(18 nodes) Glycosaminoglycan biosynthesis - heparan sulfate / heparin network (Ciona intestinalis)

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Your Input:
	uglcat1	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family. (340 aa)
	xt	Xylosyltransferase; Catalyzes the first step in biosynthesis of glycosaminoglycan. Transfers D-xylose from UDP-D-xylose to specific serine residues of the core protein. Initial enzyme in the biosynthesis of chondroitin sulfate and dermatan sulfate proteoglycans in fibroblasts and chondrocytes; Belongs to the glycosyltransferase 14 family. XylT subfamily. (848 aa)
	F6WFB4_CIOIN	Uncharacterized protein. (809 aa)
	F6Q0W6_CIOIN	Uncharacterized protein; Belongs to the glycosyltransferase 47 family. (753 aa)
	F6ZVY0_CIOIN	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family. (296 aa)
	LOC100182982	Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. (382 aa)
	F6TU56_CIOIN	Uncharacterized protein. (259 aa)
	F7AVD2_CIOIN	Glyco_transf_7C domain-containing protein. (136 aa)
	LOC101242339	Sulfotransferase; Belongs to the sulfotransferase 1 family. (432 aa)
	H2XK38_CIOIN	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family. (308 aa)
	H2XK55_CIOIN	C5-epim_C domain-containing protein. (572 aa)
	H2XKU8_CIOIN	Sulfotransferase; Belongs to the sulfotransferase 1 family. (322 aa)
	b3galt6	Hexosyltransferase. (327 aa)
	H2XTR7_CIOIN	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family. (278 aa)
	H2XW04_CIOIN	Uncharacterized protein; Belongs to the glycosyltransferase 47 family. (660 aa)
	H2XWZ5_CIOIN	Uncharacterized protein. (346 aa)
	uglcat2l	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family. (285 aa)
	H2Y2M6_CIOIN	C5-epim_C domain-containing protein. (568 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6Q0W6_CIOIN	F6WFB4_CIOIN	ENSCINP00000013346	ENSCINP00000012314	Uncharacterized protein; Belongs to the glycosyltransferase 47 family.	Uncharacterized protein.	0.633
F6Q0W6_CIOIN	H2XKU8_CIOIN	ENSCINP00000013346	ENSCINP00000030280	Uncharacterized protein; Belongs to the glycosyltransferase 47 family.	Sulfotransferase; Belongs to the sulfotransferase 1 family.	0.481
F6Q0W6_CIOIN	H2XW04_CIOIN	ENSCINP00000013346	ENSCINP00000033838	Uncharacterized protein; Belongs to the glycosyltransferase 47 family.	Uncharacterized protein; Belongs to the glycosyltransferase 47 family.	0.997
F6Q0W6_CIOIN	H2XWZ5_CIOIN	ENSCINP00000013346	ENSCINP00000034179	Uncharacterized protein; Belongs to the glycosyltransferase 47 family.	Uncharacterized protein.	0.547
F6Q0W6_CIOIN	LOC100182982	ENSCINP00000013346	ENSCINP00000016267	Uncharacterized protein; Belongs to the glycosyltransferase 47 family.	Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.	0.531
F6Q0W6_CIOIN	uglcat1	ENSCINP00000013346	ENSCINP00000006544	Uncharacterized protein; Belongs to the glycosyltransferase 47 family.	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family.	0.454
F6TU56_CIOIN	F7AVD2_CIOIN	ENSCINP00000022886	ENSCINP00000023056	Uncharacterized protein.	Glyco_transf_7C domain-containing protein.	0.904
F6TU56_CIOIN	b3galt6	ENSCINP00000022886	ENSCINP00000032620	Uncharacterized protein.	Hexosyltransferase.	0.945
F6TU56_CIOIN	uglcat1	ENSCINP00000022886	ENSCINP00000006544	Uncharacterized protein.	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family.	0.476
F6TU56_CIOIN	xt	ENSCINP00000022886	ENSCINP00000009027	Uncharacterized protein.	Xylosyltransferase; Catalyzes the first step in biosynthesis of glycosaminoglycan. Transfers D-xylose from UDP-D-xylose to specific serine residues of the core protein. Initial enzyme in the biosynthesis of chondroitin sulfate and dermatan sulfate proteoglycans in fibroblasts and chondrocytes; Belongs to the glycosyltransferase 14 family. XylT subfamily.	0.938
F6WFB4_CIOIN	F6Q0W6_CIOIN	ENSCINP00000012314	ENSCINP00000013346	Uncharacterized protein.	Uncharacterized protein; Belongs to the glycosyltransferase 47 family.	0.633
F6WFB4_CIOIN	H2XK55_CIOIN	ENSCINP00000012314	ENSCINP00000030037	Uncharacterized protein.	C5-epim_C domain-containing protein.	0.940
F6WFB4_CIOIN	H2XW04_CIOIN	ENSCINP00000012314	ENSCINP00000033838	Uncharacterized protein.	Uncharacterized protein; Belongs to the glycosyltransferase 47 family.	0.550
F6WFB4_CIOIN	H2XWZ5_CIOIN	ENSCINP00000012314	ENSCINP00000034179	Uncharacterized protein.	Uncharacterized protein.	0.574
F6WFB4_CIOIN	H2Y2M6_CIOIN	ENSCINP00000012314	ENSCINP00000036161	Uncharacterized protein.	C5-epim_C domain-containing protein.	0.940
F6WFB4_CIOIN	LOC100182982	ENSCINP00000012314	ENSCINP00000016267	Uncharacterized protein.	Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.	0.557
F6ZVY0_CIOIN	b3galt6	ENSCINP00000014443	ENSCINP00000032620	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family.	Hexosyltransferase.	0.915
F7AVD2_CIOIN	F6TU56_CIOIN	ENSCINP00000023056	ENSCINP00000022886	Glyco_transf_7C domain-containing protein.	Uncharacterized protein.	0.904
F7AVD2_CIOIN	b3galt6	ENSCINP00000023056	ENSCINP00000032620	Glyco_transf_7C domain-containing protein.	Hexosyltransferase.	0.945
F7AVD2_CIOIN	uglcat1	ENSCINP00000023056	ENSCINP00000006544	Glyco_transf_7C domain-containing protein.	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family.	0.476