(53 nodes) Various types of N-glycan biosynthesis network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC100177471	Mannosyltransferase. (499 aa)
	LOC100180226	Alpha-1,3/1,6-mannosyltransferase ALG2. (437 aa)
	LOC100181785	UDP-N-acetylglucosamine transferase subunit ALG13 homolog. (162 aa)
	Fut8	Alpha-(1,6)-fucosyltransferase; Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans. Belongs to the glycosyltransferase 23 family. (524 aa)
	LOC104265699	GT23 domain-containing protein; Belongs to the glycosyltransferase 23 family. (504 aa)
	LOC100184901	Uncharacterized protein. (330 aa)
	F6ZPY6_CIOIN	Uncharacterized protein. (327 aa)
	F6XS27_CIOIN	Uncharacterized protein. (128 aa)
	F6X2H2_CIOIN	Uncharacterized protein. (323 aa)
	LOC100187449	Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A isoform X1. (354 aa)
	LOC100181376	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (463 aa)
	LOC100185960	Beta-1,4-galactosyltransferase 1. (372 aa)
	F6TSZ2_CIOIN	GT23 domain-containing protein; Belongs to the glycosyltransferase 23 family. (202 aa)
	LOC100187142	Beta-hexosaminidase. (535 aa)
	LOC100178428	Beta-hexosaminidase. (538 aa)
	F7BMU6_CIOIN	Uncharacterized protein. (403 aa)
	F7AB40_CIOIN	Uncharacterized protein. (375 aa)
	F7B9A3_CIOIN	Uncharacterized protein; Belongs to the glycosyltransferase 23 family. (451 aa)
	F7A738_CIOIN	Uncharacterized protein. (247 aa)
	LOC100178567	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across t [...] (438 aa)
	LOC100177361	Uncharacterized protein. (710 aa)
	F6YR40_CIOIN	Uncharacterized protein. (344 aa)
	F6ZQX2_CIOIN	GT23 domain-containing protein; Belongs to the glycosyltransferase 23 family. (423 aa)
	LOC100180827	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (400 aa)
	F6XTL0_CIOIN	Uncharacterized protein. (310 aa)
	LOC100184175	GT23 domain-containing protein; Belongs to the glycosyltransferase 23 family. (558 aa)
	LOC100183416	Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A-like. (356 aa)
	F6XM91_CIOIN	Uncharacterized protein; Belongs to the glycosyltransferase 23 family. (220 aa)
	F6S3Q7_CIOIN	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (630 aa)
	F6QIE7_CIOIN	Carbohydrate sulfotransferase. (275 aa)
	F6QH11_CIOIN	Carbohydrate sulfotransferase. (341 aa)
	LOC100181252-2	Uncharacterized protein. (413 aa)
	F6TM93_CIOIN	Uncharacterized protein. (216 aa)
	F7AWP7_CIOIN	GT23 domain-containing protein; Belongs to the glycosyltransferase 23 family. (564 aa)
	F6TBU9_CIOIN	GT23 domain-containing protein; Belongs to the glycosyltransferase 23 family. (375 aa)
	LOC100181865	Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A-like. (504 aa)
	LOC100186610	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...] (114 aa)
	F6TEP2_CIOIN	GT23 domain-containing protein; Belongs to the glycosyltransferase 23 family. (200 aa)
	LOC100180498	Uncharacterized protein. (483 aa)
	F6RMI2_CIOIN	Alpha-mannosidase. (1158 aa)
	LOC101242566	UDP-N-acetylglucosamine transferase subunit ALG14 homolog. (203 aa)
	F7A8D3_CIOIN	GT23 domain-containing protein; Belongs to the glycosyltransferase 23 family. (365 aa)
	F7BHZ3_CIOIN	Uncharacterized protein. (230 aa)
	F6ZBI9_CIOIN	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (458 aa)
	F6PJB8_CIOIN	Uncharacterized protein. (219 aa)
	H2XN21_CIOIN	Uncharacterized protein. (423 aa)
	H2XQC4_CIOIN	GT23 domain-containing protein; Belongs to the glycosyltransferase 23 family. (489 aa)
	H2XR08_CIOIN	Mannosyltransferase. (529 aa)
	B4galt	Uncharacterized protein. (413 aa)
	H2XYH4_CIOIN	Uncharacterized protein; Belongs to the glycosyltransferase 23 family. (405 aa)
