(122 nodes) Positive regulation of cell cycle network (Branchiostoma floridae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	C3YCQ9_BRAFL	Uncharacterized protein. (545 aa)
	C3YBG7_BRAFL	RING-type domain-containing protein. (89 aa)
	C3YBE9_BRAFL	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1252 aa)
	C3YA17_BRAFL	DBF4-type domain-containing protein. (829 aa)
	C3Y9Y4_BRAFL	PDZ domain-containing protein. (324 aa)
	C3Y9K6_BRAFL	Uncharacterized protein. (846 aa)
	C3Y9A3_BRAFL	ATPase_AAA_core domain-containing protein. (2025 aa)
	C3Y946_BRAFL	Uncharacterized protein. (815 aa)
	C3Y945_BRAFL	Uncharacterized protein. (223 aa)
	C3Y7Q2_BRAFL	TPR_REGION domain-containing protein. (280 aa)
	C3Y719_BRAFL	Uncharacterized protein. (391 aa)
	C3Y6B5_BRAFL	Uncharacterized protein. (1548 aa)
	C3Y696_BRAFL	Uncharacterized protein. (304 aa)
	C3ZV28_BRAFL	Uncharacterized protein. (383 aa)
	C3ZV97_BRAFL	Endo/exonuclease/phosphatase domain-containing protein. (559 aa)
	C3ZXS7_BRAFL	TPR_REGION domain-containing protein. (273 aa)
	C4A079_BRAFL	R3H domain-containing protein. (58 aa)
	C4A0W8_BRAFL	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (504 aa)
	C4A0Y8_BRAFL	Uncharacterized protein. (907 aa)
	Msx	Muscle segment homeobox. (275 aa)
	C3Y1Y4_BRAFL	Death domain-containing protein. (561 aa)
	C3Y1S5_BRAFL	SMC_N domain-containing protein. (1096 aa)
	C3Y1F9_BRAFL	Uncharacterized protein. (1907 aa)
	C3Y136_BRAFL	Lactamase_B domain-containing protein. (202 aa)
	C3Y120_BRAFL	Uncharacterized protein. (82 aa)
	C3Y0R7_BRAFL	ANAPC5 domain-containing protein. (747 aa)
	C3Y0G7_BRAFL	Fork-head domain-containing protein. (402 aa)
	C3Y0B4_BRAFL	Uncharacterized protein. (180 aa)
	C3Y025_BRAFL	Cnd3 domain-containing protein. (1021 aa)
	C3XZ84_BRAFL	Uncharacterized protein. (380 aa)
	C3XVW8_BRAFL	RanBD1 domain-containing protein. (228 aa)
	C3XVD1_BRAFL	Uncharacterized protein. (3715 aa)
	C3XV95_BRAFL	Uncharacterized protein. (734 aa)
	C3XUK5_BRAFL	GFA domain-containing protein. (119 aa)
	C3XUJ5_BRAFL	ApaG domain-containing protein. (321 aa)
	C3XTY8_BRAFL	Uncharacterized protein. (581 aa)
	C3XSK0_BRAFL	CYCLIN domain-containing protein; Belongs to the cyclin family. (257 aa)
	C3XS09_BRAFL	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (427 aa)
	C3XRT2_BRAFL	Uncharacterized protein. (863 aa)
	C3XR20_BRAFL	Uncharacterized protein. (237 aa)
	C3XQ14_BRAFL	F-box domain-containing protein. (843 aa)
	C3XPW3_BRAFL	Uncharacterized protein. (484 aa)
	C3XPI0_BRAFL	Bin3-type SAM domain-containing protein. (192 aa)
	C3XPH9_BRAFL	Uncharacterized protein. (412 aa)
	C3YUV2_BRAFL	TPR_REGION domain-containing protein. (151 aa)
	C3YT48_BRAFL	Structural maintenance of chromosomes protein. (1229 aa)
	C3YT31_BRAFL	Uncharacterized protein. (293 aa)
	C3YRQ9_BRAFL	POLO box domain-containing protein. (158 aa)
	C3YQ27_BRAFL	Uncharacterized protein. (824 aa)
	C3YQ26_BRAFL	Uncharacterized protein. (150 aa)
	C3YNN9_BRAFL	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (82 aa)
	C3YN20_BRAFL	Uncharacterized protein. (687 aa)
	C3YMQ0_BRAFL	SP-RING-type domain-containing protein. (252 aa)
	C3YLS9_BRAFL	Uncharacterized protein. (325 aa)
	C3YLR9_BRAFL	Lactamase_B domain-containing protein. (205 aa)
