(37 nodes) Pteridine-containing compound metabolic process network (Branchiostoma floridae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	C3XPE4_BRAFL	Uncharacterized protein. (259 aa)
	C3XPI2_BRAFL	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (686 aa)
	C3XQB2_BRAFL	Uncharacterized protein. (291 aa)
	C3XQW7_BRAFL	Uncharacterized protein. (249 aa)
	C3XQX1_BRAFL	Uncharacterized protein. (269 aa)
	C3XSJ5_BRAFL	Uncharacterized protein. (699 aa)
	C3XSQ5_BRAFL	SHMT domain-containing protein. (406 aa)
	C3XWV6_BRAFL	FolB domain-containing protein. (298 aa)
	C3XZ05_BRAFL	GTP_cyclohydroI domain-containing protein. (180 aa)
	C3Y0Q9_BRAFL	Uncharacterized protein. (264 aa)
	C3Y126_BRAFL	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (509 aa)
	C3Y298_BRAFL	Uncharacterized protein. (1033 aa)
	C3Y3M8_BRAFL	Uncharacterized protein. (269 aa)
	C3YH00_BRAFL	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1318 aa)
	C3YSY8_BRAFL	FolB domain-containing protein. (1284 aa)
	C3YVK9_BRAFL	FolB domain-containing protein. (311 aa)
	C3YVL1_BRAFL	GTP_cyclohydroI domain-containing protein. (180 aa)
	C3Z0P2_BRAFL	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (185 aa)
	C3Z3N4_BRAFL	Uncharacterized protein. (934 aa)
	C3Z5D4_BRAFL	Uncharacterized protein. (97 aa)
	C3Z745_BRAFL	Uncharacterized protein. (252 aa)
	C3Z746_BRAFL	Folate gamma-glutamyl hydrolase. (317 aa)
	C3Z747_BRAFL	Folate gamma-glutamyl hydrolase. (298 aa)
	C3Z748_BRAFL	Folate gamma-glutamyl hydrolase. (318 aa)
	C3Z7V0_BRAFL	DUF4515 domain-containing protein. (310 aa)
	C3Z8L4_BRAFL	Uncharacterized protein. (541 aa)
	C3Z9Z6_BRAFL	Uncharacterized protein. (271 aa)
	C3ZBP8_BRAFL	Uncharacterized protein. (150 aa)
	C3ZFJ1_BRAFL	Uncharacterized protein. (628 aa)
	C3ZFK0_BRAFL	Uncharacterized protein. (629 aa)
	C3ZNF8_BRAFL	RibD_C domain-containing protein. (186 aa)
	C3ZPE3_BRAFL	Uncharacterized protein. (569 aa)
	C3ZPF0_BRAFL	Uncharacterized protein. (672 aa)
	C3ZR25_BRAFL	Uncharacterized protein. (272 aa)
	C3ZVI5_BRAFL	Carrier domain-containing protein; Belongs to the aldehyde dehydrogenase family. (936 aa)
	C3ZVK0_BRAFL	10-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. (909 aa)
	C3ZZU2_BRAFL	THF_DHG_CYH_C domain-containing protein. (755 aa)

Your Current Organism:

Branchiostoma floridae

NCBI taxonomy Id: 7739
Other names: Amphioxus floridae, B. floridae, Florida lancelet

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C3XPE4_BRAFL	C3XQX1_BRAFL	C3XPE4	C3XQX1	Uncharacterized protein.	Uncharacterized protein.	0.904
C3XPE4_BRAFL	C3Y0Q9_BRAFL	C3XPE4	C3Y0Q9	Uncharacterized protein.	Uncharacterized protein.	0.904
C3XPE4_BRAFL	C3Y3M8_BRAFL	C3XPE4	C3Y3M8	Uncharacterized protein.	Uncharacterized protein.	0.905
C3XPE4_BRAFL	C3Z0P2_BRAFL	C3XPE4	C3Z0P2	Uncharacterized protein.	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	0.921
C3XPE4_BRAFL	C3Z9Z6_BRAFL	C3XPE4	C3Z9Z6	Uncharacterized protein.	Uncharacterized protein.	0.904
C3XPE4_BRAFL	C3ZBP8_BRAFL	C3XPE4	C3ZBP8	Uncharacterized protein.	Uncharacterized protein.	0.953
C3XPI2_BRAFL	C3XQB2_BRAFL	C3XPI2	C3XQB2	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	Uncharacterized protein.	0.996
C3XPI2_BRAFL	C3XSJ5_BRAFL	C3XPI2	C3XSJ5	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	Uncharacterized protein.	0.737
C3XPI2_BRAFL	C3XSQ5_BRAFL	C3XPI2	C3XSQ5	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	SHMT domain-containing protein.	0.949
C3XPI2_BRAFL	C3XWV6_BRAFL	C3XPI2	C3XWV6	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	FolB domain-containing protein.	0.445
C3XPI2_BRAFL	C3XZ05_BRAFL	C3XPI2	C3XZ05	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	GTP_cyclohydroI domain-containing protein.	0.516
C3XPI2_BRAFL	C3Y126_BRAFL	C3XPI2	C3Y126	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.994
C3XPI2_BRAFL	C3Y298_BRAFL	C3XPI2	C3Y298	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	Uncharacterized protein.	0.574
C3XPI2_BRAFL	C3YH00_BRAFL	C3XPI2	C3YH00	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.870
C3XPI2_BRAFL	C3YSY8_BRAFL	C3XPI2	C3YSY8	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	FolB domain-containing protein.	0.445
C3XPI2_BRAFL	C3YVK9_BRAFL	C3XPI2	C3YVK9	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	FolB domain-containing protein.	0.445
C3XPI2_BRAFL	C3YVL1_BRAFL	C3XPI2	C3YVL1	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	GTP_cyclohydroI domain-containing protein.	0.516
C3XPI2_BRAFL	C3Z0P2_BRAFL	C3XPI2	C3Z0P2	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	0.710
C3XPI2_BRAFL	C3Z3N4_BRAFL	C3XPI2	C3Z3N4	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	Uncharacterized protein.	0.972
C3XPI2_BRAFL	C3Z8L4_BRAFL	C3XPI2	C3Z8L4	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	Uncharacterized protein.	0.754