(21 nodes) Azathioprine ADME network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	F6XLM7_CIOIN	DALR_1 domain-containing protein. (140 aa)
	H2XSK1_CIOIN	Guanylate kinase-like domain-containing protein. (204 aa)
	H2XYS4_CIOIN	Uncharacterized protein. (237 aa)
	H2XZF5_CIOIN	Uncharacterized protein. (176 aa)
	H2Y0M9_CIOIN	ABC transporter domain-containing protein. (173 aa)
	F6U0U0_CIOIN	Uncharacterized protein. (242 aa)
	LOC100181600	Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (223 aa)
	F6U8W7_CIOIN	Nucleos_tra2_C domain-containing protein. (106 aa)
	F6TJL2_CIOIN	Sodium/nucleoside cotransporter; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family. (518 aa)
	F6TJJ0_CIOIN	Nucleos_tra2_N domain-containing protein. (407 aa)
	F6Y3D6_CIOIN	Uncharacterized protein; Belongs to the GST superfamily. (222 aa)
	F6TFE5_CIOIN	Sodium/nucleoside cotransporter; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family. (573 aa)
	LOC100176897	Uncharacterized protein. (688 aa)
	F6T8N6_CIOIN	Uncharacterized protein. (1291 aa)
	F6WCA3_CIOIN	Uncharacterized protein. (855 aa)
	F6Q5Y8_CIOIN	Uncharacterized protein. (1363 aa)
	LOC100181270	GST C-terminal domain-containing protein. (127 aa)
	F6QDM9_CIOIN	Uncharacterized protein; Belongs to the GST superfamily. (221 aa)
	F6QDM2_CIOIN	GST C-terminal domain-containing protein. (139 aa)
	F6USH9_CIOIN	Inosine-5'-monophosphate dehydrogenase; Belongs to the IMPDH/GMPR family. (384 aa)
	F6USG9_CIOIN	IMPDH domain-containing protein. (193 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6QDM2_CIOIN	F6Y3D6_CIOIN	ENSCINP00000020777	ENSCINP00000009156	GST C-terminal domain-containing protein.	Uncharacterized protein; Belongs to the GST superfamily.	0.652
F6U0U0_CIOIN	F6USH9_CIOIN	ENSCINP00000025606	ENSCINP00000023503	Uncharacterized protein.	Inosine-5'-monophosphate dehydrogenase; Belongs to the IMPDH/GMPR family.	0.911
F6U0U0_CIOIN	H2XZF5_CIOIN	ENSCINP00000025606	ENSCINP00000035039	Uncharacterized protein.	Uncharacterized protein.	0.908
F6U0U0_CIOIN	LOC100176897	ENSCINP00000025606	ENSCINP00000011812	Uncharacterized protein.	Uncharacterized protein.	0.908
F6USG9_CIOIN	F6USH9_CIOIN	ENSCINP00000023504	ENSCINP00000023503	IMPDH domain-containing protein.	Inosine-5'-monophosphate dehydrogenase; Belongs to the IMPDH/GMPR family.	0.951
F6USG9_CIOIN	LOC100176897	ENSCINP00000023504	ENSCINP00000011812	IMPDH domain-containing protein.	Uncharacterized protein.	0.890
F6USH9_CIOIN	F6U0U0_CIOIN	ENSCINP00000023503	ENSCINP00000025606	Inosine-5'-monophosphate dehydrogenase; Belongs to the IMPDH/GMPR family.	Uncharacterized protein.	0.911
F6USH9_CIOIN	F6USG9_CIOIN	ENSCINP00000023503	ENSCINP00000023504	Inosine-5'-monophosphate dehydrogenase; Belongs to the IMPDH/GMPR family.	IMPDH domain-containing protein.	0.951
F6USH9_CIOIN	H2XZF5_CIOIN	ENSCINP00000023503	ENSCINP00000035039	Inosine-5'-monophosphate dehydrogenase; Belongs to the IMPDH/GMPR family.	Uncharacterized protein.	0.911
F6USH9_CIOIN	LOC100176897	ENSCINP00000023503	ENSCINP00000011812	Inosine-5'-monophosphate dehydrogenase; Belongs to the IMPDH/GMPR family.	Uncharacterized protein.	0.991
F6XLM7_CIOIN	LOC100176897	ENSCINP00000026198	ENSCINP00000011812	DALR_1 domain-containing protein.	Uncharacterized protein.	0.890
F6Y3D6_CIOIN	F6QDM2_CIOIN	ENSCINP00000009156	ENSCINP00000020777	Uncharacterized protein; Belongs to the GST superfamily.	GST C-terminal domain-containing protein.	0.652
H2XSK1_CIOIN	LOC100176897	ENSCINP00000032635	ENSCINP00000011812	Guanylate kinase-like domain-containing protein.	Uncharacterized protein.	0.791
H2XSK1_CIOIN	LOC100181600	ENSCINP00000032635	ENSCINP00000006226	Guanylate kinase-like domain-containing protein.	Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.	0.437
H2XYS4_CIOIN	H2Y0M9_CIOIN	ENSCINP00000034808	ENSCINP00000035463	Uncharacterized protein.	ABC transporter domain-containing protein.	0.900
H2XZF5_CIOIN	F6U0U0_CIOIN	ENSCINP00000035039	ENSCINP00000025606	Uncharacterized protein.	Uncharacterized protein.	0.908
H2XZF5_CIOIN	F6USH9_CIOIN	ENSCINP00000035039	ENSCINP00000023503	Uncharacterized protein.	Inosine-5'-monophosphate dehydrogenase; Belongs to the IMPDH/GMPR family.	0.911
H2XZF5_CIOIN	LOC100176897	ENSCINP00000035039	ENSCINP00000011812	Uncharacterized protein.	Uncharacterized protein.	0.908
H2Y0M9_CIOIN	H2XYS4_CIOIN	ENSCINP00000035463	ENSCINP00000034808	ABC transporter domain-containing protein.	Uncharacterized protein.	0.900
LOC100176897	F6U0U0_CIOIN	ENSCINP00000011812	ENSCINP00000025606	Uncharacterized protein.	Uncharacterized protein.	0.908