(61 nodes) Intracellular receptor signaling pathway network (Branchiostoma floridae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	C3Z3D9_BRAFL	BHLH domain-containing protein. (233 aa)
	C3Z3E0_BRAFL	BHLH domain-containing protein. (221 aa)
	C3Z507_BRAFL	Nuclear receptor domain-containing protein. (84 aa)
	C3Z508_BRAFL	Uncharacterized protein. (445 aa)
	C3Z629_BRAFL	Prohibitin. (276 aa)
	C3Z6C1_BRAFL	Uncharacterized protein. (369 aa)
	C3Z6H1_BRAFL	Uncharacterized protein. (491 aa)
	C3Z6H2_BRAFL	NR LBD domain-containing protein. (121 aa)
	C3Z6H4_BRAFL	Uncharacterized protein. (320 aa)
	C3Z7Q7_BRAFL	Peptidylprolyl isomerase. (423 aa)
	C3Z7Z3_BRAFL	Uncharacterized protein. (1206 aa)
	C3ZE20_BRAFL	Uncharacterized protein. (304 aa)
	C3ZPA3_BRAFL	Daxx domain-containing protein. (323 aa)
	C3ZPQ2_BRAFL	Uncharacterized protein. (343 aa)
	C3ZPZ7_BRAFL	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (451 aa)
	C3ZQ47_BRAFL	Nuclear receptor domain-containing protein. (70 aa)
	C3ZS25_BRAFL	Uncharacterized protein. (2721 aa)
	C3ZW92_BRAFL	BHLH domain-containing protein. (110 aa)
	C3ZW93_BRAFL	PAS domain-containing protein. (221 aa)
	C3XQI1_BRAFL	Uncharacterized protein. (180 aa)
	C3XQU2_BRAFL	SKIP_SNW domain-containing protein. (543 aa)
	C3XRB0_BRAFL	Uncharacterized protein. (399 aa)
	C3XRB1_BRAFL	Uncharacterized protein. (367 aa)
	C3XRV2_BRAFL	Nuclear receptor domain-containing protein. (81 aa)
	C3XTM4_BRAFL	RWD domain-containing protein. (237 aa)
	C3XU47_BRAFL	Uncharacterized protein. (300 aa)
	C3XUD7_BRAFL	Uncharacterized protein. (486 aa)
	C3XUQ3_BRAFL	Uncharacterized protein. (375 aa)
	C3XUQ6_BRAFL	NR LBD domain-containing protein. (167 aa)
	C3XXN1_BRAFL	HECT domain-containing protein. (1032 aa)
	C3XZR9_BRAFL	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (335 aa)
	C3Y0M6_BRAFL	Uncharacterized protein. (846 aa)
	C3Y201_BRAFL	ASCH domain-containing protein. (608 aa)
	C3Y2V8_BRAFL	Uncharacterized protein. (427 aa)
	C3Y2X1_BRAFL	Uncharacterized protein. (336 aa)
	C3Y717_BRAFL	Nuclear receptor domain-containing protein. (1348 aa)
	C3Y7F3_BRAFL	Protein kinase domain-containing protein. (702 aa)
	C3YEV5_BRAFL	Uncharacterized protein. (359 aa)
	C3YIE7_BRAFL	XPG_I_2 domain-containing protein. (207 aa)
	C3YIU7_BRAFL	Uncharacterized protein. (1125 aa)
	C3YIU8_BRAFL	Uncharacterized protein. (848 aa)
	C3YJ11_BRAFL	Uncharacterized protein. (701 aa)
	C3YPG5_BRAFL	Polyphenol oxidase; Belongs to the multicopper oxidase YfiH/RL5 family. (355 aa)
	C3YPK8_BRAFL	Uncharacterized protein. (1211 aa)
	C3YUP9_BRAFL	Protein kinase domain-containing protein. (925 aa)
	C3YVI8_BRAFL	Uncharacterized protein. (632 aa)
	C3YW27_BRAFL	Uncharacterized protein; Belongs to the DEAD box helicase family. (623 aa)
	C3YW57_BRAFL	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (504 aa)
	C3YWB0_BRAFL	Uncharacterized protein. (672 aa)
	C3YWB1_BRAFL	Uncharacterized protein. (613 aa)
	C3YWB2_BRAFL	Uncharacterized protein. (1279 aa)
	C3YWS3_BRAFL	Uncharacterized protein; Belongs to the DEAD box helicase family. (709 aa)
	C3YYK6_BRAFL	Uncharacterized protein. (581 aa)
	C3YYK7_BRAFL	Uncharacterized protein. (566 aa)
	C3YYX7_BRAFL	Uncharacterized protein. (419 aa)
	C3YZC2_BRAFL	ATPase_AAA_core domain-containing protein. (178 aa)
	C3YZK7_BRAFL	Uncharacterized protein. (608 aa)
	C3Z0Q0_BRAFL	Uncharacterized protein. (526 aa)
	C3ZZ31_BRAFL	Nuclear receptor domain-containing protein. (70 aa)
	C4A0W8_BRAFL	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (504 aa)
	Q8MX80_BRAFL	Retinoic acid receptor. (415 aa)

