(52 nodes) Site of double-strand break network (Branchiostoma floridae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	C3Z273_BRAFL	SMC hinge domain-containing protein. (1148 aa)
	C3XXK2_BRAFL	Uncharacterized protein. (212 aa)
	C3Y212_BRAFL	Deacetylase sirtuin-type domain-containing protein. (414 aa)
	C3Y429_BRAFL	Uncharacterized protein. (1173 aa)
	C3Y4G6_BRAFL	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (293 aa)
	C3Y4R4_BRAFL	Helicase C-terminal domain-containing protein. (392 aa)
	C3Y4U9_BRAFL	Uncharacterized protein. (120 aa)
	C3Y6Y9_BRAFL	Uncharacterized protein. (861 aa)
	C3Y6Z8_BRAFL	Uncharacterized protein. (972 aa)
	C3Y7Z7_BRAFL	Checkpoint protein; Belongs to the HUS1 family. (280 aa)
	C3Y909_BRAFL	Deacetylase sirtuin-type domain-containing protein. (399 aa)
	C3YBF4_BRAFL	Uncharacterized protein. (2359 aa)
	C3YDF6_BRAFL	ANK_REP_REGION domain-containing protein. (91 aa)
	C3YDS9_BRAFL	Uncharacterized protein. (326 aa)
	C3YFK4_BRAFL	Uncharacterized protein. (683 aa)
	C3YG90_BRAFL	FHA_2 domain-containing protein. (633 aa)
	C3YGG0_BRAFL	Uncharacterized protein. (1356 aa)
	C3YJ28_BRAFL	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (510 aa)
	C3YLR5_BRAFL	Uncharacterized protein. (451 aa)
	C3YMU6_BRAFL	Death domain-containing protein. (482 aa)
	C3YPV2_BRAFL	Uncharacterized protein. (170 aa)
	C3YT49_BRAFL	Uncharacterized protein. (471 aa)
	C3YT95_BRAFL	Uncharacterized protein. (1560 aa)
	C3YTH4_BRAFL	Uncharacterized protein; Belongs to the AAA ATPase family. (718 aa)
	C3YUN6_BRAFL	Uncharacterized protein. (118 aa)
	C3YV86_BRAFL	Uncharacterized protein. (269 aa)
	C3YVM0_BRAFL	SAP domain-containing protein. (299 aa)
	C3YVN0_BRAFL	Uncharacterized protein. (511 aa)
	C3YWA5_BRAFL	AAA_23 domain-containing protein. (187 aa)
	C3YXK5_BRAFL	UvrD_C_2 domain-containing protein. (1283 aa)
	C3Z054_BRAFL	Uncharacterized protein. (858 aa)
	C3Z057_BRAFL	TIMELESS domain-containing protein. (201 aa)
	C3Z272_BRAFL	Uncharacterized protein. (725 aa)
	C3Z2P3_BRAFL	Poly [ADP-ribose] polymerase. (516 aa)
	C3Z3L2_BRAFL	UmuC domain-containing protein. (354 aa)
	C3Z655_BRAFL	Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (159 aa)
	C3Z6D3_BRAFL	Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (181 aa)
	C3ZBE1_BRAFL	Uncharacterized protein. (344 aa)
	C3ZCS1_BRAFL	Uncharacterized protein. (716 aa)
	C3ZEN4_BRAFL	Mre11_DNA_bind domain-containing protein. (441 aa)
	C3ZET1_BRAFL	Uncharacterized protein. (632 aa)
	C3ZET3_BRAFL	RING-type domain-containing protein. (121 aa)
	C3ZF60_BRAFL	WD_REPEATS_REGION domain-containing protein. (434 aa)
	C3ZMJ6_BRAFL	CPSF_A domain-containing protein. (1152 aa)
	C3ZMX5_BRAFL	Uncharacterized protein. (1057 aa)
	C3ZNR8_BRAFL	Uncharacterized protein. (987 aa)
	C3ZS00_BRAFL	SMC_N domain-containing protein. (1059 aa)
	C3ZS16_BRAFL	SMC hinge domain-containing protein. (1932 aa)
	C3ZTJ4_BRAFL	Uncharacterized protein. (502 aa)
	C3ZZE8_BRAFL	Uncharacterized protein; Belongs to the actin family. (418 aa)
	C3ZZJ5_BRAFL	FHA_2 domain-containing protein. (427 aa)
	C4A0H4_BRAFL	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (394 aa)

