(76 nodes) Dicarboxylic acid metabolic process network (Branchiostoma floridae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	C3XQA6_BRAFL	Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (507 aa)
	KYNU	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (467 aa)
	C3ZBV1_BRAFL	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (328 aa)
	C3ZBR3_BRAFL	Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. (436 aa)
	C3ZBB6_BRAFL	Uncharacterized protein. (566 aa)
	C3ZAU8_BRAFL	Uncharacterized protein. (623 aa)
	C3Z9N1_BRAFL	CN hydrolase domain-containing protein. (279 aa)
	C3Z929_BRAFL	Histidine ammonia-lyase; Belongs to the PAL/histidase family. (648 aa)
	C3Z927_BRAFL	Amidohydro-rel domain-containing protein. (431 aa)
	C3Z8L4_BRAFL	Uncharacterized protein. (541 aa)
	C3Z4P9_BRAFL	Transket_pyr domain-containing protein. (1033 aa)
	C3Z4H8_BRAFL	Uncharacterized protein. (704 aa)
	C3Z482_BRAFL	Malate dehydrogenase. (340 aa)
	C3Z3N4_BRAFL	Uncharacterized protein. (934 aa)
	C3YZQ9_BRAFL	Aldo_ket_red domain-containing protein. (285 aa)
	C3YZI1_BRAFL	Aminotran_1_2 domain-containing protein. (214 aa)
	C3YYZ1_BRAFL	N-acetyltransferase domain-containing protein. (726 aa)
	C3YVK9_BRAFL	FolB domain-containing protein. (311 aa)
	C3YSY8_BRAFL	FolB domain-containing protein. (1284 aa)
	C3YSJ9_BRAFL	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (411 aa)
	C3YRL8_BRAFL	Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. (536 aa)
	C3YQ59_BRAFL	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (459 aa)
	C3YNY7_BRAFL	ATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family. (1097 aa)
	C3YN21_BRAFL	FAD-binding PCMH-type domain-containing protein. (534 aa)
	C3YMM1_BRAFL	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (668 aa)
	C3YKQ6_BRAFL	Fe-ADH domain-containing protein. (423 aa)
	C3YKB5_BRAFL	4Fe-4S ferredoxin-type domain-containing protein. (601 aa)
	C3YJ38_BRAFL	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (416 aa)
	C3YJ03_BRAFL	Uncharacterized protein. (1027 aa)
	C3YIV5_BRAFL	Aminotran_1_2 domain-containing protein. (412 aa)
	C3YGV7_BRAFL	FAD_binding_3 domain-containing protein. (318 aa)
	C3YD19_BRAFL	Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. (310 aa)
	C3YAZ0_BRAFL	ELFV_dehydrog domain-containing protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (795 aa)
	C3YA28_BRAFL	Uncharacterized protein. (156 aa)
	C3Y363_BRAFL	DUF4392 domain-containing protein. (592 aa)
	C3Y126_BRAFL	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (509 aa)
	C3Y093_BRAFL	Uncharacterized protein. (259 aa)
	C3Y076_BRAFL	Uncharacterized protein. (467 aa)
	C3XWV6_BRAFL	FolB domain-containing protein. (298 aa)
	C3XWI3_BRAFL	Aminotran_1_2 domain-containing protein. (195 aa)
	C3XV18_BRAFL	Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (556 aa)
	C3XV17_BRAFL	Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (488 aa)
	C3XUM8_BRAFL	Glutamine amidotransferase type-2 domain-containing protein. (2071 aa)
	C3XU11_BRAFL	DUF4392 domain-containing protein. (615 aa)
	C3XSQ5_BRAFL	SHMT domain-containing protein. (406 aa)
	C3XSJ5_BRAFL	Uncharacterized protein. (699 aa)
	C3XSF7_BRAFL	Glutaredoxin domain-containing protein. (522 aa)
	C3XQB1_BRAFL	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (326 aa)
	C3XQA7_BRAFL	ELFV_dehydrog_N domain-containing protein. (107 aa)
	C3XPB8_BRAFL	Uncharacterized protein. (570 aa)
	C4A0S7_BRAFL	Aldedh domain-containing protein. (339 aa)
	C3ZZU2_BRAFL	THF_DHG_CYH_C domain-containing protein. (755 aa)
	C3ZZM5_BRAFL	Uncharacterized protein. (407 aa)
	C3ZZM4_BRAFL	Transket_pyr domain-containing protein. (303 aa)
	C3ZZL9_BRAFL	Aspartate aminotransferase. (387 aa)
	C3ZY87_BRAFL	2-Hacid_dh_C domain-containing protein. (195 aa)
	C3ZXE6_BRAFL	Ldh_1_C domain-containing protein. (138 aa)
	C3ZVK0_BRAFL	10-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. (909 aa)
	C3ZVI5_BRAFL	Carrier domain-containing protein; Belongs to the aldehyde dehydrogenase family. (936 aa)
	C3ZVC9_BRAFL	Aminotran_5 domain-containing protein. (456 aa)
	C3ZUZ8_BRAFL	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (326 aa)
	C3ZST8_BRAFL	Uncharacterized protein. (647 aa)
	C3ZSS9_BRAFL	Uncharacterized protein. (659 aa)
	C3ZRT2_BRAFL	Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (453 aa)
	C3ZPH6_BRAFL	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (330 aa)
	C3ZPF0_BRAFL	Uncharacterized protein. (672 aa)
	C3ZPE3_BRAFL	Uncharacterized protein. (569 aa)
	C3ZNU4_BRAFL	ZP domain-containing protein. (1020 aa)
	C3ZNT5_BRAFL	Malic enzyme. (594 aa)
	C3ZLK3_BRAFL	FAD-binding PCMH-type domain-containing protein. (455 aa)
	C3ZHC6_BRAFL	Uncharacterized protein. (433 aa)
	C3ZFK0_BRAFL	Uncharacterized protein. (629 aa)
	C3ZFJ1_BRAFL	Uncharacterized protein. (628 aa)
	C3ZFA4_BRAFL	ANK_REP_REGION domain-containing protein. (467 aa)
	C3ZCP5_BRAFL	Uncharacterized protein. (373 aa)
	C3ZCM2_BRAFL	DUF4392 domain-containing protein. (452 aa)

