(21 nodes) Actin network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	F6UC91_CIOIN	Uncharacterized protein; Belongs to the actin family. (326 aa)
	F6QBJ1_CIOIN	Uncharacterized protein. (378 aa)
	LOC100185562	Actin, cytoplasmic-like; Belongs to the actin family. (380 aa)
	F6SCP4_CIOIN	Uncharacterized protein. (377 aa)
	F6SZQ0_CIOIN	Uncharacterized protein; Belongs to the actin family. (375 aa)
	LOC100184134	Actin, muscle-type. (378 aa)
	F6TVZ8_CIOIN	Uncharacterized protein; Belongs to the actin family. (378 aa)
	LOC100176797	Actin, muscle-like. (378 aa)
	LOC100182007	Actin, muscle. (378 aa)
	LOC100183636-2	Actin, muscle. (378 aa)
	LOC100185398	Actin-like protein 6B; Belongs to the actin family. (423 aa)
	F6RD19_CIOIN	Uncharacterized protein; Belongs to the actin family. (404 aa)
	LOC100177479	Uncharacterized protein; Belongs to the actin family. (370 aa)
	F6R7R7_CIOIN	Uncharacterized protein; Belongs to the actin family. (383 aa)
	ENSCINP00000029292	annotation not available (186 aa)
	H2XW16_CIOIN	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (216 aa)
	F6Q662_CIOIN	Uncharacterized protein. (370 aa)
	F6ZTS6_CIOIN	Uncharacterized protein; Belongs to the actin family. (429 aa)
	LOC100183636	Actin, muscle. (378 aa)
	F6R0S4_CIOIN	Uncharacterized protein; Belongs to the actin family. (375 aa)
	act	Act protein isoform X1. (375 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCINP00000029292	F6Q662_CIOIN	ENSCINP00000029292	ENSCINP00000018172	annotation not available	Uncharacterized protein.	0.543
ENSCINP00000029292	F6R7R7_CIOIN	ENSCINP00000029292	ENSCINP00000018335	annotation not available	Uncharacterized protein; Belongs to the actin family.	0.577
ENSCINP00000029292	F6ZTS6_CIOIN	ENSCINP00000029292	ENSCINP00000002709	annotation not available	Uncharacterized protein; Belongs to the actin family.	0.540
ENSCINP00000029292	H2XW16_CIOIN	ENSCINP00000029292	ENSCINP00000033850	annotation not available	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	0.961
ENSCINP00000029292	LOC100176797	ENSCINP00000029292	ENSCINP00000014691	annotation not available	Actin, muscle-like.	0.543
ENSCINP00000029292	LOC100177479	ENSCINP00000029292	ENSCINP00000006055	annotation not available	Uncharacterized protein; Belongs to the actin family.	0.583
ENSCINP00000029292	LOC100182007	ENSCINP00000029292	ENSCINP00000014519	annotation not available	Actin, muscle.	0.543
ENSCINP00000029292	LOC100183636	ENSCINP00000029292	ENSCINP00000002686	annotation not available	Actin, muscle.	0.543
ENSCINP00000029292	LOC100183636-2	ENSCINP00000029292	ENSCINP00000012660	annotation not available	Actin, muscle.	0.543
ENSCINP00000029292	LOC100184134	ENSCINP00000029292	ENSCINP00000015480	annotation not available	Actin, muscle-type.	0.543
ENSCINP00000029292	LOC100185398	ENSCINP00000029292	ENSCINP00000010732	annotation not available	Actin-like protein 6B; Belongs to the actin family.	0.503
F6Q662_CIOIN	ENSCINP00000029292	ENSCINP00000018172	ENSCINP00000029292	Uncharacterized protein.	annotation not available	0.543
F6Q662_CIOIN	F6R7R7_CIOIN	ENSCINP00000018172	ENSCINP00000018335	Uncharacterized protein.	Uncharacterized protein; Belongs to the actin family.	0.578
F6Q662_CIOIN	F6TVZ8_CIOIN	ENSCINP00000018172	ENSCINP00000015449	Uncharacterized protein.	Uncharacterized protein; Belongs to the actin family.	0.440
F6Q662_CIOIN	F6ZTS6_CIOIN	ENSCINP00000018172	ENSCINP00000002709	Uncharacterized protein.	Uncharacterized protein; Belongs to the actin family.	0.815
F6Q662_CIOIN	H2XW16_CIOIN	ENSCINP00000018172	ENSCINP00000033850	Uncharacterized protein.	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	0.633
F6Q662_CIOIN	LOC100176797	ENSCINP00000018172	ENSCINP00000014691	Uncharacterized protein.	Actin, muscle-like.	0.543
F6Q662_CIOIN	LOC100177479	ENSCINP00000018172	ENSCINP00000006055	Uncharacterized protein.	Uncharacterized protein; Belongs to the actin family.	0.580
F6Q662_CIOIN	LOC100182007	ENSCINP00000018172	ENSCINP00000014519	Uncharacterized protein.	Actin, muscle.	0.543
F6Q662_CIOIN	LOC100183636	ENSCINP00000018172	ENSCINP00000002686	Uncharacterized protein.	Actin, muscle.	0.543