Your Current Organism:

Branchiostoma floridae

NCBI taxonomy Id: 7739
Other names: Amphioxus floridae, B. floridae, Florida lancelet

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C3XXK2_BRAFL	C3YDS9_BRAFL	C3XXK2	C3YDS9	Uncharacterized protein.	Uncharacterized protein.	0.765
C3XXK2_BRAFL	C3ZZJ5_BRAFL	C3XXK2	C3ZZJ5	Uncharacterized protein.	FHA_2 domain-containing protein.	0.439
C3Y212_BRAFL	C3ZMX5_BRAFL	C3Y212	C3ZMX5	Deacetylase sirtuin-type domain-containing protein.	Uncharacterized protein.	0.800
C3Y4G6_BRAFL	C3YPV2_BRAFL	C3Y4G6	C3YPV2	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	Uncharacterized protein.	0.999
C3Y4G6_BRAFL	C3Z655_BRAFL	C3Y4G6	C3Z655	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	0.998
C3Y4G6_BRAFL	C3Z6D3_BRAFL	C3Y4G6	C3Z6D3	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	0.992
C3Y4G6_BRAFL	C3ZZE8_BRAFL	C3Y4G6	C3ZZE8	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	Uncharacterized protein; Belongs to the actin family.	0.999
C3Y4G6_BRAFL	C4A0H4_BRAFL	C3Y4G6	C4A0H4	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	0.999
C3Y4R4_BRAFL	C3Y7Z7_BRAFL	C3Y4R4	C3Y7Z7	Helicase C-terminal domain-containing protein.	Checkpoint protein; Belongs to the HUS1 family.	0.422
C3Y4R4_BRAFL	C3YBF4_BRAFL	C3Y4R4	C3YBF4	Helicase C-terminal domain-containing protein.	Uncharacterized protein.	0.436
C3Y4R4_BRAFL	C3YDF6_BRAFL	C3Y4R4	C3YDF6	Helicase C-terminal domain-containing protein.	ANK_REP_REGION domain-containing protein.	0.435
C3Y4R4_BRAFL	C3YUN6_BRAFL	C3Y4R4	C3YUN6	Helicase C-terminal domain-containing protein.	Uncharacterized protein.	0.489
C3Y4R4_BRAFL	C3YWA5_BRAFL	C3Y4R4	C3YWA5	Helicase C-terminal domain-containing protein.	AAA_23 domain-containing protein.	0.547
C3Y4R4_BRAFL	C3ZEN4_BRAFL	C3Y4R4	C3ZEN4	Helicase C-terminal domain-containing protein.	Mre11_DNA_bind domain-containing protein.	0.603
C3Y4R4_BRAFL	C3ZMX5_BRAFL	C3Y4R4	C3ZMX5	Helicase C-terminal domain-containing protein.	Uncharacterized protein.	0.420
C3Y4U9_BRAFL	C3Y6Y9_BRAFL	C3Y4U9	C3Y6Y9	Uncharacterized protein.	Uncharacterized protein.	0.937
C3Y4U9_BRAFL	C3Y6Z8_BRAFL	C3Y4U9	C3Y6Z8	Uncharacterized protein.	Uncharacterized protein.	0.937
C3Y6Y9_BRAFL	C3Y4U9_BRAFL	C3Y6Y9	C3Y4U9	Uncharacterized protein.	Uncharacterized protein.	0.937
C3Y6Z8_BRAFL	C3Y4U9_BRAFL	C3Y6Z8	C3Y4U9	Uncharacterized protein.	Uncharacterized protein.	0.937
C3Y7Z7_BRAFL	C3Y4R4_BRAFL	C3Y7Z7	C3Y4R4	Checkpoint protein; Belongs to the HUS1 family.	Helicase C-terminal domain-containing protein.	0.422