(137 nodes) Negative regulation of proteolysis network (Branchiostoma floridae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	C3Z333_BRAFL	Uncharacterized protein. (1862 aa)
	C3XQ28_BRAFL	RING-type domain-containing protein. (545 aa)
	C3XQY8_BRAFL	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (189 aa)
	C3XR12_BRAFL	EGF-like domain-containing protein. (666 aa)
	C3XRE6_BRAFL	Uncharacterized protein. (1129 aa)
	C3XRK4_BRAFL	Uncharacterized protein. (197 aa)
	C3XRN1_BRAFL	Uncharacterized protein. (1244 aa)
	C3XRU7_BRAFL	Uncharacterized protein. (2383 aa)
	C3XSF4_BRAFL	Uncharacterized protein. (1251 aa)
	C3XU69_BRAFL	Uncharacterized protein. (1299 aa)
	C3XU79_BRAFL	Uncharacterized protein. (185 aa)
	C3XUC0_BRAFL	Uncharacterized protein. (906 aa)
	C3XUC2_BRAFL	Uncharacterized protein. (787 aa)
	C3XVR2_BRAFL	WD_REPEATS_REGION domain-containing protein. (353 aa)
	C3XVR3_BRAFL	WD_REPEATS_REGION domain-containing protein. (187 aa)
	C3XVS3_BRAFL	WD_REPEATS_REGION domain-containing protein. (200 aa)
	C3XVS4_BRAFL	WD_REPEATS_REGION domain-containing protein. (187 aa)
	C3XWE1_BRAFL	Uncharacterized protein. (973 aa)
	C3XX77_BRAFL	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (248 aa)
	C3XXM6_BRAFL	TPR_REGION domain-containing protein. (1022 aa)
	C3XYN9_BRAFL	Uncharacterized protein. (1020 aa)
	C3XYU0_BRAFL	Uncharacterized protein. (194 aa)
	C3XYV3_BRAFL	Uncharacterized protein. (95 aa)
	C3XYY5_BRAFL	Uncharacterized protein. (318 aa)
	C3XZL3_BRAFL	Uncharacterized protein. (4410 aa)
	C3XZL5_BRAFL	UBIQUITIN_CONJUGAT_2 domain-containing protein. (526 aa)
	C3XZS7_BRAFL	Uncharacterized protein. (183 aa)
	C3Y0H5_BRAFL	Uncharacterized protein. (355 aa)
	C3Y0Q3_BRAFL	Antistasin-like domain-containing protein. (558 aa)
	C3Y1V5_BRAFL	A2M_recep domain-containing protein. (625 aa)
	C3Y301_BRAFL	Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (197 aa)
	C3Y3X2_BRAFL	NTR domain-containing protein. (192 aa)
	Avp	Vasopressin-neurophysin protein. (167 aa)
	C3Y4R0_BRAFL	Uncharacterized protein; Belongs to the universal ribosomal protein uL5 family. (167 aa)
	C3Y6U5_BRAFL	Uncharacterized protein. (360 aa)
	C3Y7E8_BRAFL	Apple domain-containing protein. (535 aa)
	C3Y7M2_BRAFL	Uncharacterized protein; Belongs to the peptidase C19 family. (1318 aa)
	C3Y979_BRAFL	VWFA domain-containing protein. (152 aa)
	C3Y980_BRAFL	Uncharacterized protein. (388 aa)
	C3Y983_BRAFL	Uncharacterized protein. (642 aa)
	C3Y9D4_BRAFL	Uncharacterized protein. (550 aa)
	C3Y9Y4_BRAFL	PDZ domain-containing protein. (324 aa)
	C3YCD8_BRAFL	Uncharacterized protein. (375 aa)
	C3YEW7_BRAFL	Uncharacterized protein. (460 aa)
	C3YFK2_BRAFL	Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (278 aa)
