(32 nodes) Negative regulation of epithelial cell proliferation network (Branchiostoma floridae)

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second shell of interactors

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proteins of unknown 3D structure

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Predicted Interactions

gene neighborhood

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Your Input:
	C3YW57_BRAFL	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (504 aa)
	C3YZC7_BRAFL	Uncharacterized protein. (164 aa)
	C3Z5H1_BRAFL	BHLH domain-containing protein. (238 aa)
	C3Z5I3_BRAFL	BHLH domain-containing protein. (238 aa)
	C3Z7E2_BRAFL	UDENN FLCN/SMCR8-type domain-containing protein. (473 aa)
	C3Z851_BRAFL	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (135 aa)
	C3Z8A2_BRAFL	RB_A domain-containing protein. (305 aa)
	C3ZB87_BRAFL	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (138 aa)
	C3ZE60_BRAFL	LIM domain-containing protein. (360 aa)
	C3ZB88_BRAFL	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (138 aa)
	C3ZC78_BRAFL	WD_REPEATS_REGION domain-containing protein. (222 aa)
	C3ZDJ4_BRAFL	WD_REPEATS_REGION domain-containing protein. (771 aa)
	C3ZE54_BRAFL	Uncharacterized protein. (2327 aa)
	C3ZE56_BRAFL	LIM zinc-binding domain-containing protein. (115 aa)
	C3YEQ8_BRAFL	Uncharacterized protein. (715 aa)
	C3YFA9_BRAFL	Uncharacterized protein. (1092 aa)
	C3YGW8_BRAFL	Uncharacterized protein. (340 aa)
	C3YKE8_BRAFL	Uncharacterized protein. (862 aa)
	C3YMZ1_BRAFL	RING-type domain-containing protein. (361 aa)
	C3YPX2_BRAFL	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (526 aa)
	C3Y8Z9_BRAFL	Uncharacterized protein. (470 aa)
	C3Y6U5_BRAFL	Uncharacterized protein. (360 aa)
	C3Y292_BRAFL	Uncharacterized protein. (440 aa)
	C3XZJ1_BRAFL	Uncharacterized protein. (409 aa)
	C3XZD3_BRAFL	Uncharacterized protein. (272 aa)
	C3XXX7_BRAFL	PID domain-containing protein. (128 aa)
	C3XXQ3_BRAFL	tRNA-binding domain-containing protein. (288 aa)
	C4A0W8_BRAFL	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (504 aa)
	C3ZV81_BRAFL	CRAL-TRIO domain-containing protein. (1389 aa)
	C3ZV77_BRAFL	Ras-GAP domain-containing protein. (1311 aa)
	C3ZG24_BRAFL	Uncharacterized protein. (536 aa)
	C3YUU6_BRAFL	Uncharacterized protein. (232 aa)

Your Current Organism:

Branchiostoma floridae

NCBI taxonomy Id: 7739
Other names: Amphioxus floridae, B. floridae, Florida lancelet

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C3XXX7_BRAFL	C3YUU6_BRAFL	C3XXX7	C3YUU6	PID domain-containing protein.	Uncharacterized protein.	0.443
C3Y292_BRAFL	C3ZC78_BRAFL	C3Y292	C3ZC78	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.416
C3Y292_BRAFL	C3ZDJ4_BRAFL	C3Y292	C3ZDJ4	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.993
C3YPX2_BRAFL	C3YW57_BRAFL	C3YPX2	C3YW57	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.818
C3YPX2_BRAFL	C4A0W8_BRAFL	C3YPX2	C4A0W8	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.818
C3YUU6_BRAFL	C3XXX7_BRAFL	C3YUU6	C3XXX7	Uncharacterized protein.	PID domain-containing protein.	0.443
C3YUU6_BRAFL	C3Z8A2_BRAFL	C3YUU6	C3Z8A2	Uncharacterized protein.	RB_A domain-containing protein.	0.803
C3YW57_BRAFL	C3YPX2_BRAFL	C3YW57	C3YPX2	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.818
C3YW57_BRAFL	C4A0W8_BRAFL	C3YW57	C4A0W8	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.543
C3Z851_BRAFL	C3ZB87_BRAFL	C3Z851	C3ZB87	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.904
C3Z851_BRAFL	C3ZB88_BRAFL	C3Z851	C3ZB88	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.904
C3Z8A2_BRAFL	C3YUU6_BRAFL	C3Z8A2	C3YUU6	RB_A domain-containing protein.	Uncharacterized protein.	0.803
C3ZB87_BRAFL	C3Z851_BRAFL	C3ZB87	C3Z851	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.904
C3ZB87_BRAFL	C3ZB88_BRAFL	C3ZB87	C3ZB88	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.900
C3ZB88_BRAFL	C3Z851_BRAFL	C3ZB88	C3Z851	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.904
C3ZB88_BRAFL	C3ZB87_BRAFL	C3ZB88	C3ZB87	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.900
C3ZC78_BRAFL	C3Y292_BRAFL	C3ZC78	C3Y292	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.416
C3ZDJ4_BRAFL	C3Y292_BRAFL	C3ZDJ4	C3Y292	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.993
C3ZV77_BRAFL	C3ZV81_BRAFL	C3ZV77	C3ZV81	Ras-GAP domain-containing protein.	CRAL-TRIO domain-containing protein.	0.951
C3ZV81_BRAFL	C3ZV77_BRAFL	C3ZV81	C3ZV77	CRAL-TRIO domain-containing protein.	Ras-GAP domain-containing protein.	0.951