(12 nodes) Intracellular steroid hormone receptor signaling pathway network (Branchiostoma floridae)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	C3ZPA3_BRAFL	Daxx domain-containing protein. (323 aa)
	C3XRB1_BRAFL	Uncharacterized protein. (367 aa)
	C3XTM4_BRAFL	RWD domain-containing protein. (237 aa)
	C3XXN1_BRAFL	HECT domain-containing protein. (1032 aa)
	C3Y201_BRAFL	ASCH domain-containing protein. (608 aa)
	C4A0W8_BRAFL	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (504 aa)
	C3YW27_BRAFL	Uncharacterized protein; Belongs to the DEAD box helicase family. (623 aa)
	C3ZS25_BRAFL	Uncharacterized protein. (2721 aa)
	C3YW57_BRAFL	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (504 aa)
	C3YWS3_BRAFL	Uncharacterized protein; Belongs to the DEAD box helicase family. (709 aa)
	C3Z629_BRAFL	Prohibitin. (276 aa)
	C3ZE20_BRAFL	Uncharacterized protein. (304 aa)

Your Current Organism:

Branchiostoma floridae

NCBI taxonomy Id: 7739
Other names: Amphioxus floridae, B. floridae, Florida lancelet

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C3XRB1_BRAFL	C3XXN1_BRAFL	C3XRB1	C3XXN1	Uncharacterized protein.	HECT domain-containing protein.	0.465
C3XRB1_BRAFL	C3YW27_BRAFL	C3XRB1	C3YW27	Uncharacterized protein.	Uncharacterized protein; Belongs to the DEAD box helicase family.	0.660
C3XRB1_BRAFL	C3YW57_BRAFL	C3XRB1	C3YW57	Uncharacterized protein.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.699
C3XRB1_BRAFL	C3YWS3_BRAFL	C3XRB1	C3YWS3	Uncharacterized protein.	Uncharacterized protein; Belongs to the DEAD box helicase family.	0.660
C3XRB1_BRAFL	C4A0W8_BRAFL	C3XRB1	C4A0W8	Uncharacterized protein.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.699
C3XXN1_BRAFL	C3XRB1_BRAFL	C3XXN1	C3XRB1	HECT domain-containing protein.	Uncharacterized protein.	0.465
C3Y201_BRAFL	C3YW57_BRAFL	C3Y201	C3YW57	ASCH domain-containing protein.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.862
C3Y201_BRAFL	C4A0W8_BRAFL	C3Y201	C4A0W8	ASCH domain-containing protein.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.862
C3YW27_BRAFL	C3XRB1_BRAFL	C3YW27	C3XRB1	Uncharacterized protein; Belongs to the DEAD box helicase family.	Uncharacterized protein.	0.660
C3YW57_BRAFL	C3XRB1_BRAFL	C3YW57	C3XRB1	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Uncharacterized protein.	0.699
C3YW57_BRAFL	C3Y201_BRAFL	C3YW57	C3Y201	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	ASCH domain-containing protein.	0.862
C3YW57_BRAFL	C3ZE20_BRAFL	C3YW57	C3ZE20	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Uncharacterized protein.	0.542
C3YW57_BRAFL	C4A0W8_BRAFL	C3YW57	C4A0W8	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.543
C3YWS3_BRAFL	C3XRB1_BRAFL	C3YWS3	C3XRB1	Uncharacterized protein; Belongs to the DEAD box helicase family.	Uncharacterized protein.	0.660
C3ZE20_BRAFL	C3YW57_BRAFL	C3ZE20	C3YW57	Uncharacterized protein.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.542
C3ZE20_BRAFL	C3ZPA3_BRAFL	C3ZE20	C3ZPA3	Uncharacterized protein.	Daxx domain-containing protein.	0.453
C3ZE20_BRAFL	C4A0W8_BRAFL	C3ZE20	C4A0W8	Uncharacterized protein.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.542
C3ZPA3_BRAFL	C3ZE20_BRAFL	C3ZPA3	C3ZE20	Daxx domain-containing protein.	Uncharacterized protein.	0.453
C4A0W8_BRAFL	C3XRB1_BRAFL	C4A0W8	C3XRB1	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Uncharacterized protein.	0.699
C4A0W8_BRAFL	C3Y201_BRAFL	C4A0W8	C3Y201	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	ASCH domain-containing protein.	0.862