(8 nodes) HOPS complex network (Branchiostoma floridae)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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co-expression

protein homology

Your Input:
	C3XVT2_BRAFL	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (575 aa)
	C3XXM3_BRAFL	Pep3_Vps18 domain-containing protein. (986 aa)
	C3Y4D1_BRAFL	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family. (804 aa)
	C3YEV2_BRAFL	Uncharacterized protein. (288 aa)
	C3YKV1_BRAFL	RING-type domain-containing protein. (894 aa)
	C3YXH4_BRAFL	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family. (761 aa)
	C3Z6B6_BRAFL	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (387 aa)
	C3ZIW0_BRAFL	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family. (795 aa)

Your Current Organism:

Branchiostoma floridae

NCBI taxonomy Id: 7739
Other names: Amphioxus floridae, B. floridae, Florida lancelet

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C3XVT2_BRAFL	C3XXM3_BRAFL	C3XVT2	C3XXM3	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.	Pep3_Vps18 domain-containing protein.	0.981
C3XVT2_BRAFL	C3Y4D1_BRAFL	C3XVT2	C3Y4D1	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.	0.942
C3XVT2_BRAFL	C3YEV2_BRAFL	C3XVT2	C3YEV2	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.	Uncharacterized protein.	0.626
C3XVT2_BRAFL	C3YKV1_BRAFL	C3XVT2	C3YKV1	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.	RING-type domain-containing protein.	0.974
C3XVT2_BRAFL	C3YXH4_BRAFL	C3XVT2	C3YXH4	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	0.976
C3XVT2_BRAFL	C3Z6B6_BRAFL	C3XVT2	C3Z6B6	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.	0.765
C3XVT2_BRAFL	C3ZIW0_BRAFL	C3XVT2	C3ZIW0	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	0.976
C3XXM3_BRAFL	C3XVT2_BRAFL	C3XXM3	C3XVT2	Pep3_Vps18 domain-containing protein.	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.	0.981
C3XXM3_BRAFL	C3Y4D1_BRAFL	C3XXM3	C3Y4D1	Pep3_Vps18 domain-containing protein.	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.	0.998
C3XXM3_BRAFL	C3YEV2_BRAFL	C3XXM3	C3YEV2	Pep3_Vps18 domain-containing protein.	Uncharacterized protein.	0.875
C3XXM3_BRAFL	C3YKV1_BRAFL	C3XXM3	C3YKV1	Pep3_Vps18 domain-containing protein.	RING-type domain-containing protein.	0.998
C3XXM3_BRAFL	C3YXH4_BRAFL	C3XXM3	C3YXH4	Pep3_Vps18 domain-containing protein.	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	0.977
C3XXM3_BRAFL	C3Z6B6_BRAFL	C3XXM3	C3Z6B6	Pep3_Vps18 domain-containing protein.	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.	0.949
C3XXM3_BRAFL	C3ZIW0_BRAFL	C3XXM3	C3ZIW0	Pep3_Vps18 domain-containing protein.	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	0.977
C3Y4D1_BRAFL	C3XVT2_BRAFL	C3Y4D1	C3XVT2	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.	0.942
C3Y4D1_BRAFL	C3XXM3_BRAFL	C3Y4D1	C3XXM3	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.	Pep3_Vps18 domain-containing protein.	0.998
C3Y4D1_BRAFL	C3YEV2_BRAFL	C3Y4D1	C3YEV2	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.	Uncharacterized protein.	0.952
C3Y4D1_BRAFL	C3YKV1_BRAFL	C3Y4D1	C3YKV1	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.	RING-type domain-containing protein.	0.998
C3Y4D1_BRAFL	C3YXH4_BRAFL	C3Y4D1	C3YXH4	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	0.975
C3Y4D1_BRAFL	C3Z6B6_BRAFL	C3Y4D1	C3Z6B6	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.	0.942