(52 nodes) TNF signaling, and Downstream TCR signaling network (Branchiostoma floridae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	C3XQ28_BRAFL	RING-type domain-containing protein. (545 aa)
	C3XTU5_BRAFL	Uncharacterized protein. (2572 aa)
	C3XTV7_BRAFL	Protein kinase domain-containing protein. (473 aa)
	C3XU40_BRAFL	Uncharacterized protein. (2155 aa)
	C3Y0R3_BRAFL	Uncharacterized protein. (532 aa)
	C3Y1H0_BRAFL	Uncharacterized protein. (271 aa)
	C3Y6F9_BRAFL	TIR domain-containing protein. (139 aa)
	C3Y755_BRAFL	Uncharacterized protein. (255 aa)
	C3Y7A9_BRAFL	Protein kinase domain-containing protein. (739 aa)
	C3Y7F3_BRAFL	Protein kinase domain-containing protein. (702 aa)
	C3Y8G6_BRAFL	Death domain-containing protein. (1064 aa)
	C3YDV1_BRAFL	Protein kinase domain-containing protein. (1102 aa)
	C3YEQ1_BRAFL	Uncharacterized protein; Belongs to the peptidase C14A family. (476 aa)
	C3YFB5_BRAFL	Protein kinase domain-containing protein. (1155 aa)
	C3YFT5_BRAFL	Protein kinase domain-containing protein. (755 aa)
	C3YI94_BRAFL	Uncharacterized protein. (101 aa)
	C3YPE7_BRAFL	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (447 aa)
	C3YPU4_BRAFL	CCHC NOA-type domain-containing protein. (873 aa)
	C3YV23_BRAFL	Uncharacterized protein. (872 aa)
	C3YV25_BRAFL	Uncharacterized protein. (498 aa)
	C3YWJ6_BRAFL	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (96 aa)
	C3Z3A4_BRAFL	Uncharacterized protein. (676 aa)
	C3Z4P8_BRAFL	Uncharacterized protein. (195 aa)
	C3Z5N3_BRAFL	RING-type domain-containing protein. (358 aa)
	C3Z5V2_BRAFL	RING-type domain-containing protein. (395 aa)
	C3Z725_BRAFL	PPM-type phosphatase domain-containing protein. (534 aa)
	C3Z8U0_BRAFL	Uncharacterized protein. (572 aa)
	C3Z946_BRAFL	Uncharacterized protein. (310 aa)
	C3Z9S3_BRAFL	RING-type domain-containing protein. (370 aa)
	C3ZDH3_BRAFL	RING-type domain-containing protein. (861 aa)
	C3ZE87_BRAFL	Protein kinase domain-containing protein. (659 aa)
	C3ZG34_BRAFL	Uncharacterized protein. (552 aa)
	C3ZG35_BRAFL	Uncharacterized protein. (658 aa)
	C3ZG37_BRAFL	Uncharacterized protein. (631 aa)
	C3ZG38_BRAFL	MATH domain-containing protein. (373 aa)
	C3ZG39_BRAFL	Uncharacterized protein. (549 aa)
	C3ZG40_BRAFL	Uncharacterized protein. (503 aa)
	C3ZGY7_BRAFL	Uncharacterized protein. (298 aa)
	C3ZH16_BRAFL	Uncharacterized protein. (473 aa)
	C3ZH58_BRAFL	Protein kinase domain-containing protein. (1633 aa)
	C3ZLL1_BRAFL	Uncharacterized protein. (597 aa)
	C3ZLY3_BRAFL	Uncharacterized protein. (2226 aa)
	C3ZN65_BRAFL	Uncharacterized protein. (147 aa)
	C3ZNP8_BRAFL	Protein kinase domain-containing protein. (634 aa)
	C3ZP99_BRAFL	Death domain-containing protein. (195 aa)
	C3ZPZ7_BRAFL	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (451 aa)
	C3ZQC7_BRAFL	Uncharacterized protein. (424 aa)
	C3ZQU2_BRAFL	Uncharacterized protein; Belongs to the peptidase C14A family. (739 aa)
	C3ZXZ8_BRAFL	Death domain-containing protein. (298 aa)
	C3ZYU7_BRAFL	MATH domain-containing protein. (107 aa)
	C3ZYU8_BRAFL	Uncharacterized protein. (1550 aa)
	C3ZZM6_BRAFL	Uncharacterized protein. (197 aa)