	C3YFT4_BRAFL	Uncharacterized protein. (290 aa)
	C3YGH5_BRAFL	Uncharacterized protein. (111 aa)
	C3YGV0_BRAFL	SCP domain-containing protein; Belongs to the CRISP family. (187 aa)
	C3YHW8_BRAFL	FAD-binding PCMH-type domain-containing protein. (419 aa)
	C3YHY5_BRAFL	FAD-binding PCMH-type domain-containing protein. (379 aa)
	C3YIR6_BRAFL	Uncharacterized protein. (113 aa)
	C3YIU8_BRAFL	Uncharacterized protein. (848 aa)
	C3YJ44_BRAFL	Uncharacterized protein. (526 aa)
	C3YJ45_BRAFL	Uncharacterized protein. (259 aa)
	C3YKA5_BRAFL	UBIQUITIN_CONJUGAT_2 domain-containing protein. (306 aa)
	C3YKX9_BRAFL	Uncharacterized protein. (564 aa)
	C3YLB0_BRAFL	Nefa_Nip30_N domain-containing protein. (117 aa)
	C3YMZ2_BRAFL	WAP domain-containing protein. (294 aa)
	C3YPP8_BRAFL	BPTI/Kunitz inhibitor domain-containing protein. (55 aa)
	C3YPR2_BRAFL	Uncharacterized protein. (863 aa)
	C3YQ35_BRAFL	Uncharacterized protein. (936 aa)
	C3YQ36_BRAFL	Uncharacterized protein. (1154 aa)
	C3YQD5_BRAFL	Uncharacterized protein. (706 aa)
	C3YRA7_BRAFL	SCP domain-containing protein. (173 aa)
	C3YRM3_BRAFL	Methyltransf_FA domain-containing protein. (671 aa)
	C3YSZ9_BRAFL	FAD-binding PCMH-type domain-containing protein. (517 aa)
	C3YTI2_BRAFL	FAD-binding PCMH-type domain-containing protein. (517 aa)
	C3YTM4_BRAFL	Uncharacterized protein. (1202 aa)
	C3YTM5_BRAFL	SERPIN domain-containing protein; Belongs to the serpin family. (356 aa)
	C3YTM6_BRAFL	SERPIN domain-containing protein; Belongs to the serpin family. (377 aa)
	C3YTM8_BRAFL	SERPIN domain-containing protein; Belongs to the serpin family. (416 aa)
	C3YUQ1_BRAFL	BPTI/Kunitz inhibitor domain-containing protein. (53 aa)
	C3YVC7_BRAFL	CUB domain-containing protein. (427 aa)
	C3YWW3_BRAFL	Uncharacterized protein. (2425 aa)
	C3YY68_BRAFL	Methyltransf_FA domain-containing protein. (491 aa)
	C3Z1J2_BRAFL	BPTI/Kunitz inhibitor domain-containing protein. (58 aa)
	C3Z1J3_BRAFL	BPTI/Kunitz inhibitor domain-containing protein. (54 aa)
	C3Z2D9_BRAFL	SCP domain-containing protein. (183 aa)
	C3Z2T9_BRAFL	Uncharacterized protein. (179 aa)
	C3Z3B0_BRAFL	Uncharacterized protein. (866 aa)
	C3Z427_BRAFL	FYVE-type domain-containing protein. (325 aa)
	C3Z4R3_BRAFL	Uncharacterized protein. (272 aa)
	C3Z5N3_BRAFL	RING-type domain-containing protein. (358 aa)
	C3Z5V2_BRAFL	RING-type domain-containing protein. (395 aa)
	C3Z5V3_BRAFL	RING-type domain-containing protein. (376 aa)
	C3Z5V4_BRAFL	RING-type domain-containing protein. (371 aa)
	C3Z5X5_BRAFL	UDENN FNIP1/2-type domain-containing protein. (1126 aa)
	C3Z6Y3_BRAFL	UBIQUITIN_CONJUGAT_2 domain-containing protein. (1160 aa)
	C3Z7S6_BRAFL	Uncharacterized protein. (1276 aa)
