(16 nodes) (2017) DNA interference-mediated screening of maternal factors in the chordate Oikopleura dioica. network (Ciona intestinalis)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Predicted Interactions

gene neighborhood

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protein homology

Your Input:
	brachyury	Uncharacterized protein. (439 aa)
	LOC100185176	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
	ache	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (618 aa)
	F6Y1Y9_CIOIN	COesterase domain-containing protein. (227 aa)
	LOC100176736	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (452 aa)
	F6V269_CIOIN	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (258 aa)
	LOC100184511	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
	Cibeta-catenin	Uncharacterized protein. (497 aa)
	LOC101242512	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
	LOC100182743	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
	LOC100181688	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
	F6QB29_CIOIN	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
	LOC100178709	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
	F6WU27_CIOIN	COesterase domain-containing protein. (251 aa)
	LOC100186959	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (447 aa)
	H2XZ21_CIOIN	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (220 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cibeta-catenin	brachyury	ENSCINP00000014417	ENSCINP00000001477	Uncharacterized protein.	Uncharacterized protein.	0.526
F6QB29_CIOIN	H2XZ21_CIOIN	ENSCINP00000018124	ENSCINP00000034905	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	0.889
F6QB29_CIOIN	LOC100184511	ENSCINP00000018124	ENSCINP00000014333	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.886
F6QB29_CIOIN	LOC101242512	ENSCINP00000018124	ENSCINP00000015540	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.886
F6V269_CIOIN	F6WU27_CIOIN	ENSCINP00000012936	ENSCINP00000021961	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	COesterase domain-containing protein.	0.900
F6V269_CIOIN	F6Y1Y9_CIOIN	ENSCINP00000012936	ENSCINP00000011711	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	COesterase domain-containing protein.	0.900
F6V269_CIOIN	ache	ENSCINP00000012936	ENSCINP00000009596	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	0.907
F6WU27_CIOIN	F6V269_CIOIN	ENSCINP00000021961	ENSCINP00000012936	COesterase domain-containing protein.	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	0.900
F6WU27_CIOIN	F6Y1Y9_CIOIN	ENSCINP00000021961	ENSCINP00000011711	COesterase domain-containing protein.	COesterase domain-containing protein.	0.905
F6WU27_CIOIN	ache	ENSCINP00000021961	ENSCINP00000009596	COesterase domain-containing protein.	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	0.900
F6Y1Y9_CIOIN	F6V269_CIOIN	ENSCINP00000011711	ENSCINP00000012936	COesterase domain-containing protein.	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	0.900
F6Y1Y9_CIOIN	F6WU27_CIOIN	ENSCINP00000011711	ENSCINP00000021961	COesterase domain-containing protein.	COesterase domain-containing protein.	0.905
F6Y1Y9_CIOIN	ache	ENSCINP00000011711	ENSCINP00000009596	COesterase domain-containing protein.	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	0.900
H2XZ21_CIOIN	F6QB29_CIOIN	ENSCINP00000034905	ENSCINP00000018124	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.889
H2XZ21_CIOIN	LOC100176736	ENSCINP00000034905	ENSCINP00000011748	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.889
H2XZ21_CIOIN	LOC100178709	ENSCINP00000034905	ENSCINP00000018125	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.889
H2XZ21_CIOIN	LOC100181688	ENSCINP00000034905	ENSCINP00000015837	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.889
H2XZ21_CIOIN	LOC100182743	ENSCINP00000034905	ENSCINP00000015767	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.889
H2XZ21_CIOIN	LOC100184511	ENSCINP00000034905	ENSCINP00000014333	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.902
H2XZ21_CIOIN	LOC100185176	ENSCINP00000034905	ENSCINP00000002012	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.889