(40 nodes) Base-excision repair, and Nonhomologous end joining complex network (Branchiostoma floridae)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	C3XPG8_BRAFL	DNA ligase. (928 aa)
	C3XQC7_BRAFL	POLXc domain-containing protein. (186 aa)
	C3XS08_BRAFL	Uncharacterized protein. (644 aa)
	C3Y2J9_BRAFL	ENDO3c domain-containing protein. (401 aa)
	C3Y3U5_BRAFL	Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (303 aa)
	C3Y7M2_BRAFL	Uncharacterized protein; Belongs to the peptidase C19 family. (1318 aa)
	C3Y959_BRAFL	Uncharacterized protein. (256 aa)
	C3YF62_BRAFL	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (311 aa)
	C3YF64_BRAFL	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (4388 aa)
	C3YF65_BRAFL	Uncharacterized protein. (488 aa)
	C3YIK5_BRAFL	Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. (425 aa)
	C3YIK7_BRAFL	ENDO3c domain-containing protein. (161 aa)
	C3YIS5_BRAFL	BRCT domain-containing protein; Belongs to the DNA polymerase type-X family. (430 aa)
	C3YJ28_BRAFL	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (510 aa)
	C3YKZ1_BRAFL	Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (264 aa)
	C3YPF6_BRAFL	LisH domain-containing protein. (1288 aa)
	C3YPJ3_BRAFL	DRMBL domain-containing protein. (387 aa)
	C3YT49_BRAFL	Uncharacterized protein. (471 aa)
	C3YW92_BRAFL	DNA_binding_1 domain-containing protein. (166 aa)
	C3YWT8_BRAFL	Endo/exonuclease/phosphatase domain-containing protein. (278 aa)
	C3YX76_BRAFL	DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family. (272 aa)
	C3YXZ3_BRAFL	Uncharacterized protein. (114 aa)
	C3YYJ6_BRAFL	TOP4c domain-containing protein. (1181 aa)
	C3YZ01_BRAFL	DNA ligase. (793 aa)
	C3YZ80_BRAFL	Uncharacterized protein. (894 aa)
	C3Z1F8_BRAFL	Ku domain-containing protein. (613 aa)
	C3Z5F7_BRAFL	Enkurin domain-containing protein. (285 aa)
	C3Z7H4_BRAFL	ENDO3c domain-containing protein. (239 aa)
	C3Z7U8_BRAFL	AP_endonuc_2 domain-containing protein. (326 aa)
	C3Z7U9_BRAFL	AP_endonuc_2 domain-containing protein. (119 aa)
	C3Z8D4_BRAFL	Uncharacterized protein. (114 aa)
	C3ZA89_BRAFL	DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family. (561 aa)
	C3ZC83_BRAFL	Endo/exonuclease/phosphatase domain-containing protein. (403 aa)
	C3ZFB4_BRAFL	HIT domain-containing protein. (183 aa)
	C3ZGW7_BRAFL	Uncharacterized protein. (175 aa)
	C3ZLG4_BRAFL	XRCC1_N domain-containing protein. (590 aa)
	C3ZR24_BRAFL	Uncharacterized protein. (130 aa)
	C3ZSM7_BRAFL	Ku domain-containing protein. (716 aa)
	C3ZV88_BRAFL	TOPEUc domain-containing protein. (299 aa)
	C3ZZJ5_BRAFL	FHA_2 domain-containing protein. (427 aa)

Your Current Organism:

Branchiostoma floridae

NCBI taxonomy Id: 7739
Other names: Amphioxus floridae, B. floridae, Florida lancelet

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C3XPG8_BRAFL	C3XQC7_BRAFL	C3XPG8	C3XQC7	DNA ligase.	POLXc domain-containing protein.	0.897
C3XPG8_BRAFL	C3XS08_BRAFL	C3XPG8	C3XS08	DNA ligase.	Uncharacterized protein.	0.993
C3XPG8_BRAFL	C3Y2J9_BRAFL	C3XPG8	C3Y2J9	DNA ligase.	ENDO3c domain-containing protein.	0.532
C3XPG8_BRAFL	C3YF62_BRAFL	C3XPG8	C3YF62	DNA ligase.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.529
C3XPG8_BRAFL	C3YF64_BRAFL	C3XPG8	C3YF64	DNA ligase.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.529
C3XPG8_BRAFL	C3YF65_BRAFL	C3XPG8	C3YF65	DNA ligase.	Uncharacterized protein.	0.494
C3XPG8_BRAFL	C3YIS5_BRAFL	C3XPG8	C3YIS5	DNA ligase.	BRCT domain-containing protein; Belongs to the DNA polymerase type-X family.	0.579
C3XPG8_BRAFL	C3YJ28_BRAFL	C3XPG8	C3YJ28	DNA ligase.	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	0.690
C3XPG8_BRAFL	C3YPJ3_BRAFL	C3XPG8	C3YPJ3	DNA ligase.	DRMBL domain-containing protein.	0.401
C3XPG8_BRAFL	C3YT49_BRAFL	C3XPG8	C3YT49	DNA ligase.	Uncharacterized protein.	0.808
C3XPG8_BRAFL	C3YWT8_BRAFL	C3XPG8	C3YWT8	DNA ligase.	Endo/exonuclease/phosphatase domain-containing protein.	0.523
C3XPG8_BRAFL	C3YX76_BRAFL	C3XPG8	C3YX76	DNA ligase.	DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family.	0.740
C3XPG8_BRAFL	C3YXZ3_BRAFL	C3XPG8	C3YXZ3	DNA ligase.	Uncharacterized protein.	0.523
C3XPG8_BRAFL	C3Z1F8_BRAFL	C3XPG8	C3Z1F8	DNA ligase.	Ku domain-containing protein.	0.917
C3XPG8_BRAFL	C3Z5F7_BRAFL	C3XPG8	C3Z5F7	DNA ligase.	Enkurin domain-containing protein.	0.579
C3XPG8_BRAFL	C3Z7H4_BRAFL	C3XPG8	C3Z7H4	DNA ligase.	ENDO3c domain-containing protein.	0.439
C3XPG8_BRAFL	C3Z8D4_BRAFL	C3XPG8	C3Z8D4	DNA ligase.	Uncharacterized protein.	0.523
C3XPG8_BRAFL	C3ZA89_BRAFL	C3XPG8	C3ZA89	DNA ligase.	DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family.	0.557
C3XPG8_BRAFL	C3ZFB4_BRAFL	C3XPG8	C3ZFB4	DNA ligase.	HIT domain-containing protein.	0.706
C3XPG8_BRAFL	C3ZGW7_BRAFL	C3XPG8	C3ZGW7	DNA ligase.	Uncharacterized protein.	0.528