(30 nodes) Transcription initiation from RNA polymerase II promoter network (Branchiostoma floridae)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	C3YX15_BRAFL	Peptidase_M1 domain-containing protein. (1059 aa)
	C4A0W1_BRAFL	CYCLIN domain-containing protein; Belongs to the cyclin family. (326 aa)
	C3ZT09_BRAFL	CYCLIN domain-containing protein; Belongs to the cyclin family. (326 aa)
	C3ZQZ0_BRAFL	Uncharacterized protein. (172 aa)
	C3ZFY4_BRAFL	CBFD_NFYB_HMF domain-containing protein. (173 aa)
	C3ZEY7_BRAFL	TAF domain-containing protein. (653 aa)
	C3ZCP1_BRAFL	TFIIB-type domain-containing protein. (319 aa)
	C3ZC47_BRAFL	BTP domain-containing protein. (286 aa)
	C3Z898_BRAFL	General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (249 aa)
	C3Z5Q6_BRAFL	Uncharacterized protein. (71 aa)
	C3Z4S1_BRAFL	TAF domain-containing protein. (444 aa)
	C3Z2E0_BRAFL	HTH TFE/IIEalpha-type domain-containing protein. (429 aa)
	C3YXI9_BRAFL	Peptidase_M1 domain-containing protein. (995 aa)
	C3YW09_BRAFL	TAFII28 domain-containing protein. (106 aa)
	C3YVD4_BRAFL	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (298 aa)
	C3YQI6_BRAFL	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (534 aa)
	C3YLI3_BRAFL	PHD-type domain-containing protein. (1052 aa)
	C3YEN1_BRAFL	TAFH domain-containing protein. (590 aa)
	C3YEN0_BRAFL	Uncharacterized protein. (721 aa)
	C3YBY7_BRAFL	Uncharacterized protein. (798 aa)
	C3Y3A3_BRAFL	Uncharacterized protein. (2008 aa)
	C3Y0I0_BRAFL	Uncharacterized protein. (311 aa)
	C3XWK5_BRAFL	TAFII55_N domain-containing protein. (381 aa)
	C3XU46_BRAFL	TAFH domain-containing protein. (78 aa)
	C3XU45_BRAFL	TAF4 domain-containing protein. (58 aa)
	C3XU44_BRAFL	TAF4 domain-containing protein. (195 aa)
	C3XTJ3_BRAFL	TFIID_20kDa domain-containing protein. (184 aa)
	C3XRA2_BRAFL	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
	C3XPX8_BRAFL	RPOL4c domain-containing protein. (142 aa)
	C3XPP3_BRAFL	Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (136 aa)

Your Current Organism:

Branchiostoma floridae

NCBI taxonomy Id: 7739
Other names: Amphioxus floridae, B. floridae, Florida lancelet

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C3XPP3_BRAFL	C3XPX8_BRAFL	C3XPP3	C3XPX8	Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family.	RPOL4c domain-containing protein.	0.805
C3XPP3_BRAFL	C3XRA2_BRAFL	C3XPP3	C3XRA2	Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	0.841
C3XPP3_BRAFL	C3XTJ3_BRAFL	C3XPP3	C3XTJ3	Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family.	TFIID_20kDa domain-containing protein.	0.999
C3XPP3_BRAFL	C3XU44_BRAFL	C3XPP3	C3XU44	Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family.	TAF4 domain-containing protein.	0.929
C3XPP3_BRAFL	C3XU45_BRAFL	C3XPP3	C3XU45	Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family.	TAF4 domain-containing protein.	0.929
C3XPP3_BRAFL	C3XU46_BRAFL	C3XPP3	C3XU46	Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family.	TAFH domain-containing protein.	0.929
C3XPP3_BRAFL	C3XWK5_BRAFL	C3XPP3	C3XWK5	Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family.	TAFII55_N domain-containing protein.	0.999
C3XPP3_BRAFL	C3Y0I0_BRAFL	C3XPP3	C3Y0I0	Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family.	Uncharacterized protein.	0.836
C3XPP3_BRAFL	C3Y3A3_BRAFL	C3XPP3	C3Y3A3	Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family.	Uncharacterized protein.	0.999
C3XPP3_BRAFL	C3YBY7_BRAFL	C3XPP3	C3YBY7	Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family.	Uncharacterized protein.	0.808
C3XPP3_BRAFL	C3YEN0_BRAFL	C3XPP3	C3YEN0	Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family.	Uncharacterized protein.	0.929
C3XPP3_BRAFL	C3YEN1_BRAFL	C3XPP3	C3YEN1	Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family.	TAFH domain-containing protein.	0.929
C3XPP3_BRAFL	C3YLI3_BRAFL	C3XPP3	C3YLI3	Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family.	PHD-type domain-containing protein.	0.997
C3XPP3_BRAFL	C3YQI6_BRAFL	C3XPP3	C3YQI6	Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family.	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	0.815
C3XPP3_BRAFL	C3YVD4_BRAFL	C3XPP3	C3YVD4	Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family.	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.	0.810
C3XPP3_BRAFL	C3YW09_BRAFL	C3XPP3	C3YW09	Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family.	TAFII28 domain-containing protein.	0.999
C3XPP3_BRAFL	C3YX15_BRAFL	C3XPP3	C3YX15	Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family.	Peptidase_M1 domain-containing protein.	0.986
C3XPP3_BRAFL	C3YXI9_BRAFL	C3XPP3	C3YXI9	Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family.	Peptidase_M1 domain-containing protein.	0.986
C3XPP3_BRAFL	C3Z2E0_BRAFL	C3XPP3	C3Z2E0	Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family.	HTH TFE/IIEalpha-type domain-containing protein.	0.813
C3XPP3_BRAFL	C3Z4S1_BRAFL	C3XPP3	C3Z4S1	Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family.	TAF domain-containing protein.	0.986