57 items (Ciona intestinalis) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

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protein homology

Your Input:
	F7AAS1_CIOIN	Uncharacterized protein. (163 aa)
	LOC100185896	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Belongs to the ferritin family. (164 aa)
	LOC100178177	V-type proton ATPase subunit E-like. (226 aa)
	LOC101242180	Uncharacterized protein. (353 aa)
	H2XT03_CIOIN	Uncharacterized protein. (232 aa)
	H2XT83_CIOIN	Uncharacterized protein. (416 aa)
	H2XW64_CIOIN	Uncharacterized protein. (440 aa)
	H2Y060_CIOIN	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Belongs to the ferritin family. (182 aa)
	LOC100186336	Fe2OG dioxygenase domain-containing protein. (288 aa)
	H2Y1E7_CIOIN	Uncharacterized protein. (427 aa)
	H2XMD0_CIOIN	Uncharacterized protein. (128 aa)
	LOC113474176	kxDL motif-containing protein 1-like. (139 aa)
	H2XSH5_CIOIN	Uncharacterized protein. (438 aa)
	LOC100175978	Proton-coupled folate transporter. (455 aa)
	LOC100181511	S-phase kinase-associated protein 1; Belongs to the SKP1 family. (162 aa)
	F6VXA3_CIOIN	Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily. (533 aa)
	LOC100186125	Glutaredoxin-3. (330 aa)
	F6WTG3_CIOIN	Uncharacterized protein. (473 aa)
	Cytb561	Cytochrome b561 domain-containing protein. (254 aa)
	LOC100176246	Ubiquitin-like domain-containing protein. (78 aa)
	F6YSI6_CIOIN	MFS domain-containing protein. (426 aa)
	L7N0R8_CIOIN	ABC transporter domain-containing protein. (605 aa)
	LOC100177585	ABC transporter domain-containing protein. (220 aa)
	LOC100186035	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (123 aa)
	LOC100176424	V-type proton ATPase subunit D-like. (255 aa)
	F6TYP3_CIOIN	MFS domain-containing protein. (464 aa)
	LOC100184809	V-type proton ATPase catalytic subunit A-like. (619 aa)
	H2XJM7_CIOIN	Uncharacterized protein. (179 aa)
	F6WBQ8_CIOIN	Metallophos domain-containing protein. (211 aa)
	LOC101243220	MFS domain-containing protein. (284 aa)
	F6VJQ1_CIOIN	Uncharacterized protein. (347 aa)
	LOC100176811	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (117 aa)
	LOC104266424	Amidohydro-rel domain-containing protein. (239 aa)
	LOC100185384	ubiquitin-60S ribosomal protein L40. (128 aa)
	LOC100181611	MFS domain-containing protein. (474 aa)
	F6RXW9_CIOIN	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (158 aa)
	F6YHC8_CIOIN	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (379 aa)
	LOC100187083	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (351 aa)
	r27a	R27a protein isoform X1. (155 aa)
	F6PRI9_CIOIN	MFS domain-containing protein. (460 aa)
	LOC100178823	V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (474 aa)
	F6PW28_CIOIN	CULLIN_2 domain-containing protein; Belongs to the cullin family. (778 aa)
	LOC100186335	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (500 aa)
	LOC100176647	Feline leukemia virus subgroup C receptor-related protein 2-like isoform X1. (455 aa)
	LOC100175623	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Belongs to the ferritin family. (248 aa)
	F6Z3T2_CIOIN	TIP120 domain-containing protein. (1277 aa)
	F6X753_CIOIN	ABC transporter domain-containing protein. (660 aa)
	LOC101242403	Uncharacterized protein LOC101242403 isoform X1. (410 aa)
	F6ZJN8_CIOIN	Uncharacterized protein. (381 aa)
	LOC100181913	V-type proton ATPase 21 kDa proteolipid subunit; Belongs to the V-ATPase proteolipid subunit family. (205 aa)
	F6R356_CIOIN	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (849 aa)
