(20 nodes) Nicotinate and nicotinamide metabolism network (Ciona intestinalis)

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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Predicted Interactions

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Your Input:
	F6Y110_CIOIN	Uncharacterized protein. (269 aa)
	Sir2-d	Deacetylase sirtuin-type domain-containing protein. (91 aa)
	F6SKP5_CIOIN	Uncharacterized protein; Belongs to the 5'-nucleotidase family. (462 aa)
	LOC100181174	Uncharacterized protein. (403 aa)
	LOC100185509	Cytosolic 5'-nucleotidase 1A. (361 aa)
	LOC100185251-2	Zinc finger protein. (339 aa)
	LOC100177271	Uncharacterized protein. (454 aa)
	LOC100183021	Cytosolic purine 5'-nucleotidase isoform X4. (548 aa)
	F6Z6J2_CIOIN	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (296 aa)
	LOC100177202	Uncharacterized protein. (1029 aa)
	F7BJC2_CIOIN	Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. (703 aa)
	F6XHJ8_CIOIN	NUC domain-containing protein. (475 aa)
	F7APS6_CIOIN	Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (478 aa)
	LOC100185848	Deacetylase sirtuin-type domain-containing protein. (357 aa)
	F6TT30_CIOIN	CTP_transf_like domain-containing protein. (242 aa)
	F7A5R9_CIOIN	Uncharacterized protein. (342 aa)
	LOC778889	Deacetylase sirtuin-type domain-containing protein. (319 aa)
	F6SLD6_CIOIN	Deacetylase sirtuin-type domain-containing protein. (737 aa)
	sir2-a	NAD-dependent protein deacetylase; Belongs to the sirtuin family. Class I subfamily. (363 aa)
	H2XWF2_CIOIN	NAD-dependent protein deacylase; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. (278 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6SKP5_CIOIN	F6TT30_CIOIN	ENSCINP00000008305	ENSCINP00000024093	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	CTP_transf_like domain-containing protein.	0.971
F6SKP5_CIOIN	F6XHJ8_CIOIN	ENSCINP00000008305	ENSCINP00000021920	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	NUC domain-containing protein.	0.907
F6SKP5_CIOIN	F6Z6J2_CIOIN	ENSCINP00000008305	ENSCINP00000016539	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.	0.979
F6SKP5_CIOIN	F7A5R9_CIOIN	ENSCINP00000008305	ENSCINP00000027289	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	Uncharacterized protein.	0.901
F6SKP5_CIOIN	F7APS6_CIOIN	ENSCINP00000008305	ENSCINP00000022147	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.	0.922
F6SKP5_CIOIN	F7BJC2_CIOIN	ENSCINP00000008305	ENSCINP00000017941	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family.	0.738
F6SKP5_CIOIN	LOC100177271	ENSCINP00000008305	ENSCINP00000012890	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	Uncharacterized protein.	0.979
F6SKP5_CIOIN	LOC100181174	ENSCINP00000008305	ENSCINP00000010957	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	Uncharacterized protein.	0.730
F6SKP5_CIOIN	LOC100183021	ENSCINP00000008305	ENSCINP00000015119	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	Cytosolic purine 5'-nucleotidase isoform X4.	0.911
F6SKP5_CIOIN	LOC100185509	ENSCINP00000008305	ENSCINP00000011780	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	Cytosolic 5'-nucleotidase 1A.	0.920
F6SLD6_CIOIN	F6TT30_CIOIN	ENSCINP00000027486	ENSCINP00000024093	Deacetylase sirtuin-type domain-containing protein.	CTP_transf_like domain-containing protein.	0.922
F6SLD6_CIOIN	F6XHJ8_CIOIN	ENSCINP00000027486	ENSCINP00000021920	Deacetylase sirtuin-type domain-containing protein.	NUC domain-containing protein.	0.900
F6SLD6_CIOIN	F6Z6J2_CIOIN	ENSCINP00000027486	ENSCINP00000016539	Deacetylase sirtuin-type domain-containing protein.	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.	0.926
F6SLD6_CIOIN	F7BJC2_CIOIN	ENSCINP00000027486	ENSCINP00000017941	Deacetylase sirtuin-type domain-containing protein.	Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family.	0.944
F6SLD6_CIOIN	LOC100177202	ENSCINP00000027486	ENSCINP00000016569	Deacetylase sirtuin-type domain-containing protein.	Uncharacterized protein.	0.900
F6SLD6_CIOIN	LOC100177271	ENSCINP00000027486	ENSCINP00000012890	Deacetylase sirtuin-type domain-containing protein.	Uncharacterized protein.	0.912
F6SLD6_CIOIN	LOC100181174	ENSCINP00000027486	ENSCINP00000010957	Deacetylase sirtuin-type domain-containing protein.	Uncharacterized protein.	0.926
F6SLD6_CIOIN	LOC100185251-2	ENSCINP00000027486	ENSCINP00000012226	Deacetylase sirtuin-type domain-containing protein.	Zinc finger protein.	0.541
F6SLD6_CIOIN	LOC100185848	ENSCINP00000027486	ENSCINP00000023359	Deacetylase sirtuin-type domain-containing protein.	Deacetylase sirtuin-type domain-containing protein.	0.724
F6SLD6_CIOIN	LOC778889	ENSCINP00000027486	ENSCINP00000027422	Deacetylase sirtuin-type domain-containing protein.	Deacetylase sirtuin-type domain-containing protein.	0.498