(83 nodes) Regulation of innate immune response network (Branchiostoma floridae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	C3ZBE1_BRAFL	Uncharacterized protein. (344 aa)
	C3ZBL6_BRAFL	Uncharacterized protein. (894 aa)
	C3ZBY7_BRAFL	Uncharacterized protein. (1553 aa)
	C3ZBY9_BRAFL	C2H2-type domain-containing protein. (1592 aa)
	C3ZBZ0_BRAFL	Uncharacterized protein. (1321 aa)
	C3ZBZ2_BRAFL	Uncharacterized protein. (1771 aa)
	C3ZE87_BRAFL	Protein kinase domain-containing protein. (659 aa)
	C3ZEI0_BRAFL	Uncharacterized protein. (246 aa)
	C3Y6H9_BRAFL	Poly [ADP-ribose] polymerase. (2209 aa)
	C3Y6H4_BRAFL	Poly [ADP-ribose] polymerase. (2120 aa)
	C3Y5X5_BRAFL	Poly [ADP-ribose] polymerase. (1925 aa)
	C3Y5P2_BRAFL	Poly [ADP-ribose] polymerase. (779 aa)
	C3Y5A9_BRAFL	zf-LYAR domain-containing protein. (352 aa)
	C3Y4S6_BRAFL	GH16 domain-containing protein. (483 aa)
	C3Y4B3_BRAFL	zf-LYAR domain-containing protein. (396 aa)
	C3Y406_BRAFL	Poly [ADP-ribose] polymerase. (2514 aa)
	C3Y3Q8_BRAFL	Uncharacterized protein. (1459 aa)
	C3Y3J3_BRAFL	Poly [ADP-ribose] polymerase. (652 aa)
	C3Y3J2_BRAFL	Poly [ADP-ribose] polymerase. (181 aa)
	C3XZK9_BRAFL	Uncharacterized protein. (580 aa)
	C4A0W8_BRAFL	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (504 aa)
	C3ZZM6_BRAFL	Uncharacterized protein. (197 aa)
	C3ZZ44_BRAFL	Uncharacterized protein. (63 aa)
	C3ZYU9_BRAFL	OTU domain-containing protein. (264 aa)
	C3ZYU8_BRAFL	Uncharacterized protein. (1550 aa)
	C3ZYU6_BRAFL	OTU domain-containing protein. (909 aa)
	C3ZYN0_BRAFL	Uncharacterized protein. (1246 aa)
	C3ZXZ8_BRAFL	Death domain-containing protein. (298 aa)
	C3ZX62_BRAFL	Uncharacterized protein. (240 aa)
	C3ZW21_BRAFL	Uncharacterized protein. (624 aa)
	C3ZUG9_BRAFL	Uncharacterized protein; Belongs to the ubiquitin-conjugating enzyme family. (201 aa)
	C3ZSQ6_BRAFL	RIO domain-containing protein. (470 aa)
	C3ZSM7_BRAFL	Ku domain-containing protein. (716 aa)
	C3ZS12_BRAFL	Uncharacterized protein. (970 aa)
	C3ZQZ9_BRAFL	Uncharacterized protein. (585 aa)
	C3ZPW8_BRAFL	Uncharacterized protein. (1470 aa)
	C3ZPV3_BRAFL	Uncharacterized protein. (1432 aa)
	C3ZPV2_BRAFL	Uncharacterized protein. (142 aa)
	C3ZNT2_BRAFL	Autophagy protein 5; Involved in autophagic vesicle formation. (261 aa)
	C3ZM34_BRAFL	Uncharacterized protein. (322 aa)
	C3ZJI8_BRAFL	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (86 aa)
	C3ZJD6_BRAFL	DC_STAMP domain-containing protein. (161 aa)
	C3ZJD5_BRAFL	DC_STAMP domain-containing protein. (101 aa)
	C3ZJD4_BRAFL	Uncharacterized protein. (436 aa)
	C3XZ97_BRAFL	Uncharacterized protein. (522 aa)
	C3XZ17_BRAFL	DNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family. (317 aa)
	C3XVG1_BRAFL	Uncharacterized protein. (1015 aa)
	C3XUV9_BRAFL	Uncharacterized protein. (165 aa)
	C3XUC4_BRAFL	Uncharacterized protein; Belongs to the peptidase C14A family. (399 aa)
	C3XU47_BRAFL	Uncharacterized protein. (300 aa)
	C3XTB5_BRAFL	Uncharacterized protein. (932 aa)
	C3XS07_BRAFL	Uncharacterized protein. (516 aa)
	C3XPG1_BRAFL	WW domain-containing protein. (284 aa)
	C3Z5Q3_BRAFL	Uncharacterized protein. (1287 aa)
	C3Z645_BRAFL	Uncharacterized protein. (63 aa)
	C3Z9W3_BRAFL	Cactin_mid domain-containing protein. (207 aa)
	C3Z4P8_BRAFL	Uncharacterized protein. (195 aa)
	C3Z2T5_BRAFL	Uncharacterized protein. (454 aa)
	C3Z261_BRAFL	Uncharacterized protein. (786 aa)
	C3Z260_BRAFL	Uncharacterized protein. (528 aa)
	C3Z1L4_BRAFL	NACHT domain-containing protein. (1135 aa)
	C3Z1F8_BRAFL	Ku domain-containing protein. (613 aa)
	C3Z0N9_BRAFL	Uncharacterized protein. (187 aa)
	C3YYC3_BRAFL	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1137 aa)
	C3YXE8_BRAFL	OTU domain-containing protein. (845 aa)
	C3YXD5_BRAFL	OTU domain-containing protein. (226 aa)
	C3YW57_BRAFL	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (504 aa)
	C3YSF6_BRAFL	Uncharacterized protein. (2447 aa)
	C3YS03_BRAFL	Uncharacterized protein. (2671 aa)
	C3YQF0_BRAFL	YTH domain-containing protein. (559 aa)
	C3YQA9_BRAFL	Uncharacterized protein. (198 aa)
	C3YQ95_BRAFL	Uncharacterized protein. (163 aa)
	C3YPU4_BRAFL	CCHC NOA-type domain-containing protein. (873 aa)
	C3YPS8_BRAFL	Uncharacterized protein. (712 aa)
	C3YMU6_BRAFL	Death domain-containing protein. (482 aa)
	C3YH63_BRAFL	Uncharacterized protein. (215 aa)
	C3YGW8_BRAFL	Uncharacterized protein. (340 aa)
	C3YFK4_BRAFL	Uncharacterized protein. (683 aa)
	C3YFD7_BRAFL	Uncharacterized protein; Belongs to the MT-A70-like family. (568 aa)
	C3YDJ4_BRAFL	RING-type domain-containing protein. (299 aa)
	C3YCU6_BRAFL	Uncharacterized protein. (667 aa)
	C3YCT4_BRAFL	Uncharacterized protein. (1589 aa)
	C3Y7A9_BRAFL	Protein kinase domain-containing protein. (739 aa)

