(45 nodes) Lysine degradation network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC100186221	Uncharacterized protein. (269 aa)
	F6Q7A6_CIOIN	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (475 aa)
	F6RSF3_CIOIN	SET domain-containing protein. (227 aa)
	LOC100186995	enoyl-CoA hydratase, mitochondrial; Belongs to the enoyl-CoA hydratase/isomerase family. (291 aa)
	F6VYY7_CIOIN	Uncharacterized protein. (589 aa)
	LOC100184970	Hydroxylysine kinase isoform X1. (341 aa)
	LOC100177845	acetyl-CoA acetyltransferase, mitochondrial-like; Belongs to the thiolase-like superfamily. Thiolase family. (413 aa)
	LOC100180564	Peroxisomal bifunctional enzyme-like isoform X1. (486 aa)
	LOC100182913	Peroxisomal bifunctional enzyme; Belongs to the enoyl-CoA hydratase/isomerase family. (731 aa)
	F6PK80_CIOIN	Aminotran_1_2 domain-containing protein. (432 aa)
	F7BBK7_CIOIN	DAO domain-containing protein. (124 aa)
	smyd1	Uncharacterized protein. (474 aa)
	LOC100187496	Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial-like. (309 aa)
	LOC100177042	Uncharacterized protein LOC100177042 isoform X1. (404 aa)
	LOC100181980	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (725 aa)
	LOC100182755	Aldehyde dehydrogenase family 16 member A1-like; Belongs to the aldehyde dehydrogenase family. (827 aa)
	LOC100184635	Uncharacterized protein. (401 aa)
	LOC100179624	Histone-lysine N-methyltransferase SMYD3. (430 aa)
	L7N0S9_CIOIN	Aminotran_1_2 domain-containing protein. (219 aa)
	F7AZV0_CIOIN	Lipoyl-binding domain-containing protein. (391 aa)
	LOC100175707	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (522 aa)
	LOC100184485	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (542 aa)
	F6TG24_CIOIN	Fe2OG dioxygenase domain-containing protein. (735 aa)
	F7AA62_CIOIN	Uncharacterized protein. (270 aa)
	F6WR85_CIOIN	Dihydrolipoyl dehydrogenase. (509 aa)
	F7AGV8_CIOIN	Uncharacterized protein. (323 aa)
	F6TKV3_CIOIN	Transket_pyr domain-containing protein. (781 aa)
	F6ZU97_CIOIN	Uncharacterized protein. (460 aa)
	F6XGM8_CIOIN	APH domain-containing protein. (157 aa)
	LOC100183557	DAO domain-containing protein. (312 aa)
	LOC100175450	DAO domain-containing protein. (299 aa)
	F6YW02_CIOIN	DAO domain-containing protein. (363 aa)
	F6UBA5_CIOIN	Uncharacterized protein. (763 aa)
	F6PQ59_CIOIN	Uncharacterized protein. (137 aa)
	F6SQS1_CIOIN	SET domain-containing protein. (192 aa)
	F6XZR7_CIOIN	Uncharacterized protein. (543 aa)
	F6YAT7_CIOIN	Uncharacterized protein. (220 aa)
	F6WVH9_CIOIN	Amine oxidase. (396 aa)
	H2XK62_CIOIN	Histone-lysine N-methyltransferase, H3 lysine-79 specific. (256 aa)
	LOC100183994	Procollagen galactosyltransferase 1 isoform X1. (594 aa)
	H2XTH1_CIOIN	Uncharacterized protein. (145 aa)
	H2XXF5_CIOIN	Uncharacterized protein. (153 aa)
	H2XY01_CIOIN	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (466 aa)
	H2Y092_CIOIN	Uncharacterized protein. (263 aa)
	H2Y3I0_CIOIN	APH domain-containing protein. (192 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6PK80_CIOIN	F6TKV3_CIOIN	ENSCINP00000006285	ENSCINP00000019191	Aminotran_1_2 domain-containing protein.	Transket_pyr domain-containing protein.	0.919
F6PK80_CIOIN	F6WR85_CIOIN	ENSCINP00000006285	ENSCINP00000016324	Aminotran_1_2 domain-containing protein.	Dihydrolipoyl dehydrogenase.	0.900
F6PK80_CIOIN	F7AZV0_CIOIN	ENSCINP00000006285	ENSCINP00000014023	Aminotran_1_2 domain-containing protein.	Lipoyl-binding domain-containing protein.	0.908
F6PK80_CIOIN	L7N0S9_CIOIN	ENSCINP00000006285	ENSCINP00000013525	Aminotran_1_2 domain-containing protein.	Aminotran_1_2 domain-containing protein.	0.906
F6PK80_CIOIN	LOC100184485	ENSCINP00000006285	ENSCINP00000015438	Aminotran_1_2 domain-containing protein.	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	0.916
F6PQ59_CIOIN	F6TG24_CIOIN	ENSCINP00000025385	ENSCINP00000016152	Uncharacterized protein.	Fe2OG dioxygenase domain-containing protein.	0.900
F6PQ59_CIOIN	F6UBA5_CIOIN	ENSCINP00000025385	ENSCINP00000024984	Uncharacterized protein.	Uncharacterized protein.	0.900
F6PQ59_CIOIN	F6VYY7_CIOIN	ENSCINP00000025385	ENSCINP00000003156	Uncharacterized protein.	Uncharacterized protein.	0.900
F6PQ59_CIOIN	F6XZR7_CIOIN	ENSCINP00000025385	ENSCINP00000025830	Uncharacterized protein.	Uncharacterized protein.	0.900
F6PQ59_CIOIN	F7AA62_CIOIN	ENSCINP00000025385	ENSCINP00000016213	Uncharacterized protein.	Uncharacterized protein.	0.900
F6PQ59_CIOIN	F7AGV8_CIOIN	ENSCINP00000025385	ENSCINP00000017639	Uncharacterized protein.	Uncharacterized protein.	0.900
F6PQ59_CIOIN	H2XK62_CIOIN	ENSCINP00000025385	ENSCINP00000030044	Uncharacterized protein.	Histone-lysine N-methyltransferase, H3 lysine-79 specific.	0.900
F6PQ59_CIOIN	H2XXF5_CIOIN	ENSCINP00000025385	ENSCINP00000034339	Uncharacterized protein.	Uncharacterized protein.	0.900
F6PQ59_CIOIN	LOC100179624	ENSCINP00000025385	ENSCINP00000013431	Uncharacterized protein.	Histone-lysine N-methyltransferase SMYD3.	0.900
F6PQ59_CIOIN	LOC100186221	ENSCINP00000025385	ENSCINP00000000048	Uncharacterized protein.	Uncharacterized protein.	0.900
F6PQ59_CIOIN	smyd1	ENSCINP00000025385	ENSCINP00000006865	Uncharacterized protein.	Uncharacterized protein.	0.900
F6Q7A6_CIOIN	F7AZV0_CIOIN	ENSCINP00000001020	ENSCINP00000014023	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Lipoyl-binding domain-containing protein.	0.495
F6Q7A6_CIOIN	H2XY01_CIOIN	ENSCINP00000001020	ENSCINP00000034535	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.903
F6Q7A6_CIOIN	H2Y092_CIOIN	ENSCINP00000001020	ENSCINP00000035326	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Uncharacterized protein.	0.916
F6Q7A6_CIOIN	LOC100177042	ENSCINP00000001020	ENSCINP00000008524	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Uncharacterized protein LOC100177042 isoform X1.	0.916