(26 nodes) Gland morphogenesis network (Branchiostoma floridae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	C3XQC7_BRAFL	POLXc domain-containing protein. (186 aa)
	C3XZP7_BRAFL	Nk homeobox 4. (285 aa)
	C3Y0V7_BRAFL	Fibrinogen C-terminal domain-containing protein. (187 aa)
	C3Y2N6_BRAFL	Uncharacterized protein. (505 aa)
	C3Y3E4_BRAFL	TNFR-Cys domain-containing protein. (948 aa)
	C3YE67_BRAFL	Uncharacterized protein; Belongs to the tumor necrosis factor family. (180 aa)
	C3YGM1_BRAFL	Uncharacterized protein. (127 aa)
	C3YMW6_BRAFL	Uncharacterized protein. (1065 aa)
	C3YQW8_BRAFL	Uncharacterized protein. (536 aa)
	C3YV90_BRAFL	Uncharacterized protein. (786 aa)
	C3YVX7_BRAFL	BTB domain-containing protein. (132 aa)
	C3YW57_BRAFL	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (504 aa)
	C3Z5F6_BRAFL	Fibrinogen C-terminal domain-containing protein. (237 aa)
	C3Z851_BRAFL	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (135 aa)
	C3ZB87_BRAFL	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (138 aa)
	C3ZB88_BRAFL	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (138 aa)
	C3ZDW2_BRAFL	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (374 aa)
	C3ZDW4_BRAFL	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (288 aa)
	C3ZDW5_BRAFL	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (412 aa)
	C3ZDW6_BRAFL	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (412 aa)
	C3ZDY2_BRAFL	CULLIN_2 domain-containing protein; Belongs to the cullin family. (753 aa)
	C3ZHY4_BRAFL	Uncharacterized protein. (502 aa)
	C3ZLL6_BRAFL	Fibrinogen C-terminal domain-containing protein. (1074 aa)
	C3ZZE0_BRAFL	Uncharacterized protein. (669 aa)
	C3ZZQ9_BRAFL	Fibrinogen C-terminal domain-containing protein. (199 aa)
	C4A0W8_BRAFL	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (504 aa)

Your Current Organism:

Branchiostoma floridae

NCBI taxonomy Id: 7739
Other names: Amphioxus floridae, B. floridae, Florida lancelet

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C3Y3E4_BRAFL	C3ZDW2_BRAFL	C3Y3E4	C3ZDW2	TNFR-Cys domain-containing protein.	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	0.818
C3Y3E4_BRAFL	C3ZDW4_BRAFL	C3Y3E4	C3ZDW4	TNFR-Cys domain-containing protein.	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	0.628
C3Y3E4_BRAFL	C3ZDW5_BRAFL	C3Y3E4	C3ZDW5	TNFR-Cys domain-containing protein.	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	0.742
C3Y3E4_BRAFL	C3ZDW6_BRAFL	C3Y3E4	C3ZDW6	TNFR-Cys domain-containing protein.	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	0.818
C3YV90_BRAFL	C3ZZE0_BRAFL	C3YV90	C3ZZE0	Uncharacterized protein.	Uncharacterized protein.	0.913
C3YW57_BRAFL	C4A0W8_BRAFL	C3YW57	C4A0W8	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.543
C3Z851_BRAFL	C3ZB87_BRAFL	C3Z851	C3ZB87	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.904
C3Z851_BRAFL	C3ZB88_BRAFL	C3Z851	C3ZB88	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.904
C3ZB87_BRAFL	C3Z851_BRAFL	C3ZB87	C3Z851	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.904
C3ZB87_BRAFL	C3ZB88_BRAFL	C3ZB87	C3ZB88	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.900
C3ZB88_BRAFL	C3Z851_BRAFL	C3ZB88	C3Z851	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.904
C3ZB88_BRAFL	C3ZB87_BRAFL	C3ZB88	C3ZB87	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.900
C3ZDW2_BRAFL	C3Y3E4_BRAFL	C3ZDW2	C3Y3E4	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	TNFR-Cys domain-containing protein.	0.818
C3ZDW4_BRAFL	C3Y3E4_BRAFL	C3ZDW4	C3Y3E4	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	TNFR-Cys domain-containing protein.	0.628
C3ZDW5_BRAFL	C3Y3E4_BRAFL	C3ZDW5	C3Y3E4	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	TNFR-Cys domain-containing protein.	0.742
C3ZDW6_BRAFL	C3Y3E4_BRAFL	C3ZDW6	C3Y3E4	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	TNFR-Cys domain-containing protein.	0.818
C3ZZE0_BRAFL	C3YV90_BRAFL	C3ZZE0	C3YV90	Uncharacterized protein.	Uncharacterized protein.	0.913
C4A0W8_BRAFL	C3YW57_BRAFL	C4A0W8	C3YW57	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.543