Your Current Organism:

Branchiostoma floridae

NCBI taxonomy Id: 7739
Other names: Amphioxus floridae, B. floridae, Florida lancelet

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C3XS07_BRAFL	C3YDJ4_BRAFL	C3XS07	C3YDJ4	Uncharacterized protein.	RING-type domain-containing protein.	0.655
C3XUC4_BRAFL	C3YPS8_BRAFL	C3XUC4	C3YPS8	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein.	0.681
C3XVG1_BRAFL	C3YCU6_BRAFL	C3XVG1	C3YCU6	Uncharacterized protein.	Uncharacterized protein.	0.430
C3XVG1_BRAFL	C3ZBY7_BRAFL	C3XVG1	C3ZBY7	Uncharacterized protein.	Uncharacterized protein.	0.579
C3XVG1_BRAFL	C3ZBY9_BRAFL	C3XVG1	C3ZBY9	Uncharacterized protein.	C2H2-type domain-containing protein.	0.578
C3XVG1_BRAFL	C3ZBZ0_BRAFL	C3XVG1	C3ZBZ0	Uncharacterized protein.	Uncharacterized protein.	0.580
C3XVG1_BRAFL	C3ZBZ2_BRAFL	C3XVG1	C3ZBZ2	Uncharacterized protein.	Uncharacterized protein.	0.577
C3XZ17_BRAFL	C3YYC3_BRAFL	C3XZ17	C3YYC3	DNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.999
C3XZ17_BRAFL	C3Z5Q3_BRAFL	C3XZ17	C3Z5Q3	DNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.	Uncharacterized protein.	0.999
C3XZK9_BRAFL	C3ZQZ9_BRAFL	C3XZK9	C3ZQZ9	Uncharacterized protein.	Uncharacterized protein.	0.902
C3Y7A9_BRAFL	C3YPU4_BRAFL	C3Y7A9	C3YPU4	Protein kinase domain-containing protein.	CCHC NOA-type domain-containing protein.	0.946
C3Y7A9_BRAFL	C3YQ95_BRAFL	C3Y7A9	C3YQ95	Protein kinase domain-containing protein.	Uncharacterized protein.	0.791
C3Y7A9_BRAFL	C3YQA9_BRAFL	C3Y7A9	C3YQA9	Protein kinase domain-containing protein.	Uncharacterized protein.	0.791
C3YCU6_BRAFL	C3XVG1_BRAFL	C3YCU6	C3XVG1	Uncharacterized protein.	Uncharacterized protein.	0.430
C3YCU6_BRAFL	C3ZBY7_BRAFL	C3YCU6	C3ZBY7	Uncharacterized protein.	Uncharacterized protein.	0.430
C3YCU6_BRAFL	C3ZBY9_BRAFL	C3YCU6	C3ZBY9	Uncharacterized protein.	C2H2-type domain-containing protein.	0.430
C3YCU6_BRAFL	C3ZBZ0_BRAFL	C3YCU6	C3ZBZ0	Uncharacterized protein.	Uncharacterized protein.	0.430
C3YCU6_BRAFL	C3ZBZ2_BRAFL	C3YCU6	C3ZBZ2	Uncharacterized protein.	Uncharacterized protein.	0.430
C3YDJ4_BRAFL	C3XS07_BRAFL	C3YDJ4	C3XS07	RING-type domain-containing protein.	Uncharacterized protein.	0.655
C3YFD7_BRAFL	C3YQF0_BRAFL	C3YFD7	C3YQF0	Uncharacterized protein; Belongs to the MT-A70-like family.	YTH domain-containing protein.	0.688