(39 nodes) PML body network (Branchiostoma floridae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	C3XVY7_BRAFL	CW-type domain-containing protein. (465 aa)
	C3XWP7_BRAFL	SprT-like domain-containing protein. (658 aa)
	C3XXF8_BRAFL	Uncharacterized protein. (554 aa)
	C3Y1S5_BRAFL	SMC_N domain-containing protein. (1096 aa)
	C3Y2K4_BRAFL	BTB domain-containing protein. (519 aa)
	C3Y3W0_BRAFL	Uncharacterized protein. (678 aa)
	C3Y8N4_BRAFL	Helicase C-terminal domain-containing protein. (591 aa)
	C3YBW9_BRAFL	Small ubiquitin-related modifier. (100 aa)
	C3YDL0_BRAFL	Uncharacterized protein. (638 aa)
	C3YKR1_BRAFL	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (666 aa)
	C3YKX2_BRAFL	Deacetylase sirtuin-type domain-containing protein. (312 aa)
	C3YM09_BRAFL	RING-type domain-containing protein. (262 aa)
	C3YMQ0_BRAFL	SP-RING-type domain-containing protein. (252 aa)
	C3YXN5_BRAFL	Uncharacterized protein. (227 aa)
	C3YZM5_BRAFL	Uncharacterized protein. (453 aa)
	C3YZR1_BRAFL	Uncharacterized protein. (490 aa)
	C3Z1H3_BRAFL	Uncharacterized protein. (270 aa)
	C3Z1H4_BRAFL	Uncharacterized protein. (1738 aa)
	C3Z291_BRAFL	RING-type domain-containing protein. (668 aa)
	C3Z6I4_BRAFL	Uncharacterized protein. (107 aa)
	C3Z741_BRAFL	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (346 aa)
	C3Z742_BRAFL	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (684 aa)
	C3Z8A2_BRAFL	RB_A domain-containing protein. (305 aa)
	C3Z9X0_BRAFL	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2531 aa)
	C3ZBQ9_BRAFL	Helicase ATP-binding domain-containing protein. (270 aa)
	C3ZBT9_BRAFL	Uncharacterized protein. (225 aa)
	C3XT78_BRAFL	Uncharacterized protein. (458 aa)
	C3ZC83_BRAFL	Endo/exonuclease/phosphatase domain-containing protein. (403 aa)
	C3ZFJ3_BRAFL	Uncharacterized protein. (463 aa)
	C3ZHI0_BRAFL	Helicase ATP-binding domain-containing protein. (504 aa)
	C3ZHV8_BRAFL	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (265 aa)
	C3ZIW1_BRAFL	Uncharacterized protein. (174 aa)
	C3ZLL3_BRAFL	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1049 aa)
	C3ZLL7_BRAFL	DUF3385 domain-containing protein. (1400 aa)
	C3ZPA3_BRAFL	Daxx domain-containing protein. (323 aa)
	C3ZPX7_BRAFL	Uncharacterized protein; Belongs to the peptidase C19 family. (1046 aa)
	C3ZR83_BRAFL	Uncharacterized protein. (459 aa)
	C3ZS00_BRAFL	SMC_N domain-containing protein. (1059 aa)
	C3ZV28_BRAFL	Uncharacterized protein. (383 aa)

Your Current Organism:

Branchiostoma floridae

NCBI taxonomy Id: 7739
Other names: Amphioxus floridae, B. floridae, Florida lancelet

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C3XT78_BRAFL	C3Z1H3_BRAFL	C3XT78	C3Z1H3	Uncharacterized protein.	Uncharacterized protein.	0.431
C3XT78_BRAFL	C3Z1H4_BRAFL	C3XT78	C3Z1H4	Uncharacterized protein.	Uncharacterized protein.	0.431
C3XT78_BRAFL	C3Z741_BRAFL	C3XT78	C3Z741	Uncharacterized protein.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.643
C3XT78_BRAFL	C3Z742_BRAFL	C3XT78	C3Z742	Uncharacterized protein.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.643
C3XT78_BRAFL	C3Z9X0_BRAFL	C3XT78	C3Z9X0	Uncharacterized protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.610
C3XT78_BRAFL	C3ZHV8_BRAFL	C3XT78	C3ZHV8	Uncharacterized protein.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.658
C3XT78_BRAFL	C3ZIW1_BRAFL	C3XT78	C3ZIW1	Uncharacterized protein.	Uncharacterized protein.	0.414
C3XXF8_BRAFL	C3Y2K4_BRAFL	C3XXF8	C3Y2K4	Uncharacterized protein.	BTB domain-containing protein.	0.809
C3XXF8_BRAFL	C3ZIW1_BRAFL	C3XXF8	C3ZIW1	Uncharacterized protein.	Uncharacterized protein.	0.503
C3XXF8_BRAFL	C3ZLL3_BRAFL	C3XXF8	C3ZLL3	Uncharacterized protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.516
C3XXF8_BRAFL	C3ZLL7_BRAFL	C3XXF8	C3ZLL7	Uncharacterized protein.	DUF3385 domain-containing protein.	0.516
C3Y1S5_BRAFL	C3YBW9_BRAFL	C3Y1S5	C3YBW9	SMC_N domain-containing protein.	Small ubiquitin-related modifier.	0.855
C3Y1S5_BRAFL	C3YMQ0_BRAFL	C3Y1S5	C3YMQ0	SMC_N domain-containing protein.	SP-RING-type domain-containing protein.	0.999
C3Y1S5_BRAFL	C3YZR1_BRAFL	C3Y1S5	C3YZR1	SMC_N domain-containing protein.	Uncharacterized protein.	0.511
C3Y1S5_BRAFL	C3Z741_BRAFL	C3Y1S5	C3Z741	SMC_N domain-containing protein.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.579
C3Y1S5_BRAFL	C3Z742_BRAFL	C3Y1S5	C3Z742	SMC_N domain-containing protein.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.579
C3Y1S5_BRAFL	C3Z8A2_BRAFL	C3Y1S5	C3Z8A2	SMC_N domain-containing protein.	RB_A domain-containing protein.	0.404
C3Y1S5_BRAFL	C3Z9X0_BRAFL	C3Y1S5	C3Z9X0	SMC_N domain-containing protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.673
C3Y1S5_BRAFL	C3ZS00_BRAFL	C3Y1S5	C3ZS00	SMC_N domain-containing protein.	SMC_N domain-containing protein.	0.999
C3Y1S5_BRAFL	C3ZV28_BRAFL	C3Y1S5	C3ZV28	SMC_N domain-containing protein.	Uncharacterized protein.	0.541