(75 nodes) Regulation of cysteine-type endopeptidase activity involved in apoptotic process network (Branchiostoma floridae)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	C3XPS9_BRAFL	Uncharacterized protein; Belongs to the peptidase C14A family. (309 aa)
	C3XQ28_BRAFL	RING-type domain-containing protein. (545 aa)
	C3XQL8_BRAFL	Uncharacterized protein. (318 aa)
	C3XQY8_BRAFL	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (189 aa)
	C3XRN1_BRAFL	Uncharacterized protein. (1244 aa)
	C3XVA5_BRAFL	Uncharacterized protein. (1268 aa)
	C3XVR2_BRAFL	WD_REPEATS_REGION domain-containing protein. (353 aa)
	C3XVR3_BRAFL	WD_REPEATS_REGION domain-containing protein. (187 aa)
	C3XVS3_BRAFL	WD_REPEATS_REGION domain-containing protein. (200 aa)
	C3XVS4_BRAFL	WD_REPEATS_REGION domain-containing protein. (187 aa)
	C3XWH9_BRAFL	KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (226 aa)
	C3XWL4_BRAFL	BHLH domain-containing protein. (342 aa)
	C3XXK4_BRAFL	Uncharacterized protein. (414 aa)
	C3Y1U1_BRAFL	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (268 aa)
	C3Y235_BRAFL	BHLH domain-containing protein. (369 aa)
	C3Y396_BRAFL	Uncharacterized protein; Belongs to the peptidase C14A family. (242 aa)
	Avp	Vasopressin-neurophysin protein. (167 aa)
	C3Y6U5_BRAFL	Uncharacterized protein. (360 aa)
	C3Y726_BRAFL	Uncharacterized protein. (215 aa)
	C3Y7M2_BRAFL	Uncharacterized protein; Belongs to the peptidase C19 family. (1318 aa)
	C3YAZ4_BRAFL	CARD domain-containing protein. (324 aa)
	C3YBE6_BRAFL	Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (246 aa)
	C3YCD8_BRAFL	Uncharacterized protein. (375 aa)
	C3YDJ4_BRAFL	RING-type domain-containing protein. (299 aa)
	C3YE70_BRAFL	Death domain-containing protein. (89 aa)
	C3YEQ1_BRAFL	Uncharacterized protein; Belongs to the peptidase C14A family. (476 aa)
	C3YEW7_BRAFL	Uncharacterized protein. (460 aa)
	C3YGK1_BRAFL	Uncharacterized protein. (410 aa)
	C3YGU4_BRAFL	MYND-type domain-containing protein. (312 aa)
	C3YHW8_BRAFL	FAD-binding PCMH-type domain-containing protein. (419 aa)
	C3YHY5_BRAFL	FAD-binding PCMH-type domain-containing protein. (379 aa)
	C3YIR6_BRAFL	Uncharacterized protein. (113 aa)
	C3YIZ8_BRAFL	Protein kinase domain-containing protein. (1015 aa)
	C3YJ81_BRAFL	Uncharacterized protein. (645 aa)
	C3YKX2_BRAFL	Deacetylase sirtuin-type domain-containing protein. (312 aa)
	C3YKX9_BRAFL	Uncharacterized protein. (564 aa)
	C3YM60_BRAFL	Uncharacterized protein; Belongs to the peptidase C14A family. (540 aa)
	C3YPG2_BRAFL	Uncharacterized protein. (188 aa)
	C3YSZ9_BRAFL	FAD-binding PCMH-type domain-containing protein. (517 aa)
	C3YTI2_BRAFL	FAD-binding PCMH-type domain-containing protein. (517 aa)
	C3YW92_BRAFL	DNA_binding_1 domain-containing protein. (166 aa)
	C3YWJ6_BRAFL	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (96 aa)
	C3YWW3_BRAFL	Uncharacterized protein. (2425 aa)
	C3YYL2_BRAFL	Uncharacterized protein. (106 aa)
	C3YZ38_BRAFL	Uncharacterized protein; Belongs to the peptidase C14A family. (809 aa)
	C3YZW2_BRAFL	Uncharacterized protein. (485 aa)
	C3Z1L4_BRAFL	NACHT domain-containing protein. (1135 aa)
	C3Z2N3_BRAFL	Uncharacterized protein. (621 aa)
	C3Z427_BRAFL	FYVE-type domain-containing protein. (325 aa)
	C3Z5N3_BRAFL	RING-type domain-containing protein. (358 aa)
	C3Z5V2_BRAFL	RING-type domain-containing protein. (395 aa)
	C3Z5V3_BRAFL	RING-type domain-containing protein. (376 aa)
	C3Z5V4_BRAFL	RING-type domain-containing protein. (371 aa)
	C3Z5X5_BRAFL	UDENN FNIP1/2-type domain-containing protein. (1126 aa)
	C3Z8U0_BRAFL	Uncharacterized protein. (572 aa)
	C3Z946_BRAFL	Uncharacterized protein. (310 aa)
	C3Z9S3_BRAFL	RING-type domain-containing protein. (370 aa)
	C3ZDH2_BRAFL	RING-type domain-containing protein. (426 aa)
	C3ZDH3_BRAFL	RING-type domain-containing protein. (861 aa)
	C3ZJQ8_BRAFL	RING-type domain-containing protein. (267 aa)
	C3ZJT9_BRAFL	Uncharacterized protein. (109 aa)
	C3ZNI8_BRAFL	Uncharacterized protein. (297 aa)
	C3ZQ20_BRAFL	Uncharacterized protein. (62 aa)
	C3ZQ72_BRAFL	Uncharacterized protein. (173 aa)
	C3ZQQ4_BRAFL	Uncharacterized protein. (197 aa)
	C3ZQU2_BRAFL	Uncharacterized protein; Belongs to the peptidase C14A family. (739 aa)
	C3ZRU7_BRAFL	Uncharacterized protein. (120 aa)
	C3ZWQ3_BRAFL	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (125 aa)
	C3ZWS9_BRAFL	EGF-like domain-containing protein. (710 aa)
	C3ZXH2_BRAFL	Uncharacterized protein; Belongs to the peptidase C14A family. (340 aa)
	C3ZXH5_BRAFL	Uncharacterized protein; Belongs to the peptidase C14A family. (439 aa)
	C3ZXK9_BRAFL	Uncharacterized protein. (246 aa)
	C3ZXL0_BRAFL	Protein kinase domain-containing protein. (96 aa)
	C3ZY21_BRAFL	Uncharacterized protein; Belongs to the peptidase C14A family. (246 aa)
	C3ZY28_BRAFL	CARD domain-containing protein. (105 aa)