	C3YL59_BRAFL	Mitogen-activated protein kinase. (321 aa)
	C3YKU4_BRAFL	Uncharacterized protein. (801 aa)
	C3YK31_BRAFL	Uncharacterized protein. (537 aa)
	C3YK10_BRAFL	SMC hinge domain-containing protein. (1155 aa)
	C3YJP8_BRAFL	Uncharacterized protein. (141 aa)
	C3YJI7_BRAFL	Uncharacterized protein. (923 aa)
	C3YVP4_BRAFL	Uncharacterized protein. (894 aa)
	C3YW57_BRAFL	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (504 aa)
	C3YXX5_BRAFL	Uncharacterized protein. (724 aa)
	C3YYK3_BRAFL	TPR_REGION domain-containing protein. (854 aa)
	C3YYS3_BRAFL	Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (598 aa)
	C3YZR1_BRAFL	Uncharacterized protein. (490 aa)
	C3YZU1_BRAFL	Uncharacterized protein. (500 aa)
	C3YZV2_BRAFL	WD_REPEATS_REGION domain-containing protein. (409 aa)
	C3Z0T9_BRAFL	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (857 aa)
	C3Z2E7_BRAFL	Muscle-specific homeobox-like protein. (307 aa)
	C3Z2S3_BRAFL	EGF-like domain-containing protein. (288 aa)
	C3Z3A4_BRAFL	Uncharacterized protein. (676 aa)
	C3Z3T3_BRAFL	Deacetylase sirtuin-type domain-containing protein. (325 aa)
	C3Z3T8_BRAFL	Uncharacterized protein; Belongs to the cyclin family. (751 aa)
	C3Z5Z2_BRAFL	HORMA domain-containing protein. (204 aa)
	C3Z792_BRAFL	Uncharacterized protein. (4526 aa)
	C3Z7Y7_BRAFL	TPR_REGION domain-containing protein. (318 aa)
	C3Z8A2_BRAFL	RB_A domain-containing protein. (305 aa)
	C3Z934_BRAFL	Uncharacterized protein. (123 aa)
	C3Z936_BRAFL	Uncharacterized protein. (365 aa)
	C3ZAJ1_BRAFL	Uncharacterized protein. (599 aa)
	C3ZCU0_BRAFL	Mitogen-activated protein kinase. (515 aa)
	C3ZDY2_BRAFL	CULLIN_2 domain-containing protein; Belongs to the cullin family. (753 aa)
	C3ZET4_BRAFL	PCI domain-containing protein. (383 aa)
	C3ZF00_BRAFL	Uncharacterized protein. (790 aa)
	C3YJB3_BRAFL	WD_REPEATS_REGION domain-containing protein. (595 aa)
	C3YH55_BRAFL	Uncharacterized protein. (579 aa)
	C3YGR2_BRAFL	Uncharacterized protein. (416 aa)
	C3YEG7_BRAFL	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (181 aa)
	C3YEF6_BRAFL	Cyclin N-terminal domain-containing protein. (244 aa)
	C3YDF6_BRAFL	ANK_REP_REGION domain-containing protein. (91 aa)
	C3ZF52_BRAFL	CULLIN_2 domain-containing protein; Belongs to the cullin family. (822 aa)
	C3ZG24_BRAFL	Uncharacterized protein. (536 aa)
	C3ZIB9_BRAFL	Uncharacterized protein. (191 aa)
	C3ZJB9_BRAFL	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (74 aa)
	C3ZKJ1_BRAFL	Uncharacterized protein. (718 aa)
	C3ZKM1_BRAFL	Protein kinase domain-containing protein. (535 aa)
	C3ZLP9_BRAFL	TPR_REGION domain-containing protein. (575 aa)
	C3ZLV7_BRAFL	PPP1R35_C domain-containing protein. (325 aa)
	C3ZMC2_BRAFL	Sm domain-containing protein. (130 aa)
	C3ZMU1_BRAFL	Uncharacterized protein. (1878 aa)
	C3ZMZ9_BRAFL	Uncharacterized protein. (749 aa)
	C3ZNF9_BRAFL	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (787 aa)
	C3ZNJ6_BRAFL	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (289 aa)
	C3ZQP5_BRAFL	Disintegrin domain-containing protein. (277 aa)
	C3ZQP6_BRAFL	Peptidase M12B domain-containing protein. (99 aa)
	C3ZR40_BRAFL	Uncharacterized protein. (262 aa)
	C3ZT85_BRAFL	HP domain-containing protein. (3977 aa)
	C3ZTM6_BRAFL	SWIM-type domain-containing protein. (1257 aa)
