(77 nodes) Negative regulation of translation network (Branchiostoma floridae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	C3ZVZ7_BRAFL	CCHC-type domain-containing protein. (187 aa)
	C3ZVZ9_BRAFL	Uncharacterized protein. (105 aa)
	C3ZYQ0_BRAFL	Endo/exonuclease/phosphatase domain-containing protein. (370 aa)
	C4A039_BRAFL	Signal recognition particle 9 kDa protein; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding. (78 aa)
	C4A0X3_BRAFL	Protein kinase domain-containing protein. (897 aa)
	C3XZ88_BRAFL	Uncharacterized protein. (1596 aa)
	C3XZ12_BRAFL	SAM domain-containing protein. (688 aa)
	C3XYF0_BRAFL	RNB domain-containing protein; Belongs to the RNR ribonuclease family. (813 aa)
	C3XWH9_BRAFL	KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (226 aa)
	PAN3	PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...] (760 aa)
	C3XW58_BRAFL	Uncharacterized protein. (288 aa)
	C3YC97_BRAFL	RNA_bind domain-containing protein. (490 aa)
	C3Y7W6_BRAFL	Uncharacterized protein. (219 aa)
	C3Y6H5_BRAFL	RING-type domain-containing protein. (449 aa)
	C3Y550_BRAFL	Uncharacterized protein. (525 aa)
	C3Y458_BRAFL	DNA_mis_repair domain-containing protein. (717 aa)
	C3Y3S4_BRAFL	Nanos-type domain-containing protein; Belongs to the nanos family. (290 aa)
	C3Y3B0_BRAFL	Endo/exonuclease/phosphatase domain-containing protein. (429 aa)
	C3Y166_BRAFL	S1 motif domain-containing protein. (289 aa)
	C3Y126_BRAFL	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (509 aa)
	C3XZT3_BRAFL	Uncharacterized protein. (347 aa)
	C3XVT6_BRAFL	U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; Belongs to the methyltransferase superfamily. METTL16/RlmF family. (471 aa)
	C3XU47_BRAFL	Uncharacterized protein. (300 aa)
	C3XU17_BRAFL	Uncharacterized protein. (291 aa)
	C3XSQ5_BRAFL	SHMT domain-containing protein. (406 aa)
	C3XZF5_BRAFL	Uncharacterized protein. (427 aa)
	C3YCP5_BRAFL	Uncharacterized protein. (1057 aa)
	C3YEG1_BRAFL	Endo/exonuclease/phosphatase domain-containing protein. (566 aa)
	C3YER5_BRAFL	Uncharacterized protein. (120 aa)
	C3YFD7_BRAFL	Uncharacterized protein; Belongs to the MT-A70-like family. (568 aa)
	C3YFU8_BRAFL	Uncharacterized protein; Belongs to the MT-A70-like family. (164 aa)
	C3YG12_BRAFL	PAT1 domain-containing protein. (1191 aa)
	C3YHH3_BRAFL	Uncharacterized protein. (283 aa)
	C3YIW3_BRAFL	Uncharacterized protein. (356 aa)
	C3YIZ8_BRAFL	Protein kinase domain-containing protein. (1015 aa)
	C3YKW9_BRAFL	Endo/exonuclease/phosphatase domain-containing protein. (554 aa)
	C3YM54_BRAFL	KH_dom_type_1 domain-containing protein. (186 aa)
	C3YN74_BRAFL	Uncharacterized protein. (428 aa)
	C3YQF0_BRAFL	YTH domain-containing protein. (559 aa)
	C3YQT0_BRAFL	C1q domain-containing protein. (220 aa)
	PAN2	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent [...] (1288 aa)
	C3YT44_BRAFL	Uncharacterized protein. (373 aa)
	C3YUB6_BRAFL	TRUD domain-containing protein. (603 aa)
	C3YV22_BRAFL	PCIF1_WW domain-containing protein. (730 aa)
	C3YWD4_BRAFL	Not3 domain-containing protein. (398 aa)
	C3YWD5_BRAFL	NOT2_3_5 domain-containing protein. (286 aa)
	C3YZU4_BRAFL	Uncharacterized protein. (444 aa)
	C3Z0Y4_BRAFL	Protein kinase domain-containing protein. (572 aa)
	C3XRZ6_BRAFL	Uncharacterized protein. (1538 aa)
	C3XPX8_BRAFL	RPOL4c domain-containing protein. (142 aa)
	C3Z2F7_BRAFL	S1 motif domain-containing protein. (723 aa)
	C3Z4Y1_BRAFL	Uncharacterized protein. (272 aa)
	C3Z6B1_BRAFL	Nudix hydrolase domain-containing protein. (596 aa)
	C3Z7Q9_BRAFL	NOT2_3_5 domain-containing protein. (714 aa)
	Hsd11b1H	TRUD domain-containing protein. (274 aa)
	C3Z9T6_BRAFL	Uncharacterized protein. (282 aa)
	C3ZAS4_BRAFL	WW domain-containing protein. (781 aa)
	C3ZB61_BRAFL	Uncharacterized protein. (775 aa)
	C3ZB62_BRAFL	B box-type domain-containing protein. (603 aa)
	C3ZB64_BRAFL	Uncharacterized protein. (136 aa)
	C3ZB66_BRAFL	Uncharacterized protein. (135 aa)
	C3ZB90_BRAFL	Uncharacterized protein. (1629 aa)
	C3ZB91_BRAFL	CNOT1_HEAT domain-containing protein. (918 aa)
	C3ZEH7_BRAFL	Uncharacterized protein. (527 aa)
	C3ZHC7_BRAFL	Uncharacterized protein. (304 aa)
	C3ZIA7_BRAFL	Helicase C-terminal domain-containing protein. (118 aa)
	C3ZJT1_BRAFL	UBA domain-containing protein. (1431 aa)
	C3ZL87_BRAFL	Uncharacterized protein; Belongs to the universal ribosomal protein uL13 family. (204 aa)
	C3ZLB6_BRAFL	Uncharacterized protein. (637 aa)
	C3ZLS8_BRAFL	Uncharacterized protein. (219 aa)
	C3ZN89_BRAFL	Uncharacterized protein. (446 aa)
	C3ZN91_BRAFL	Uncharacterized protein; Belongs to the argonaute family. (812 aa)
	C3ZQ22_BRAFL	Uncharacterized protein; Belongs to the argonaute family. (889 aa)
	C3ZTA6_BRAFL	S1 motif domain-containing protein. (279 aa)
	C3ZTE3_BRAFL	Uncharacterized protein. (1290 aa)
	C3ZTI1_BRAFL	Uncharacterized protein. (487 aa)
	EIF6	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis. (245 aa)