Your Current Organism:

Branchiostoma floridae

NCBI taxonomy Id: 7739
Other names: Amphioxus floridae, B. floridae, Florida lancelet

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C3XRB0_BRAFL	C3YW57_BRAFL	C3XRB0	C3YW57	Uncharacterized protein.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.541
C3XRB0_BRAFL	C4A0W8_BRAFL	C3XRB0	C4A0W8	Uncharacterized protein.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.541
C3XRB1_BRAFL	C3XXN1_BRAFL	C3XRB1	C3XXN1	Uncharacterized protein.	HECT domain-containing protein.	0.465
C3XRB1_BRAFL	C3YW27_BRAFL	C3XRB1	C3YW27	Uncharacterized protein.	Uncharacterized protein; Belongs to the DEAD box helicase family.	0.660
C3XRB1_BRAFL	C3YW57_BRAFL	C3XRB1	C3YW57	Uncharacterized protein.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.699
C3XRB1_BRAFL	C3YWS3_BRAFL	C3XRB1	C3YWS3	Uncharacterized protein.	Uncharacterized protein; Belongs to the DEAD box helicase family.	0.660
C3XRB1_BRAFL	C3Z508_BRAFL	C3XRB1	C3Z508	Uncharacterized protein.	Uncharacterized protein.	0.548
C3XRB1_BRAFL	C4A0W8_BRAFL	C3XRB1	C4A0W8	Uncharacterized protein.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.699
C3XU47_BRAFL	C3YW27_BRAFL	C3XU47	C3YW27	Uncharacterized protein.	Uncharacterized protein; Belongs to the DEAD box helicase family.	0.420
C3XU47_BRAFL	C3YWS3_BRAFL	C3XU47	C3YWS3	Uncharacterized protein.	Uncharacterized protein; Belongs to the DEAD box helicase family.	0.420
C3XUD7_BRAFL	C3YW57_BRAFL	C3XUD7	C3YW57	Uncharacterized protein.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.569
C3XUD7_BRAFL	C4A0W8_BRAFL	C3XUD7	C4A0W8	Uncharacterized protein.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.569
C3XUQ3_BRAFL	C3YW57_BRAFL	C3XUQ3	C3YW57	Uncharacterized protein.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.441
C3XUQ3_BRAFL	C4A0W8_BRAFL	C3XUQ3	C4A0W8	Uncharacterized protein.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.441
C3XUQ6_BRAFL	C3YW57_BRAFL	C3XUQ6	C3YW57	NR LBD domain-containing protein.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.441
C3XUQ6_BRAFL	C4A0W8_BRAFL	C3XUQ6	C4A0W8	NR LBD domain-containing protein.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.441
C3XXN1_BRAFL	C3XRB1_BRAFL	C3XXN1	C3XRB1	HECT domain-containing protein.	Uncharacterized protein.	0.465
C3Y201_BRAFL	C3YW57_BRAFL	C3Y201	C3YW57	ASCH domain-containing protein.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.862
C3Y201_BRAFL	C4A0W8_BRAFL	C3Y201	C4A0W8	ASCH domain-containing protein.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.862
C3Y2V8_BRAFL	C3YEV5_BRAFL	C3Y2V8	C3YEV5	Uncharacterized protein.	Uncharacterized protein.	0.574