	LOC100186938	Cytoplasmic aconitate hydratase; Belongs to the aconitase/IPM isomerase family. (892 aa)
	F6TJQ3_CIOIN	MFS domain-containing protein. (473 aa)
	F7ABV6_CIOIN	Uncharacterized protein; Belongs to the multicopper oxidase family. (1060 aa)
	F6WM68_CIOIN	Uncharacterized protein. (172 aa)
	F6S5Q9_CIOIN	MFS domain-containing protein. (231 aa)
	H2XLR4_CIOIN	Uncharacterized protein. (78 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cytb561	F6VXA3_CIOIN	ENSCINP00000004226	ENSCINP00000003692	Cytochrome b561 domain-containing protein.	Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.	0.407
F6PW28_CIOIN	F6VJQ1_CIOIN	ENSCINP00000013359	ENSCINP00000026820	CULLIN_2 domain-containing protein; Belongs to the cullin family.	Uncharacterized protein.	0.718
F6PW28_CIOIN	F6Z3T2_CIOIN	ENSCINP00000013359	ENSCINP00000015002	CULLIN_2 domain-containing protein; Belongs to the cullin family.	TIP120 domain-containing protein.	0.988
F6PW28_CIOIN	F6ZJN8_CIOIN	ENSCINP00000013359	ENSCINP00000015598	CULLIN_2 domain-containing protein; Belongs to the cullin family.	Uncharacterized protein.	0.742
F6PW28_CIOIN	LOC100176246	ENSCINP00000013359	ENSCINP00000006091	CULLIN_2 domain-containing protein; Belongs to the cullin family.	Ubiquitin-like domain-containing protein.	0.989
F6PW28_CIOIN	LOC100181511	ENSCINP00000013359	ENSCINP00000003403	CULLIN_2 domain-containing protein; Belongs to the cullin family.	S-phase kinase-associated protein 1; Belongs to the SKP1 family.	0.998
F6PW28_CIOIN	LOC100185384	ENSCINP00000013359	ENSCINP00000010307	CULLIN_2 domain-containing protein; Belongs to the cullin family.	ubiquitin-60S ribosomal protein L40.	0.803
F6PW28_CIOIN	LOC100186938	ENSCINP00000013359	ENSCINP00000019416	CULLIN_2 domain-containing protein; Belongs to the cullin family.	Cytoplasmic aconitate hydratase; Belongs to the aconitase/IPM isomerase family.	0.662
F6PW28_CIOIN	r27a	ENSCINP00000013359	ENSCINP00000012037	CULLIN_2 domain-containing protein; Belongs to the cullin family.	R27a protein isoform X1.	0.827
F6R356_CIOIN	F6RXW9_CIOIN	ENSCINP00000018032	ENSCINP00000010648	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.999
F6R356_CIOIN	F6YHC8_CIOIN	ENSCINP00000018032	ENSCINP00000010766	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.998
F6R356_CIOIN	H2XLR4_CIOIN	ENSCINP00000018032	ENSCINP00000030596	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	Uncharacterized protein.	0.996
F6R356_CIOIN	LOC100176424	ENSCINP00000018032	ENSCINP00000009860	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit D-like.	0.989
F6R356_CIOIN	LOC100176811	ENSCINP00000018032	ENSCINP00000026180	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.997
F6R356_CIOIN	LOC100178177	ENSCINP00000018032	ENSCINP00000026021	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit E-like.	0.999
F6R356_CIOIN	LOC100178823	ENSCINP00000018032	ENSCINP00000013243	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system.	0.999
F6R356_CIOIN	LOC100181913	ENSCINP00000018032	ENSCINP00000017036	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase 21 kDa proteolipid subunit; Belongs to the V-ATPase proteolipid subunit family.	0.999
F6R356_CIOIN	LOC100184809	ENSCINP00000018032	ENSCINP00000029917	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase catalytic subunit A-like.	0.999
F6R356_CIOIN	LOC100186035	ENSCINP00000018032	ENSCINP00000008250	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.999
F6R356_CIOIN	LOC100186335	ENSCINP00000018032	ENSCINP00000013764	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.	0.999