	C3ZUS4_BRAFL	RanBD1 domain-containing protein. (159 aa)
	C3ZV23_BRAFL	Uncharacterized protein. (224 aa)
	C3ZV25_BRAFL	Uncharacterized protein. (223 aa)
	C3YBW2_BRAFL	DBF4-type domain-containing protein. (1819 aa)
	C3Y5C7_BRAFL	Uncharacterized protein. (358 aa)
	C3Y4P7_BRAFL	Zpr1 domain-containing protein. (262 aa)
	C3Y4C7_BRAFL	Uncharacterized protein. (1023 aa)
	C3Y429_BRAFL	Uncharacterized protein. (1173 aa)
	C3Y2E5_BRAFL	E2F_TDP domain-containing protein. (159 aa)
	C3Y288_BRAFL	Uncharacterized protein. (366 aa)
	C3Y205_BRAFL	Uncharacterized protein. (454 aa)
	C3Y204_BRAFL	Uncharacterized protein. (596 aa)

Your Current Organism:

Branchiostoma floridae

NCBI taxonomy Id: 7739
Other names: Amphioxus floridae, B. floridae, Florida lancelet

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C3XPH9_BRAFL	C3XSK0_BRAFL	C3XPH9	C3XSK0	Uncharacterized protein.	CYCLIN domain-containing protein; Belongs to the cyclin family.	0.411
C3XPI0_BRAFL	C3XSK0_BRAFL	C3XPI0	C3XSK0	Bin3-type SAM domain-containing protein.	CYCLIN domain-containing protein; Belongs to the cyclin family.	0.411
C3XPW3_BRAFL	C3Z5Z2_BRAFL	C3XPW3	C3Z5Z2	Uncharacterized protein.	HORMA domain-containing protein.	0.638
C3XQ14_BRAFL	C3ZDY2_BRAFL	C3XQ14	C3ZDY2	F-box domain-containing protein.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.451
C3XQ14_BRAFL	C3ZV28_BRAFL	C3XQ14	C3ZV28	F-box domain-containing protein.	Uncharacterized protein.	0.521
C3XR20_BRAFL	C3Z5Z2_BRAFL	C3XR20	C3Z5Z2	Uncharacterized protein.	HORMA domain-containing protein.	0.932
C3XS09_BRAFL	C3Y025_BRAFL	C3XS09	C3Y025	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Cnd3 domain-containing protein.	0.542
C3XS09_BRAFL	C3Y696_BRAFL	C3XS09	C3Y696	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.454
C3XS09_BRAFL	C3Y9A3_BRAFL	C3XS09	C3Y9A3	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	ATPase_AAA_core domain-containing protein.	0.465
C3XS09_BRAFL	C3YA17_BRAFL	C3XS09	C3YA17	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	DBF4-type domain-containing protein.	0.523
C3XS09_BRAFL	C3YBW2_BRAFL	C3XS09	C3YBW2	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	DBF4-type domain-containing protein.	0.720
C3XS09_BRAFL	C3YDF6_BRAFL	C3XS09	C3YDF6	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	ANK_REP_REGION domain-containing protein.	0.832
C3XS09_BRAFL	C3YH55_BRAFL	C3XS09	C3YH55	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.403
C3XS09_BRAFL	C3YJI7_BRAFL	C3XS09	C3YJI7	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.417
C3XS09_BRAFL	C3YYS3_BRAFL	C3XS09	C3YYS3	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.	0.893
C3XS09_BRAFL	C3Z0T9_BRAFL	C3XS09	C3Z0T9	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.448
C3XS09_BRAFL	C3Z5Z2_BRAFL	C3XS09	C3Z5Z2	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	HORMA domain-containing protein.	0.736
C3XS09_BRAFL	C3ZDY2_BRAFL	C3XS09	C3ZDY2	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.472
C3XS09_BRAFL	C3ZF52_BRAFL	C3XS09	C3ZF52	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.546
C3XS09_BRAFL	C3ZKM1_BRAFL	C3XS09	C3ZKM1	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Protein kinase domain-containing protein.	0.811