Your Current Organism:

Branchiostoma floridae

NCBI taxonomy Id: 7739
Other names: Amphioxus floridae, B. floridae, Florida lancelet

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C3XPX8_BRAFL	C3YCP5_BRAFL	C3XPX8	C3YCP5	RPOL4c domain-containing protein.	Uncharacterized protein.	0.482
C3XPX8_BRAFL	C3ZJT1_BRAFL	C3XPX8	C3ZJT1	RPOL4c domain-containing protein.	UBA domain-containing protein.	0.594
C3XPX8_BRAFL	C3ZN91_BRAFL	C3XPX8	C3ZN91	RPOL4c domain-containing protein.	Uncharacterized protein; Belongs to the argonaute family.	0.474
C3XPX8_BRAFL	C3ZQ22_BRAFL	C3XPX8	C3ZQ22	RPOL4c domain-containing protein.	Uncharacterized protein; Belongs to the argonaute family.	0.474
C3XRZ6_BRAFL	C3XZ88_BRAFL	C3XRZ6	C3XZ88	Uncharacterized protein.	Uncharacterized protein.	0.865
C3XRZ6_BRAFL	C3Y166_BRAFL	C3XRZ6	C3Y166	Uncharacterized protein.	S1 motif domain-containing protein.	0.897
C3XRZ6_BRAFL	C3YIZ8_BRAFL	C3XRZ6	C3YIZ8	Uncharacterized protein.	Protein kinase domain-containing protein.	0.501
C3XSQ5_BRAFL	C3XZ88_BRAFL	C3XSQ5	C3XZ88	SHMT domain-containing protein.	Uncharacterized protein.	0.900
C3XU17_BRAFL	C3XYF0_BRAFL	C3XU17	C3XYF0	Uncharacterized protein.	RNB domain-containing protein; Belongs to the RNR ribonuclease family.	0.969
C3XU17_BRAFL	C3YC97_BRAFL	C3XU17	C3YC97	Uncharacterized protein.	RNA_bind domain-containing protein.	0.618
C3XU17_BRAFL	C3YM54_BRAFL	C3XU17	C3YM54	Uncharacterized protein.	KH_dom_type_1 domain-containing protein.	0.999
C3XU17_BRAFL	C3YZU4_BRAFL	C3XU17	C3YZU4	Uncharacterized protein.	Uncharacterized protein.	0.999
C3XU17_BRAFL	C3Z6B1_BRAFL	C3XU17	C3Z6B1	Uncharacterized protein.	Nudix hydrolase domain-containing protein.	0.852
C3XU17_BRAFL	C3Z7Q9_BRAFL	C3XU17	C3Z7Q9	Uncharacterized protein.	NOT2_3_5 domain-containing protein.	0.862
C3XU17_BRAFL	C3ZB64_BRAFL	C3XU17	C3ZB64	Uncharacterized protein.	Uncharacterized protein.	0.400
C3XU17_BRAFL	C3ZB66_BRAFL	C3XU17	C3ZB66	Uncharacterized protein.	Uncharacterized protein.	0.400
C3XU17_BRAFL	C3ZLS8_BRAFL	C3XU17	C3ZLS8	Uncharacterized protein.	Uncharacterized protein.	0.999
C3XU17_BRAFL	C3ZTA6_BRAFL	C3XU17	C3ZTA6	Uncharacterized protein.	S1 motif domain-containing protein.	0.999
C3XU47_BRAFL	C3XZ12_BRAFL	C3XU47	C3XZ12	Uncharacterized protein.	SAM domain-containing protein.	0.403
C3XU47_BRAFL	C3XZF5_BRAFL	C3XU47	C3XZF5	Uncharacterized protein.	Uncharacterized protein.	0.997