(16 nodes) Heme biosynthetic process network (Branchiostoma floridae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	C3Y5A8_BRAFL	HEM4 domain-containing protein. (205 aa)
	C3XQI2_BRAFL	Uncharacterized protein. (336 aa)
	C3XWC0_BRAFL	Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. (178 aa)
	C3Y5P3_BRAFL	Uncharacterized protein. (301 aa)
	C3Y8V2_BRAFL	Protoheme IX farnesyltransferase, mitochondrial; Converts protoheme IX and farnesyl diphosphate to heme O. Belongs to the ubiA prenyltransferase family. (410 aa)
	C3YQT2_BRAFL	Uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family. (368 aa)
	C3ZAH6_BRAFL	5-aminolevulinate synthase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. (453 aa)
	C3Y1B6_BRAFL	Uncharacterized protein. (102 aa)
	C3ZC55_BRAFL	GCV_T domain-containing protein. (441 aa)
	C3ZC60_BRAFL	Uncharacterized protein. (255 aa)
	C3ZGM5_BRAFL	Uncharacterized protein. (132 aa)
	C3ZJD9_BRAFL	Uncharacterized protein; Belongs to the ferrochelatase family. (402 aa)
	C3ZSM6_BRAFL	Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (475 aa)
	C3ZXJ0_BRAFL	NAD(P)-bd_dom domain-containing protein. (227 aa)
	C3Y1Q5_BRAFL	Porphobil_deam domain-containing protein. (140 aa)
	C3Y301_BRAFL	Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (197 aa)

Your Current Organism:

Branchiostoma floridae

NCBI taxonomy Id: 7739
Other names: Amphioxus floridae, B. floridae, Florida lancelet

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C3XWC0_BRAFL	C3ZJD9_BRAFL	C3XWC0	C3ZJD9	Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family.	Uncharacterized protein; Belongs to the ferrochelatase family.	0.628
C3Y1B6_BRAFL	C3ZJD9_BRAFL	C3Y1B6	C3ZJD9	Uncharacterized protein.	Uncharacterized protein; Belongs to the ferrochelatase family.	0.472
C3Y1B6_BRAFL	C3ZSM6_BRAFL	C3Y1B6	C3ZSM6	Uncharacterized protein.	Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.	0.531
C3Y1Q5_BRAFL	C3Y301_BRAFL	C3Y1Q5	C3Y301	Porphobil_deam domain-containing protein.	Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.	0.997
C3Y1Q5_BRAFL	C3Y5A8_BRAFL	C3Y1Q5	C3Y5A8	Porphobil_deam domain-containing protein.	HEM4 domain-containing protein.	0.996
C3Y1Q5_BRAFL	C3Y5P3_BRAFL	C3Y1Q5	C3Y5P3	Porphobil_deam domain-containing protein.	Uncharacterized protein.	0.705
C3Y1Q5_BRAFL	C3Y8V2_BRAFL	C3Y1Q5	C3Y8V2	Porphobil_deam domain-containing protein.	Protoheme IX farnesyltransferase, mitochondrial; Converts protoheme IX and farnesyl diphosphate to heme O. Belongs to the ubiA prenyltransferase family.	0.719
C3Y1Q5_BRAFL	C3YQT2_BRAFL	C3Y1Q5	C3YQT2	Porphobil_deam domain-containing protein.	Uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family.	0.931
C3Y1Q5_BRAFL	C3ZAH6_BRAFL	C3Y1Q5	C3ZAH6	Porphobil_deam domain-containing protein.	5-aminolevulinate synthase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.	0.722
C3Y1Q5_BRAFL	C3ZJD9_BRAFL	C3Y1Q5	C3ZJD9	Porphobil_deam domain-containing protein.	Uncharacterized protein; Belongs to the ferrochelatase family.	0.851
C3Y1Q5_BRAFL	C3ZSM6_BRAFL	C3Y1Q5	C3ZSM6	Porphobil_deam domain-containing protein.	Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.	0.805
C3Y1Q5_BRAFL	C3ZXJ0_BRAFL	C3Y1Q5	C3ZXJ0	Porphobil_deam domain-containing protein.	NAD(P)-bd_dom domain-containing protein.	0.805
C3Y301_BRAFL	C3Y1Q5_BRAFL	C3Y301	C3Y1Q5	Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.	Porphobil_deam domain-containing protein.	0.997
C3Y301_BRAFL	C3Y5A8_BRAFL	C3Y301	C3Y5A8	Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.	HEM4 domain-containing protein.	0.995
C3Y301_BRAFL	C3Y5P3_BRAFL	C3Y301	C3Y5P3	Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.	Uncharacterized protein.	0.554
C3Y301_BRAFL	C3Y8V2_BRAFL	C3Y301	C3Y8V2	Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.	Protoheme IX farnesyltransferase, mitochondrial; Converts protoheme IX and farnesyl diphosphate to heme O. Belongs to the ubiA prenyltransferase family.	0.706
C3Y301_BRAFL	C3YQT2_BRAFL	C3Y301	C3YQT2	Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.	Uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family.	0.851
C3Y301_BRAFL	C3ZAH6_BRAFL	C3Y301	C3ZAH6	Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.	5-aminolevulinate synthase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.	0.852
C3Y301_BRAFL	C3ZJD9_BRAFL	C3Y301	C3ZJD9	Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.	Uncharacterized protein; Belongs to the ferrochelatase family.	0.797
C3Y301_BRAFL	C3ZSM6_BRAFL	C3Y301	C3ZSM6	Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.	Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.	0.810