	H2XYI9_CIOIN	Uncharacterized protein; Belongs to the glycosyltransferase 23 family. (422 aa)
	H2Y0J1_CIOIN	GT23 domain-containing protein; Belongs to the glycosyltransferase 23 family. (573 aa)
	fut8	Alpha-(1,6)-fucosyltransferase; Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans. Belongs to the glycosyltransferase 23 family. (560 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B4galt	F6TBU9_CIOIN	ENSCINP00000033045	ENSCINP00000022020	Uncharacterized protein.	GT23 domain-containing protein; Belongs to the glycosyltransferase 23 family.	0.657
B4galt	F6TEP2_CIOIN	ENSCINP00000033045	ENSCINP00000023592	Uncharacterized protein.	GT23 domain-containing protein; Belongs to the glycosyltransferase 23 family.	0.650
B4galt	F6TSZ2_CIOIN	ENSCINP00000033045	ENSCINP00000008864	Uncharacterized protein.	GT23 domain-containing protein; Belongs to the glycosyltransferase 23 family.	0.657
B4galt	F6XM91_CIOIN	ENSCINP00000033045	ENSCINP00000017718	Uncharacterized protein.	Uncharacterized protein; Belongs to the glycosyltransferase 23 family.	0.657
B4galt	F6XS27_CIOIN	ENSCINP00000033045	ENSCINP00000005156	Uncharacterized protein.	Uncharacterized protein.	0.650
B4galt	F6ZQX2_CIOIN	ENSCINP00000033045	ENSCINP00000011696	Uncharacterized protein.	GT23 domain-containing protein; Belongs to the glycosyltransferase 23 family.	0.657
B4galt	F7A8D3_CIOIN	ENSCINP00000033045	ENSCINP00000025738	Uncharacterized protein.	GT23 domain-containing protein; Belongs to the glycosyltransferase 23 family.	0.657
B4galt	F7AWP7_CIOIN	ENSCINP00000033045	ENSCINP00000021831	Uncharacterized protein.	GT23 domain-containing protein; Belongs to the glycosyltransferase 23 family.	0.657
B4galt	F7B9A3_CIOIN	ENSCINP00000033045	ENSCINP00000010121	Uncharacterized protein.	Uncharacterized protein; Belongs to the glycosyltransferase 23 family.	0.657
B4galt	F7BHZ3_CIOIN	ENSCINP00000033045	ENSCINP00000026387	Uncharacterized protein.	Uncharacterized protein.	0.655
B4galt	Fut8	ENSCINP00000033045	ENSCINP00000002948	Uncharacterized protein.	Alpha-(1,6)-fucosyltransferase; Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans. Belongs to the glycosyltransferase 23 family.	0.657
B4galt	H2XQC4_CIOIN	ENSCINP00000033045	ENSCINP00000031858	Uncharacterized protein.	GT23 domain-containing protein; Belongs to the glycosyltransferase 23 family.	0.657
B4galt	H2XYH4_CIOIN	ENSCINP00000033045	ENSCINP00000034708	Uncharacterized protein.	Uncharacterized protein; Belongs to the glycosyltransferase 23 family.	0.657
B4galt	H2XYI9_CIOIN	ENSCINP00000033045	ENSCINP00000034723	Uncharacterized protein.	Uncharacterized protein; Belongs to the glycosyltransferase 23 family.	0.657
B4galt	H2Y0J1_CIOIN	ENSCINP00000033045	ENSCINP00000035425	Uncharacterized protein.	GT23 domain-containing protein; Belongs to the glycosyltransferase 23 family.	0.657
B4galt	LOC100184175	ENSCINP00000033045	ENSCINP00000016632	Uncharacterized protein.	GT23 domain-containing protein; Belongs to the glycosyltransferase 23 family.	0.657
B4galt	LOC104265699	ENSCINP00000033045	ENSCINP00000002954	Uncharacterized protein.	GT23 domain-containing protein; Belongs to the glycosyltransferase 23 family.	0.657
B4galt	fut8	ENSCINP00000033045	ENSCINP00000035521	Uncharacterized protein.	Alpha-(1,6)-fucosyltransferase; Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans. Belongs to the glycosyltransferase 23 family.	0.657
F6PJB8_CIOIN	H2XR08_CIOIN	ENSCINP00000028736	ENSCINP00000032092	Uncharacterized protein.	Mannosyltransferase.	0.922
F6PJB8_CIOIN	LOC100177361	ENSCINP00000028736	ENSCINP00000010932	Uncharacterized protein.	Uncharacterized protein.	0.449