(19 nodes) Protein export network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC100182362	Signal recognition particle subunit SRP72; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane; Belongs to the SRP72 family. (694 aa)
	LOC100178515	Probable signal peptidase complex subunit 2. (184 aa)
	LOC100179323	J domain-containing protein. (737 aa)
	F6YGD1_CIOIN	Signal recognition particle subunit SRP68; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane; Belongs to the SRP68 family. (594 aa)
	LOC100184140	Signal recognition particle 14 kDa protein-like. (119 aa)
	F6VR17_CIOIN	Uncharacterized protein. (269 aa)
	LOC100178586	Translocation protein SEC62-like isoform X2. (345 aa)
	SRP54	Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. (501 aa)
	F6T7B1_CIOIN	Uncharacterized protein. (328 aa)
	F6Q601_CIOIN	SRP54 domain-containing protein. (642 aa)
	F6ZM86_CIOIN	Plug_translocon domain-containing protein. (454 aa)
	LOC100186609	Uncharacterized protein; Belongs to the heat shock protein 70 family. (671 aa)
	LOC101242470	Uncharacterized protein; Belongs to the heat shock protein 70 family. (659 aa)
	LOC100184661	Signal peptidase complex subunit 3. (177 aa)
	LOC108950015	Mitochondrial inner membrane protease subunit 2-like. (217 aa)
	LOC100183780	Signal peptidase complex catalytic subunit SEC11. (179 aa)
	LOC100175466	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (97 aa)
	sec61g	Protein transport protein Sec61 subunit gamma; Necessary for protein translocation in the endoplasmic reticulum. (68 aa)
	H2XVS6_CIOIN	Uncharacterized protein. (272 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6Q601_CIOIN	F6T7B1_CIOIN	ENSCINP00000018178	ENSCINP00000015718	SRP54 domain-containing protein.	Uncharacterized protein.	0.524
F6Q601_CIOIN	F6VR17_CIOIN	ENSCINP00000018178	ENSCINP00000012664	SRP54 domain-containing protein.	Uncharacterized protein.	0.996
F6Q601_CIOIN	F6YGD1_CIOIN	ENSCINP00000018178	ENSCINP00000008744	SRP54 domain-containing protein.	Signal recognition particle subunit SRP68; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane; Belongs to the SRP68 family.	0.938
F6Q601_CIOIN	F6ZM86_CIOIN	ENSCINP00000018178	ENSCINP00000018963	SRP54 domain-containing protein.	Plug_translocon domain-containing protein.	0.861
F6Q601_CIOIN	H2XVS6_CIOIN	ENSCINP00000018178	ENSCINP00000033760	SRP54 domain-containing protein.	Uncharacterized protein.	0.524
F6Q601_CIOIN	LOC100175466	ENSCINP00000018178	ENSCINP00000029828	SRP54 domain-containing protein.	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.	0.447
F6Q601_CIOIN	LOC100178515	ENSCINP00000018178	ENSCINP00000006110	SRP54 domain-containing protein.	Probable signal peptidase complex subunit 2.	0.482
F6Q601_CIOIN	LOC100178586	ENSCINP00000018178	ENSCINP00000013540	SRP54 domain-containing protein.	Translocation protein SEC62-like isoform X2.	0.540
F6Q601_CIOIN	LOC100179323	ENSCINP00000018178	ENSCINP00000006134	SRP54 domain-containing protein.	J domain-containing protein.	0.732
F6Q601_CIOIN	LOC100182362	ENSCINP00000018178	ENSCINP00000004932	SRP54 domain-containing protein.	Signal recognition particle subunit SRP72; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane; Belongs to the SRP72 family.	0.943
F6Q601_CIOIN	LOC100184140	ENSCINP00000018178	ENSCINP00000010612	SRP54 domain-containing protein.	Signal recognition particle 14 kDa protein-like.	0.820
F6Q601_CIOIN	SRP54	ENSCINP00000018178	ENSCINP00000015156	SRP54 domain-containing protein.	Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily.	0.994
F6Q601_CIOIN	sec61g	ENSCINP00000018178	ENSCINP00000030766	SRP54 domain-containing protein.	Protein transport protein Sec61 subunit gamma; Necessary for protein translocation in the endoplasmic reticulum.	0.548
F6T7B1_CIOIN	F6Q601_CIOIN	ENSCINP00000015718	ENSCINP00000018178	Uncharacterized protein.	SRP54 domain-containing protein.	0.524
F6T7B1_CIOIN	F6ZM86_CIOIN	ENSCINP00000015718	ENSCINP00000018963	Uncharacterized protein.	Plug_translocon domain-containing protein.	0.907
F6T7B1_CIOIN	H2XVS6_CIOIN	ENSCINP00000015718	ENSCINP00000033760	Uncharacterized protein.	Uncharacterized protein.	0.929
F6T7B1_CIOIN	SRP54	ENSCINP00000015718	ENSCINP00000015156	Uncharacterized protein.	Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily.	0.538
F6VR17_CIOIN	F6Q601_CIOIN	ENSCINP00000012664	ENSCINP00000018178	Uncharacterized protein.	SRP54 domain-containing protein.	0.996
F6VR17_CIOIN	F6YGD1_CIOIN	ENSCINP00000012664	ENSCINP00000008744	Uncharacterized protein.	Signal recognition particle subunit SRP68; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane; Belongs to the SRP68 family.	0.914
F6VR17_CIOIN	F6ZM86_CIOIN	ENSCINP00000012664	ENSCINP00000018963	Uncharacterized protein.	Plug_translocon domain-containing protein.	0.653