(29 nodes) Metabolism of xenobiotics by cytochrome P450 network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC100184425	Glutathione S-transferase 1-like. (199 aa)
	LOC100187122	Aflatoxin B1 aldehyde reductase member 2-like. (328 aa)
	LOC100182061	Uncharacterized protein; Belongs to the GST superfamily. (202 aa)
	LOC100186038	Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase-like. (349 aa)
	F7AGK5_CIOIN	Uncharacterized protein. (144 aa)
	F7AE92_CIOIN	Uncharacterized protein; Belongs to the GST superfamily. (211 aa)
	LOC100179151	Glutathione S-transferase theta-1-like. (216 aa)
	LOC100184961	Glutathione S-transferase 1-1-like isoform X1; Belongs to the GST superfamily. (226 aa)
	F6WRW7_CIOIN	Uncharacterized protein; Belongs to the GST superfamily. (231 aa)
	F7BDX5_CIOIN	Uncharacterized protein; Belongs to the GST superfamily. (204 aa)
	F6Y3D6_CIOIN	Uncharacterized protein; Belongs to the GST superfamily. (222 aa)
	LOC100183297	Glutathione S-transferase omega-1. (216 aa)
	F6V9K6_CIOIN	Uncharacterized protein. (224 aa)
	F7AV59_CIOIN	Uncharacterized protein; Belongs to the GST superfamily. (250 aa)
	LOC100176187	Uncharacterized protein; Belongs to the GST superfamily. (244 aa)
	F6YVH4_CIOIN	Uncharacterized protein; Belongs to the cytochrome P450 family. (535 aa)
	F6VQ32_CIOIN	Uncharacterized protein; Belongs to the GST superfamily. (198 aa)
	LOC100178265	Glutathione S-transferase 1; Belongs to the GST superfamily. (224 aa)
	adh3	S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (377 aa)
	LOC100179669	Glutathione S-transferase omega-1-like; Belongs to the GST superfamily. (245 aa)
	F6RAJ1_CIOIN	Uncharacterized protein; Belongs to the GST superfamily. (254 aa)
	F6QDM2_CIOIN	GST C-terminal domain-containing protein. (139 aa)
	LOC100178653	Glutathione S-transferase Mu 1-like. (225 aa)
	LOC100177239	Hematopoietic prostaglandin D synthase; Belongs to the GST superfamily. (197 aa)
	LOC100186966	Uncharacterized protein. (202 aa)
	F7A0D6_CIOIN	Epoxide hydrolase. (453 aa)
	LOC100186348	Glutathione S-transferase kappa. (225 aa)
	LOC100182286	Carbonyl reductase [NADPH] 1-like; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (275 aa)
	H2XYY3_CIOIN	Uncharacterized protein; Belongs to the cytochrome P450 family. (525 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6QDM2_CIOIN	F6RAJ1_CIOIN	ENSCINP00000020777	ENSCINP00000020024	GST C-terminal domain-containing protein.	Uncharacterized protein; Belongs to the GST superfamily.	0.710
F6QDM2_CIOIN	F6V9K6_CIOIN	ENSCINP00000020777	ENSCINP00000010811	GST C-terminal domain-containing protein.	Uncharacterized protein.	0.710
F6QDM2_CIOIN	F6VQ32_CIOIN	ENSCINP00000020777	ENSCINP00000012909	GST C-terminal domain-containing protein.	Uncharacterized protein; Belongs to the GST superfamily.	0.731
F6QDM2_CIOIN	F6WRW7_CIOIN	ENSCINP00000020777	ENSCINP00000004318	GST C-terminal domain-containing protein.	Uncharacterized protein; Belongs to the GST superfamily.	0.710
F6QDM2_CIOIN	F6Y3D6_CIOIN	ENSCINP00000020777	ENSCINP00000009156	GST C-terminal domain-containing protein.	Uncharacterized protein; Belongs to the GST superfamily.	0.652
F6QDM2_CIOIN	F6YVH4_CIOIN	ENSCINP00000020777	ENSCINP00000012842	GST C-terminal domain-containing protein.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.654
F6QDM2_CIOIN	F7A0D6_CIOIN	ENSCINP00000020777	ENSCINP00000029372	GST C-terminal domain-containing protein.	Epoxide hydrolase.	0.678
F6QDM2_CIOIN	F7AE92_CIOIN	ENSCINP00000020777	ENSCINP00000002443	GST C-terminal domain-containing protein.	Uncharacterized protein; Belongs to the GST superfamily.	0.710
F6QDM2_CIOIN	F7AGK5_CIOIN	ENSCINP00000020777	ENSCINP00000002062	GST C-terminal domain-containing protein.	Uncharacterized protein.	0.679
F6QDM2_CIOIN	F7AV59_CIOIN	ENSCINP00000020777	ENSCINP00000011374	GST C-terminal domain-containing protein.	Uncharacterized protein; Belongs to the GST superfamily.	0.745
F6QDM2_CIOIN	F7BDX5_CIOIN	ENSCINP00000020777	ENSCINP00000009038	GST C-terminal domain-containing protein.	Uncharacterized protein; Belongs to the GST superfamily.	0.731
F6QDM2_CIOIN	H2XYY3_CIOIN	ENSCINP00000020777	ENSCINP00000034867	GST C-terminal domain-containing protein.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.654
F6QDM2_CIOIN	LOC100176187	ENSCINP00000020777	ENSCINP00000011385	GST C-terminal domain-containing protein.	Uncharacterized protein; Belongs to the GST superfamily.	0.745
F6QDM2_CIOIN	LOC100177239	ENSCINP00000020777	ENSCINP00000025179	GST C-terminal domain-containing protein.	Hematopoietic prostaglandin D synthase; Belongs to the GST superfamily.	0.731
F6QDM2_CIOIN	LOC100178265	ENSCINP00000020777	ENSCINP00000017032	GST C-terminal domain-containing protein.	Glutathione S-transferase 1; Belongs to the GST superfamily.	0.710
F6QDM2_CIOIN	LOC100178653	ENSCINP00000020777	ENSCINP00000022076	GST C-terminal domain-containing protein.	Glutathione S-transferase Mu 1-like.	0.701
F6QDM2_CIOIN	LOC100179151	ENSCINP00000020777	ENSCINP00000003049	GST C-terminal domain-containing protein.	Glutathione S-transferase theta-1-like.	0.770
F6QDM2_CIOIN	LOC100179669	ENSCINP00000020777	ENSCINP00000017658	GST C-terminal domain-containing protein.	Glutathione S-transferase omega-1-like; Belongs to the GST superfamily.	0.745
F6QDM2_CIOIN	LOC100182061	ENSCINP00000020777	ENSCINP00000001243	GST C-terminal domain-containing protein.	Uncharacterized protein; Belongs to the GST superfamily.	0.731
F6QDM2_CIOIN	LOC100183297	ENSCINP00000020777	ENSCINP00000009433	GST C-terminal domain-containing protein.	Glutathione S-transferase omega-1.	0.738