(19 nodes) One carbon pool by folate, and L-serine biosynthetic process network (Branchiostoma floridae)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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Predicted Interactions

gene neighborhood

gene fusions

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Your Input:
	C3XPI2_BRAFL	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (686 aa)
	C3XQB2_BRAFL	Uncharacterized protein. (291 aa)
	C3XSQ5_BRAFL	SHMT domain-containing protein. (406 aa)
	C3Y126_BRAFL	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (509 aa)
	C3Y298_BRAFL	Uncharacterized protein. (1033 aa)
	C3YSM4_BRAFL	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (323 aa)
	C3YVL6_BRAFL	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. (379 aa)
	C3YXK9_BRAFL	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. (1018 aa)
	C3YY11_BRAFL	Uncharacterized protein. (187 aa)
	C3Z0P2_BRAFL	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (185 aa)
	C3Z0U0_BRAFL	Phosphoserine aminotransferase. (368 aa)
	C3Z3N4_BRAFL	Uncharacterized protein. (934 aa)
	C3Z8L4_BRAFL	Uncharacterized protein. (541 aa)
	C3ZB58_BRAFL	Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (172 aa)
	C3ZLY2_BRAFL	Uncharacterized protein. (312 aa)
	C3ZVI5_BRAFL	Carrier domain-containing protein; Belongs to the aldehyde dehydrogenase family. (936 aa)
	C3ZXJ5_BRAFL	Thymidylat_synt domain-containing protein. (294 aa)
	C3ZZF6_BRAFL	Uncharacterized protein. (1318 aa)
	C3ZZU2_BRAFL	THF_DHG_CYH_C domain-containing protein. (755 aa)

Your Current Organism:

Branchiostoma floridae

NCBI taxonomy Id: 7739
Other names: Amphioxus floridae, B. floridae, Florida lancelet

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C3XPI2_BRAFL	C3XQB2_BRAFL	C3XPI2	C3XQB2	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	Uncharacterized protein.	0.996
C3XPI2_BRAFL	C3XSQ5_BRAFL	C3XPI2	C3XSQ5	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	SHMT domain-containing protein.	0.949
C3XPI2_BRAFL	C3Y126_BRAFL	C3XPI2	C3Y126	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.994
C3XPI2_BRAFL	C3Y298_BRAFL	C3XPI2	C3Y298	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	Uncharacterized protein.	0.574
C3XPI2_BRAFL	C3YSM4_BRAFL	C3XPI2	C3YSM4	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.513
C3XPI2_BRAFL	C3YVL6_BRAFL	C3XPI2	C3YVL6	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	0.972
C3XPI2_BRAFL	C3YXK9_BRAFL	C3XPI2	C3YXK9	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	0.874
C3XPI2_BRAFL	C3Z0P2_BRAFL	C3XPI2	C3Z0P2	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	0.710
C3XPI2_BRAFL	C3Z3N4_BRAFL	C3XPI2	C3Z3N4	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	Uncharacterized protein.	0.972
C3XPI2_BRAFL	C3Z8L4_BRAFL	C3XPI2	C3Z8L4	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	Uncharacterized protein.	0.754
C3XPI2_BRAFL	C3ZB58_BRAFL	C3XPI2	C3ZB58	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family.	0.971
C3XPI2_BRAFL	C3ZXJ5_BRAFL	C3XPI2	C3ZXJ5	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	Thymidylat_synt domain-containing protein.	0.971
C3XPI2_BRAFL	C3ZZF6_BRAFL	C3XPI2	C3ZZF6	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	Uncharacterized protein.	0.967
C3XPI2_BRAFL	C3ZZU2_BRAFL	C3XPI2	C3ZZU2	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	THF_DHG_CYH_C domain-containing protein.	0.735
C3XQB2_BRAFL	C3XPI2_BRAFL	C3XQB2	C3XPI2	Uncharacterized protein.	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	0.996
C3XQB2_BRAFL	C3XSQ5_BRAFL	C3XQB2	C3XSQ5	Uncharacterized protein.	SHMT domain-containing protein.	0.974
C3XQB2_BRAFL	C3Y126_BRAFL	C3XQB2	C3Y126	Uncharacterized protein.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.997
C3XQB2_BRAFL	C3Y298_BRAFL	C3XQB2	C3Y298	Uncharacterized protein.	Uncharacterized protein.	0.935
C3XQB2_BRAFL	C3YSM4_BRAFL	C3XQB2	C3YSM4	Uncharacterized protein.	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.513
C3XQB2_BRAFL	C3YVL6_BRAFL	C3XQB2	C3YVL6	Uncharacterized protein.	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	0.993