Your Current Organism:

Branchiostoma floridae

NCBI taxonomy Id: 7739
Other names: Amphioxus floridae, B. floridae, Florida lancelet

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C3XPB8_BRAFL	C3XSF7_BRAFL	C3XPB8	C3XSF7	Uncharacterized protein.	Glutaredoxin domain-containing protein.	0.739
C3XPB8_BRAFL	C3Y076_BRAFL	C3XPB8	C3Y076	Uncharacterized protein.	Uncharacterized protein.	0.982
C3XPB8_BRAFL	C3YIV5_BRAFL	C3XPB8	C3YIV5	Uncharacterized protein.	Aminotran_1_2 domain-containing protein.	0.841
C3XPB8_BRAFL	C3YJ03_BRAFL	C3XPB8	C3YJ03	Uncharacterized protein.	Uncharacterized protein.	0.417
C3XPB8_BRAFL	C3YMM1_BRAFL	C3XPB8	C3YMM1	Uncharacterized protein.	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).	0.998
C3XPB8_BRAFL	C3YNY7_BRAFL	C3XPB8	C3YNY7	Uncharacterized protein.	ATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.	0.512
C3XPB8_BRAFL	C3YQ59_BRAFL	C3XPB8	C3YQ59	Uncharacterized protein.	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	0.737
C3XPB8_BRAFL	C3YSJ9_BRAFL	C3XPB8	C3YSJ9	Uncharacterized protein.	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	0.737
C3XPB8_BRAFL	C3Z482_BRAFL	C3XPB8	C3Z482	Uncharacterized protein.	Malate dehydrogenase.	0.972
C3XPB8_BRAFL	C3Z4P9_BRAFL	C3XPB8	C3Z4P9	Uncharacterized protein.	Transket_pyr domain-containing protein.	0.476
C3XPB8_BRAFL	C3ZAU8_BRAFL	C3XPB8	C3ZAU8	Uncharacterized protein.	Uncharacterized protein.	0.707
C3XPB8_BRAFL	C3ZHC6_BRAFL	C3XPB8	C3ZHC6	Uncharacterized protein.	Uncharacterized protein.	0.739
C3XPB8_BRAFL	C3ZNT5_BRAFL	C3XPB8	C3ZNT5	Uncharacterized protein.	Malic enzyme.	0.992
C3XPB8_BRAFL	C3ZNU4_BRAFL	C3XPB8	C3ZNU4	Uncharacterized protein.	ZP domain-containing protein.	0.932
C3XPB8_BRAFL	C3ZXE6_BRAFL	C3XPB8	C3ZXE6	Uncharacterized protein.	Ldh_1_C domain-containing protein.	0.972
C3XPB8_BRAFL	C3ZZL9_BRAFL	C3XPB8	C3ZZL9	Uncharacterized protein.	Aspartate aminotransferase.	0.841
C3XPB8_BRAFL	C3ZZM4_BRAFL	C3XPB8	C3ZZM4	Uncharacterized protein.	Transket_pyr domain-containing protein.	0.476
C3XPB8_BRAFL	C3ZZM5_BRAFL	C3XPB8	C3ZZM5	Uncharacterized protein.	Uncharacterized protein.	0.476
C3XQA6_BRAFL	C3XUM8_BRAFL	C3XQA6	C3XUM8	Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	Glutamine amidotransferase type-2 domain-containing protein.	0.990
C3XQA6_BRAFL	C3Y076_BRAFL	C3XQA6	C3Y076	Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	Uncharacterized protein.	0.408