(11 nodes) (2018) An FGF-driven feed-forward circuit patterns the cardiopharyngeal mesoderm in space and time. network (Ciona intestinalis)

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second shell of interactors

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Known Interactions

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Predicted Interactions

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protein homology

Your Input:
	neurogenin	Transcription factor protein isoform X1. (409 aa)
	notrlc	BHLH domain-containing protein. (297 aa)
	groucho1	Groucho. (847 aa)
	F6YRG2_CIOIN	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (211 aa)
	LOC100177697	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (236 aa)
	cdc42	Uncharacterized protein. (95 aa)
	fgf4/5/6	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (229 aa)
	foxf	Fork-head domain-containing protein. (575 aa)
	mesp	Transcription factor protein. (197 aa)
	LOC100178517	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (142 aa)
	groucho2	Uncharacterized protein. (835 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6YRG2_CIOIN	LOC100177697	ENSCINP00000002792	ENSCINP00000002782	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.494
F6YRG2_CIOIN	LOC100178517	ENSCINP00000002792	ENSCINP00000030917	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.491
F6YRG2_CIOIN	cdc42	ENSCINP00000002792	ENSCINP00000001500	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Uncharacterized protein.	0.449
LOC100177697	F6YRG2_CIOIN	ENSCINP00000002782	ENSCINP00000002792	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.494
LOC100177697	cdc42	ENSCINP00000002782	ENSCINP00000001500	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Uncharacterized protein.	0.533
LOC100178517	F6YRG2_CIOIN	ENSCINP00000030917	ENSCINP00000002792	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.491
cdc42	F6YRG2_CIOIN	ENSCINP00000001500	ENSCINP00000002792	Uncharacterized protein.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.449
cdc42	LOC100177697	ENSCINP00000001500	ENSCINP00000002782	Uncharacterized protein.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.533
fgf4/5/6	foxf	ENSCINP00000001146	ENSCINP00000019099	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fork-head domain-containing protein.	0.408
fgf4/5/6	mesp	ENSCINP00000001146	ENSCINP00000023582	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Transcription factor protein.	0.427
foxf	fgf4/5/6	ENSCINP00000019099	ENSCINP00000001146	Fork-head domain-containing protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.408
foxf	mesp	ENSCINP00000019099	ENSCINP00000023582	Fork-head domain-containing protein.	Transcription factor protein.	0.549
foxf	notrlc	ENSCINP00000019099	ENSCINP00000013512	Fork-head domain-containing protein.	BHLH domain-containing protein.	0.572
mesp	fgf4/5/6	ENSCINP00000023582	ENSCINP00000001146	Transcription factor protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.427
mesp	foxf	ENSCINP00000023582	ENSCINP00000019099	Transcription factor protein.	Fork-head domain-containing protein.	0.549
mesp	neurogenin	ENSCINP00000023582	ENSCINP00000008328	Transcription factor protein.	Transcription factor protein isoform X1.	0.517
mesp	notrlc	ENSCINP00000023582	ENSCINP00000013512	Transcription factor protein.	BHLH domain-containing protein.	0.535
neurogenin	mesp	ENSCINP00000008328	ENSCINP00000023582	Transcription factor protein isoform X1.	Transcription factor protein.	0.517
notrlc	foxf	ENSCINP00000013512	ENSCINP00000019099	BHLH domain-containing protein.	Fork-head domain-containing protein.	0.572
notrlc	mesp	ENSCINP00000013512	ENSCINP00000023582	BHLH domain-containing protein.	Transcription factor protein.	0.535