Your Current Organism:

Branchiostoma floridae

NCBI taxonomy Id: 7739
Other names: Amphioxus floridae, B. floridae, Florida lancelet

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C3XQ28_BRAFL	C3XU40_BRAFL	C3XQ28	C3XU40	RING-type domain-containing protein.	Uncharacterized protein.	0.403
C3XQ28_BRAFL	C3Z5V2_BRAFL	C3XQ28	C3Z5V2	RING-type domain-containing protein.	RING-type domain-containing protein.	0.900
C3XQ28_BRAFL	C3Z725_BRAFL	C3XQ28	C3Z725	RING-type domain-containing protein.	PPM-type phosphatase domain-containing protein.	0.481
C3XTU5_BRAFL	C3Y8G6_BRAFL	C3XTU5	C3Y8G6	Uncharacterized protein.	Death domain-containing protein.	0.647
C3XTU5_BRAFL	C3ZQC7_BRAFL	C3XTU5	C3ZQC7	Uncharacterized protein.	Uncharacterized protein.	0.450
C3XTV7_BRAFL	C3Y8G6_BRAFL	C3XTV7	C3Y8G6	Protein kinase domain-containing protein.	Death domain-containing protein.	0.647
C3XTV7_BRAFL	C3ZQC7_BRAFL	C3XTV7	C3ZQC7	Protein kinase domain-containing protein.	Uncharacterized protein.	0.450
C3XU40_BRAFL	C3XQ28_BRAFL	C3XU40	C3XQ28	Uncharacterized protein.	RING-type domain-containing protein.	0.403
C3XU40_BRAFL	C3Y7A9_BRAFL	C3XU40	C3Y7A9	Uncharacterized protein.	Protein kinase domain-containing protein.	0.872
C3XU40_BRAFL	C3Y8G6_BRAFL	C3XU40	C3Y8G6	Uncharacterized protein.	Death domain-containing protein.	0.813
C3XU40_BRAFL	C3YFT5_BRAFL	C3XU40	C3YFT5	Uncharacterized protein.	Protein kinase domain-containing protein.	0.608
C3XU40_BRAFL	C3YPU4_BRAFL	C3XU40	C3YPU4	Uncharacterized protein.	CCHC NOA-type domain-containing protein.	0.576
C3XU40_BRAFL	C3YV23_BRAFL	C3XU40	C3YV23	Uncharacterized protein.	Uncharacterized protein.	0.970
C3XU40_BRAFL	C3YV25_BRAFL	C3XU40	C3YV25	Uncharacterized protein.	Uncharacterized protein.	0.999
C3XU40_BRAFL	C3Z3A4_BRAFL	C3XU40	C3Z3A4	Uncharacterized protein.	Uncharacterized protein.	0.415
C3XU40_BRAFL	C3Z5N3_BRAFL	C3XU40	C3Z5N3	Uncharacterized protein.	RING-type domain-containing protein.	0.444
C3XU40_BRAFL	C3Z5V2_BRAFL	C3XU40	C3Z5V2	Uncharacterized protein.	RING-type domain-containing protein.	0.444
C3XU40_BRAFL	C3Z725_BRAFL	C3XU40	C3Z725	Uncharacterized protein.	PPM-type phosphatase domain-containing protein.	0.545
C3XU40_BRAFL	C3Z9S3_BRAFL	C3XU40	C3Z9S3	Uncharacterized protein.	RING-type domain-containing protein.	0.444
C3XU40_BRAFL	C3ZDH3_BRAFL	C3XU40	C3ZDH3	Uncharacterized protein.	RING-type domain-containing protein.	0.406