	C3Z8L1_BRAFL	Uncharacterized protein. (224 aa)
	C3Z9G3_BRAFL	Ubiquitin-like domain-containing protein. (1268 aa)
	C3Z9S3_BRAFL	RING-type domain-containing protein. (370 aa)
	C3ZAA2_BRAFL	Bis(5'-adenosyl)-triphosphatase. (157 aa)
	C3ZAH8_BRAFL	Uncharacterized protein. (2208 aa)
	C3ZAI0_BRAFL	Uncharacterized protein. (206 aa)
	C3ZAI1_BRAFL	Uncharacterized protein. (181 aa)
	C3ZBE3_BRAFL	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (367 aa)
	C3ZCF8_BRAFL	SERPIN domain-containing protein; Belongs to the serpin family. (387 aa)
	C3ZCG2_BRAFL	SERPIN domain-containing protein; Belongs to the serpin family. (390 aa)
	C3ZDH2_BRAFL	RING-type domain-containing protein. (426 aa)
	C3ZDH3_BRAFL	RING-type domain-containing protein. (861 aa)
	C3ZE36_BRAFL	Uncharacterized protein. (258 aa)
	C3ZEN5_BRAFL	Uncharacterized protein. (730 aa)
	C3ZET4_BRAFL	PCI domain-containing protein. (383 aa)
	C3ZG27_BRAFL	Ubiquitin carboxyl-terminal hydrolase. (300 aa)
	C3ZIK2_BRAFL	TPR_REGION domain-containing protein. (184 aa)
	C3ZIM5_BRAFL	BPTI/Kunitz inhibitor domain-containing protein. (53 aa)
	C3ZIM7_BRAFL	SCP domain-containing protein. (186 aa)
	C3ZIM9_BRAFL	SCP domain-containing protein. (181 aa)
	C3ZIN8_BRAFL	Suppressor of fused protein-like protein. (375 aa)
	C3ZIQ7_BRAFL	Uncharacterized protein. (1238 aa)
	C3ZJQ8_BRAFL	RING-type domain-containing protein. (267 aa)
	C3ZJT9_BRAFL	Uncharacterized protein. (109 aa)
	C3ZM26_BRAFL	Cystatin domain-containing protein; Belongs to the cystatin family. (99 aa)
	C3ZN90_BRAFL	Uncharacterized protein. (285 aa)
	C3ZNI8_BRAFL	Uncharacterized protein. (297 aa)
	C3ZPE8_BRAFL	SCP domain-containing protein; Belongs to the CRISP family. (177 aa)
	C3ZPQ2_BRAFL	Uncharacterized protein. (343 aa)
	C3ZPX7_BRAFL	Uncharacterized protein; Belongs to the peptidase C19 family. (1046 aa)
	C3ZQ20_BRAFL	Uncharacterized protein. (62 aa)
	C3ZR37_BRAFL	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (306 aa)
	C3ZRI3_BRAFL	SCP domain-containing protein. (233 aa)
	C3ZTE1_BRAFL	SERPIN domain-containing protein; Belongs to the serpin family. (309 aa)
	C3ZVP8_BRAFL	Uncharacterized protein. (77 aa)
	C3ZWQ3_BRAFL	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (125 aa)
	C3ZWS9_BRAFL	EGF-like domain-containing protein. (710 aa)
	C3ZX54_BRAFL	Kazal-like domain-containing protein. (2243 aa)
	C3ZXK9_BRAFL	Uncharacterized protein. (246 aa)
	C3ZXL0_BRAFL	Protein kinase domain-containing protein. (96 aa)
	C3ZYP3_BRAFL	Uncharacterized protein. (1770 aa)
	C3ZYP4_BRAFL	TED_complement domain-containing protein. (84 aa)
	C3ZYP5_BRAFL	A2M_recep domain-containing protein. (437 aa)
	C3ZYY9_BRAFL	FCS-type domain-containing protein. (133 aa)
	C3ZYZ0_BRAFL	SAM domain-containing protein. (51 aa)
