(31 nodes) GABA receptor activation network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Q69HQ2_CIOIN	Adenylate cyclase; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (439 aa)
	F6YCG7_CIOIN	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1086 aa)
	LOC100180207	G_PROTEIN_RECEP_F3_4 domain-containing protein. (339 aa)
	F7B293_CIOIN	Neur_chan_LBD domain-containing protein. (158 aa)
	LOC100180954	Uncharacterized protein. (383 aa)
	F7AQ62_CIOIN	G_PROTEIN_RECEP_F3_4 domain-containing protein. (769 aa)
	LOC100182745	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. (347 aa)
	F6YG13_CIOIN	Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (446 aa)
	F6YFX5_CIOIN	Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (482 aa)
	F6WKS5_CIOIN	IRK_C domain-containing protein. (113 aa)
	gi1	G protein alpha subunit Gi splicing variant CiGi1a. (354 aa)
	F6Z916_CIOIN	Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (405 aa)
	F6PR32_CIOIN	Uncharacterized protein. (354 aa)
	F6UW56_CIOIN	Uncharacterized protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (947 aa)
	LOC100180789	Uncharacterized protein. (343 aa)
	F6UYT5_CIOIN	AC_N domain-containing protein. (314 aa)
	F6SYS0_CIOIN	G_PROTEIN_RECEP_F3_4 domain-containing protein. (102 aa)
	F6ZIL3_CIOIN	Neur_chan_LBD domain-containing protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (202 aa)
	H2XMZ7_CIOIN	Uncharacterized protein. (163 aa)
	H2XNE8_CIOIN	Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (385 aa)
	H2XNG8_CIOIN	IRK domain-containing protein. (222 aa)
	H2XP47_CIOIN	G protein gamma domain-containing protein. (68 aa)
	LOC100184095	Low molecular weight phosphotyrosine protein phosphatase 1-like. (100 aa)
	H2XQB6_CIOIN	Protein kinase domain-containing protein. (130 aa)
	H2XQR3_CIOIN	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (67 aa)
	H2XS27_CIOIN	Uncharacterized protein. (75 aa)
	H2XVB8_CIOIN	Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (340 aa)
	H2XXW5_CIOIN	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
	LOC100185742	Guanine nucleotide-binding protein subunit beta-5. (376 aa)
	H2Y1Q1_CIOIN	Uncharacterized protein. (356 aa)
	H2Y384_CIOIN	Uncharacterized protein. (77 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6PR32_CIOIN	F6UW56_CIOIN	ENSCINP00000013090	ENSCINP00000014863	Uncharacterized protein.	Uncharacterized protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.468
F6PR32_CIOIN	F6UYT5_CIOIN	ENSCINP00000013090	ENSCINP00000026290	Uncharacterized protein.	AC_N domain-containing protein.	0.438
F6PR32_CIOIN	F6YCG7_CIOIN	ENSCINP00000013090	ENSCINP00000000889	Uncharacterized protein.	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.439
F6PR32_CIOIN	H2XP47_CIOIN	ENSCINP00000013090	ENSCINP00000031430	Uncharacterized protein.	G protein gamma domain-containing protein.	0.819
F6PR32_CIOIN	H2XQR3_CIOIN	ENSCINP00000013090	ENSCINP00000031997	Uncharacterized protein.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.833
F6PR32_CIOIN	H2XXW5_CIOIN	ENSCINP00000013090	ENSCINP00000034499	Uncharacterized protein.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.819
F6PR32_CIOIN	H2Y1Q1_CIOIN	ENSCINP00000013090	ENSCINP00000035835	Uncharacterized protein.	Uncharacterized protein.	0.548
F6PR32_CIOIN	LOC100182745	ENSCINP00000013090	ENSCINP00000007802	Uncharacterized protein.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1.	0.939
F6PR32_CIOIN	LOC100185742	ENSCINP00000013090	ENSCINP00000035188	Uncharacterized protein.	Guanine nucleotide-binding protein subunit beta-5.	0.885
F6PR32_CIOIN	gi1	ENSCINP00000013090	ENSCINP00000010912	Uncharacterized protein.	G protein alpha subunit Gi splicing variant CiGi1a.	0.548
F6SYS0_CIOIN	LOC100182745	ENSCINP00000026303	ENSCINP00000007802	G_PROTEIN_RECEP_F3_4 domain-containing protein.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1.	0.423
F6SYS0_CIOIN	LOC100185742	ENSCINP00000026303	ENSCINP00000035188	G_PROTEIN_RECEP_F3_4 domain-containing protein.	Guanine nucleotide-binding protein subunit beta-5.	0.423
F6UW56_CIOIN	F6PR32_CIOIN	ENSCINP00000014863	ENSCINP00000013090	Uncharacterized protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Uncharacterized protein.	0.468
F6UW56_CIOIN	F6UYT5_CIOIN	ENSCINP00000014863	ENSCINP00000026290	Uncharacterized protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	AC_N domain-containing protein.	0.572
F6UW56_CIOIN	F6YCG7_CIOIN	ENSCINP00000014863	ENSCINP00000000889	Uncharacterized protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.629
F6UW56_CIOIN	H2XQR3_CIOIN	ENSCINP00000014863	ENSCINP00000031997	Uncharacterized protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.645
F6UW56_CIOIN	H2Y1Q1_CIOIN	ENSCINP00000014863	ENSCINP00000035835	Uncharacterized protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Uncharacterized protein.	0.468
F6UW56_CIOIN	H2Y384_CIOIN	ENSCINP00000014863	ENSCINP00000036369	Uncharacterized protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Uncharacterized protein.	0.486
F6UW56_CIOIN	LOC100182745	ENSCINP00000014863	ENSCINP00000007802	Uncharacterized protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1.	0.497
F6UW56_CIOIN	LOC100184095	ENSCINP00000014863	ENSCINP00000031677	Uncharacterized protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Low molecular weight phosphotyrosine protein phosphatase 1-like.	0.418