Your Current Organism:

Branchiostoma floridae

NCBI taxonomy Id: 7739
Other names: Amphioxus floridae, B. floridae, Florida lancelet

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C3XPS9_BRAFL	C3YJ81_BRAFL	C3XPS9	C3YJ81	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein.	0.541
C3XPS9_BRAFL	C3YPG2_BRAFL	C3XPS9	C3YPG2	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein.	0.504
C3XPS9_BRAFL	C3ZQQ4_BRAFL	C3XPS9	C3ZQQ4	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein.	0.504
C3XQ28_BRAFL	C3Y726_BRAFL	C3XQ28	C3Y726	RING-type domain-containing protein.	Uncharacterized protein.	0.630
C3XQ28_BRAFL	C3Z5V2_BRAFL	C3XQ28	C3Z5V2	RING-type domain-containing protein.	RING-type domain-containing protein.	0.900
C3XQY8_BRAFL	C3YIR6_BRAFL	C3XQY8	C3YIR6	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	Uncharacterized protein.	0.795
C3XQY8_BRAFL	C3ZWQ3_BRAFL	C3XQY8	C3ZWQ3	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	0.900
C3XVR2_BRAFL	C3XVR3_BRAFL	C3XVR2	C3XVR3	WD_REPEATS_REGION domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.915
C3XVR2_BRAFL	C3XVS4_BRAFL	C3XVR2	C3XVS4	WD_REPEATS_REGION domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.915
C3XVR3_BRAFL	C3XVR2_BRAFL	C3XVR3	C3XVR2	WD_REPEATS_REGION domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.915
C3XVR3_BRAFL	C3XVS3_BRAFL	C3XVR3	C3XVS3	WD_REPEATS_REGION domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.915
C3XVS3_BRAFL	C3XVR3_BRAFL	C3XVS3	C3XVR3	WD_REPEATS_REGION domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.915
C3XVS3_BRAFL	C3XVS4_BRAFL	C3XVS3	C3XVS4	WD_REPEATS_REGION domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.916
C3XVS4_BRAFL	C3XVR2_BRAFL	C3XVS4	C3XVR2	WD_REPEATS_REGION domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.915
C3XVS4_BRAFL	C3XVS3_BRAFL	C3XVS4	C3XVS3	WD_REPEATS_REGION domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.916
C3XWH9_BRAFL	C3ZRU7_BRAFL	C3XWH9	C3ZRU7	KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family.	Uncharacterized protein.	0.859
C3Y396_BRAFL	C3Y726_BRAFL	C3Y396	C3Y726	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein.	0.486
C3Y396_BRAFL	C3Z5N3_BRAFL	C3Y396	C3Z5N3	Uncharacterized protein; Belongs to the peptidase C14A family.	RING-type domain-containing protein.	0.425
C3Y396_BRAFL	C3Z5V2_BRAFL	C3Y396	C3Z5V2	Uncharacterized protein; Belongs to the peptidase C14A family.	RING-type domain-containing protein.	0.425
C3Y396_BRAFL	C3Z5V3_BRAFL	C3Y396	C3Z5V3	Uncharacterized protein; Belongs to the peptidase C14A family.	RING-type domain-containing protein.	0.425