(11 nodes) One carbon pool by folate network (Branchiostoma floridae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	C3XPI2_BRAFL	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (686 aa)
	C3XQB2_BRAFL	Uncharacterized protein. (291 aa)
	C3Y126_BRAFL	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (509 aa)
	C3YVL6_BRAFL	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. (379 aa)
	C3Z0P2_BRAFL	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (185 aa)
	C3Z3N4_BRAFL	Uncharacterized protein. (934 aa)
	C3Z8L4_BRAFL	Uncharacterized protein. (541 aa)
	C3ZB58_BRAFL	Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (172 aa)
	C3ZVI5_BRAFL	Carrier domain-containing protein; Belongs to the aldehyde dehydrogenase family. (936 aa)
	C3ZXJ5_BRAFL	Thymidylat_synt domain-containing protein. (294 aa)
	C3ZZF6_BRAFL	Uncharacterized protein. (1318 aa)

Your Current Organism:

Branchiostoma floridae

NCBI taxonomy Id: 7739
Other names: Amphioxus floridae, B. floridae, Florida lancelet

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C3XPI2_BRAFL	C3XQB2_BRAFL	C3XPI2	C3XQB2	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	Uncharacterized protein.	0.996
C3XPI2_BRAFL	C3Y126_BRAFL	C3XPI2	C3Y126	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.994
C3XPI2_BRAFL	C3YVL6_BRAFL	C3XPI2	C3YVL6	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	0.972
C3XPI2_BRAFL	C3Z0P2_BRAFL	C3XPI2	C3Z0P2	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	0.710
C3XPI2_BRAFL	C3Z3N4_BRAFL	C3XPI2	C3Z3N4	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	Uncharacterized protein.	0.972
C3XPI2_BRAFL	C3Z8L4_BRAFL	C3XPI2	C3Z8L4	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	Uncharacterized protein.	0.754
C3XPI2_BRAFL	C3ZB58_BRAFL	C3XPI2	C3ZB58	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family.	0.971
C3XPI2_BRAFL	C3ZXJ5_BRAFL	C3XPI2	C3ZXJ5	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	Thymidylat_synt domain-containing protein.	0.971
C3XPI2_BRAFL	C3ZZF6_BRAFL	C3XPI2	C3ZZF6	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	Uncharacterized protein.	0.967
C3XQB2_BRAFL	C3XPI2_BRAFL	C3XQB2	C3XPI2	Uncharacterized protein.	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	0.996
C3XQB2_BRAFL	C3Y126_BRAFL	C3XQB2	C3Y126	Uncharacterized protein.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.997
C3XQB2_BRAFL	C3YVL6_BRAFL	C3XQB2	C3YVL6	Uncharacterized protein.	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	0.993
C3XQB2_BRAFL	C3Z0P2_BRAFL	C3XQB2	C3Z0P2	Uncharacterized protein.	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	0.613
C3XQB2_BRAFL	C3Z3N4_BRAFL	C3XQB2	C3Z3N4	Uncharacterized protein.	Uncharacterized protein.	0.994
C3XQB2_BRAFL	C3Z8L4_BRAFL	C3XQB2	C3Z8L4	Uncharacterized protein.	Uncharacterized protein.	0.996
C3XQB2_BRAFL	C3ZB58_BRAFL	C3XQB2	C3ZB58	Uncharacterized protein.	Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family.	0.980
C3XQB2_BRAFL	C3ZVI5_BRAFL	C3XQB2	C3ZVI5	Uncharacterized protein.	Carrier domain-containing protein; Belongs to the aldehyde dehydrogenase family.	0.938
C3XQB2_BRAFL	C3ZXJ5_BRAFL	C3XQB2	C3ZXJ5	Uncharacterized protein.	Thymidylat_synt domain-containing protein.	0.996
C3XQB2_BRAFL	C3ZZF6_BRAFL	C3XQB2	C3ZZF6	Uncharacterized protein.	Uncharacterized protein.	0.984
C3Y126_BRAFL	C3XPI2_BRAFL	C3Y126	C3XPI2	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	0.994