5 items (Ciona intestinalis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	cdc42	Uncharacterized protein. (95 aa)
	act	Act protein isoform X1. (375 aa)
	LOC100177479	Uncharacterized protein; Belongs to the actin family. (370 aa)
	rhoc	RhoA protein. (193 aa)
	snail	Uncharacterized protein. (584 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC100177479	cdc42	ENSCINP00000006055	ENSCINP00000001500	Uncharacterized protein; Belongs to the actin family.	Uncharacterized protein.	0.591
LOC100177479	rhoc	ENSCINP00000006055	ENSCINP00000006386	Uncharacterized protein; Belongs to the actin family.	RhoA protein.	0.591
act	cdc42	ENSCINP00000001538	ENSCINP00000001500	Act protein isoform X1.	Uncharacterized protein.	0.671
act	rhoc	ENSCINP00000001538	ENSCINP00000006386	Act protein isoform X1.	RhoA protein.	0.704
cdc42	LOC100177479	ENSCINP00000001500	ENSCINP00000006055	Uncharacterized protein.	Uncharacterized protein; Belongs to the actin family.	0.591
cdc42	act	ENSCINP00000001500	ENSCINP00000001538	Uncharacterized protein.	Act protein isoform X1.	0.671
cdc42	rhoc	ENSCINP00000001500	ENSCINP00000006386	Uncharacterized protein.	RhoA protein.	0.621
rhoc	LOC100177479	ENSCINP00000006386	ENSCINP00000006055	RhoA protein.	Uncharacterized protein; Belongs to the actin family.	0.591
rhoc	act	ENSCINP00000006386	ENSCINP00000001538	RhoA protein.	Act protein isoform X1.	0.704
rhoc	cdc42	ENSCINP00000006386	ENSCINP00000001500	RhoA protein.	Uncharacterized protein.	0.621