	C3ZZ31_BRAFL	Nuclear receptor domain-containing protein. (70 aa)
	Rab23b	Ubiquitin carboxyl-terminal hydrolase. (488 aa)
	C4A0H5_BRAFL	Uncharacterized protein. (966 aa)

Your Current Organism:

Branchiostoma floridae

NCBI taxonomy Id: 7739
Other names: Amphioxus floridae, B. floridae, Florida lancelet

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C3XQ28_BRAFL	C3Z5V2_BRAFL	C3XQ28	C3Z5V2	RING-type domain-containing protein.	RING-type domain-containing protein.	0.900
C3XQY8_BRAFL	C3YIR6_BRAFL	C3XQY8	C3YIR6	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	Uncharacterized protein.	0.795
C3XQY8_BRAFL	C3ZWQ3_BRAFL	C3XQY8	C3ZWQ3	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	0.900
C3XR12_BRAFL	C3XRU7_BRAFL	C3XR12	C3XRU7	EGF-like domain-containing protein.	Uncharacterized protein.	0.729
C3XR12_BRAFL	C3XSF4_BRAFL	C3XR12	C3XSF4	EGF-like domain-containing protein.	Uncharacterized protein.	0.400
C3XRE6_BRAFL	C3Z9G3_BRAFL	C3XRE6	C3Z9G3	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.877
C3XRU7_BRAFL	C3XR12_BRAFL	C3XRU7	C3XR12	Uncharacterized protein.	EGF-like domain-containing protein.	0.729
C3XRU7_BRAFL	C3ZIM5_BRAFL	C3XRU7	C3ZIM5	Uncharacterized protein.	BPTI/Kunitz inhibitor domain-containing protein.	0.729
C3XSF4_BRAFL	C3XR12_BRAFL	C3XSF4	C3XR12	Uncharacterized protein.	EGF-like domain-containing protein.	0.400
C3XSF4_BRAFL	C3ZIM5_BRAFL	C3XSF4	C3ZIM5	Uncharacterized protein.	BPTI/Kunitz inhibitor domain-containing protein.	0.400
C3XU79_BRAFL	C3Y4R0_BRAFL	C3XU79	C3Y4R0	Uncharacterized protein.	Uncharacterized protein; Belongs to the universal ribosomal protein uL5 family.	0.411
C3XUC2_BRAFL	C3Y1V5_BRAFL	C3XUC2	C3Y1V5	Uncharacterized protein.	A2M_recep domain-containing protein.	0.908
C3XUC2_BRAFL	C3ZYP5_BRAFL	C3XUC2	C3ZYP5	Uncharacterized protein.	A2M_recep domain-containing protein.	0.908
C3XVR2_BRAFL	C3XVR3_BRAFL	C3XVR2	C3XVR3	WD_REPEATS_REGION domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.915
C3XVR2_BRAFL	C3XVS4_BRAFL	C3XVR2	C3XVS4	WD_REPEATS_REGION domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.915
C3XVR3_BRAFL	C3XVR2_BRAFL	C3XVR3	C3XVR2	WD_REPEATS_REGION domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.915
C3XVR3_BRAFL	C3XVS3_BRAFL	C3XVR3	C3XVS3	WD_REPEATS_REGION domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.915
C3XVS3_BRAFL	C3XVR3_BRAFL	C3XVS3	C3XVR3	WD_REPEATS_REGION domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.915
C3XVS3_BRAFL	C3XVS4_BRAFL	C3XVS3	C3XVS4	WD_REPEATS_REGION domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.916
C3XVS4_BRAFL	C3XVR2_BRAFL	C3XVS4	C3XVR2	WD_REPEATS_REGION domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.915