181499	Uncharacterized protein LOC100181499. (166 aa)
	LOC100184804	Uncharacterized protein. (1493 aa)
	H2XKU1_CIOIN	CRIB domain-containing protein. (218 aa)
	H2XKH1_CIOIN	FH2 domain-containing protein. (302 aa)
	LOC100179435	Uncharacterized protein. (393 aa)
	F6WCT6_CIOIN	PDZ domain-containing protein. (347 aa)
	LOC100183094	Ras-related protein rab7-like. (206 aa)
	F6ZNL7_CIOIN	FH2 domain-containing protein. (158 aa)
	LOC100181746	MAGUK p55 subfamily member 7 isoform X1; Belongs to the MAGUK family. (607 aa)
	ci-arfgap-3	Zinc finger protein Ci-ArfGAP-3. (760 aa)
	F6WJF4_CIOIN	C2 domain-containing protein. (464 aa)
	F6YRG2_CIOIN	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (211 aa)
	cdc42	Uncharacterized protein. (95 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6YRG2_CIOIN	cdc42	ENSCINP00000002792	ENSCINP00000001500	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Uncharacterized protein.	0.449
F6ZNL7_CIOIN	cdc42	ENSCINP00000006646	ENSCINP00000001500	FH2 domain-containing protein.	Uncharacterized protein.	0.455
H2XKH1_CIOIN	cdc42	ENSCINP00000030153	ENSCINP00000001500	FH2 domain-containing protein.	Uncharacterized protein.	0.455
LOC100181499	LOC100181746	ENSCINP00000035422	ENSCINP00000005846	Uncharacterized protein LOC100181499.	MAGUK p55 subfamily member 7 isoform X1; Belongs to the MAGUK family.	0.474
LOC100181499	LOC100183094	ENSCINP00000035422	ENSCINP00000015933	Uncharacterized protein LOC100181499.	Ras-related protein rab7-like.	0.427
LOC100181746	LOC100181499	ENSCINP00000005846	ENSCINP00000035422	MAGUK p55 subfamily member 7 isoform X1; Belongs to the MAGUK family.	Uncharacterized protein LOC100181499.	0.474
LOC100181746	cdc42	ENSCINP00000005846	ENSCINP00000001500	MAGUK p55 subfamily member 7 isoform X1; Belongs to the MAGUK family.	Uncharacterized protein.	0.454
LOC100183094	LOC100181499	ENSCINP00000015933	ENSCINP00000035422	Ras-related protein rab7-like.	Uncharacterized protein LOC100181499.	0.427
LOC100183094	cdc42	ENSCINP00000015933	ENSCINP00000001500	Ras-related protein rab7-like.	Uncharacterized protein.	0.495
LOC100184804	cdc42	ENSCINP00000032219	ENSCINP00000001500	Uncharacterized protein.	Uncharacterized protein.	0.517
cdc42	F6YRG2_CIOIN	ENSCINP00000001500	ENSCINP00000002792	Uncharacterized protein.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.449
cdc42	F6ZNL7_CIOIN	ENSCINP00000001500	ENSCINP00000006646	Uncharacterized protein.	FH2 domain-containing protein.	0.455
cdc42	H2XKH1_CIOIN	ENSCINP00000001500	ENSCINP00000030153	Uncharacterized protein.	FH2 domain-containing protein.	0.455
cdc42	LOC100181746	ENSCINP00000001500	ENSCINP00000005846	Uncharacterized protein.	MAGUK p55 subfamily member 7 isoform X1; Belongs to the MAGUK family.	0.454
cdc42	LOC100183094	ENSCINP00000001500	ENSCINP00000015933	Uncharacterized protein.	Ras-related protein rab7-like.	0.495
cdc42	LOC100184804	ENSCINP00000001500	ENSCINP00000032219	Uncharacterized protein.	Uncharacterized protein.	0.517
cdc42	ci-arfgap-3	ENSCINP00000001500	ENSCINP00000005788	Uncharacterized protein.	Zinc finger protein Ci-ArfGAP-3.	0.578
ci-arfgap-3	cdc42	ENSCINP00000005788	ENSCINP00000001500	Zinc finger protein Ci-ArfGAP-3.	Uncharacterized protein.	0.578