(74 nodes) Regulation of protein secretion network (Branchiostoma floridae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	C3ZZ31_BRAFL	Nuclear receptor domain-containing protein. (70 aa)
	C3Z6K0_BRAFL	Uncharacterized protein. (269 aa)
	C3Z6L3_BRAFL	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (283 aa)
	C3Z6L4_BRAFL	G_PROTEIN_RECEP_F1_2 domain-containing protein. (104 aa)
	C3Z6P1_BRAFL	C1q domain-containing protein. (246 aa)
	C3Z7K7_BRAFL	C1q domain-containing protein. (220 aa)
	C3Z7S5_BRAFL	Uncharacterized protein. (1092 aa)
	C3Z8S5_BRAFL	Uncharacterized protein. (637 aa)
	C3Z977_BRAFL	C2 domain-containing protein. (143 aa)
	C3ZAE2_BRAFL	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (707 aa)
	C3ZGQ4_BRAFL	Cu2_monoox_C domain-containing protein. (435 aa)
	C3ZGU5_BRAFL	Uncharacterized protein. (317 aa)
	C3ZGW3_BRAFL	Uncharacterized protein. (287 aa)
	C3ZHI9_BRAFL	Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (142 aa)
	C3ZHT6_BRAFL	Uncharacterized protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (484 aa)
	C3ZJ85_BRAFL	Uncharacterized protein. (464 aa)
	Hsd11b1F	PDZ domain-containing protein. (199 aa)
	C3ZJT9_BRAFL	Uncharacterized protein. (109 aa)
	C3ZJX8_BRAFL	Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (138 aa)
	C3ZKL6_BRAFL	AMP-binding domain-containing protein. (305 aa)
	C3ZLI2_BRAFL	WD_REPEATS_REGION domain-containing protein. (1023 aa)
	C3ZPQ2_BRAFL	Uncharacterized protein. (343 aa)
	C3ZQ47_BRAFL	Nuclear receptor domain-containing protein. (70 aa)
	C3ZT96_BRAFL	Uncharacterized protein. (1672 aa)
	C3ZUF5_BRAFL	Sec3_C domain-containing protein. (777 aa)
	C3ZUF6_BRAFL	Sec3-PIP2_bind domain-containing protein. (758 aa)
	C3ZW37_BRAFL	Uncharacterized protein. (373 aa)
	C3ZW96_BRAFL	P/Homo B domain-containing protein; Belongs to the peptidase S8 family. (784 aa)
	C3ZWC6_BRAFL	Zn_dep_PLPC domain-containing protein. (823 aa)
	C3ZXH8_BRAFL	P/Homo B domain-containing protein; Belongs to the peptidase S8 family. (730 aa)
	C3Z6H4_BRAFL	Uncharacterized protein. (320 aa)
	C4A0W9_BRAFL	Uncharacterized protein. (179 aa)
	C3XY41_BRAFL	Ubiquitin-like domain-containing protein. (394 aa)
	C3XWJ2_BRAFL	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (252 aa)
	C3XVY8_BRAFL	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (414 aa)
	C3XS18_BRAFL	P/Homo B domain-containing protein; Belongs to the peptidase S8 family. (571 aa)
	C3Z3E1_BRAFL	J domain-containing protein. (138 aa)
	C3Z328_BRAFL	Uncharacterized protein. (287 aa)
	C3Z319_BRAFL	Uncharacterized protein. (118 aa)
	C3Z318_BRAFL	Uncharacterized protein. (128 aa)
	C3YZU1_BRAFL	Uncharacterized protein. (500 aa)
	C3YZC7_BRAFL	Uncharacterized protein. (164 aa)
	C3YZ86_BRAFL	Uncharacterized protein. (375 aa)
	RAB9A.1	Uncharacterized protein. (192 aa)
	C3YQ66_BRAFL	Uncharacterized protein. (520 aa)
	C3YMK9_BRAFL	Uncharacterized protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1679 aa)
	C3YLQ4_BRAFL	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (316 aa)
	C3YJ17_BRAFL	Uncharacterized protein. (735 aa)
	C3YJ16_BRAFL	Rhomboid domain-containing protein. (531 aa)
	C3YIU8_BRAFL	Uncharacterized protein. (848 aa)
	C3YIU7_BRAFL	Uncharacterized protein. (1125 aa)
	C3YI85_BRAFL	Uncharacterized protein. (596 aa)
	C3YCV9_BRAFL	Uncharacterized protein. (230 aa)
	C3YCU3_BRAFL	NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily. (302 aa)
	C3YBI5_BRAFL	3-hydroxy-3-methylglutaryl coenzyme A reductase. (876 aa)
	C3YB22_BRAFL	calpain_III domain-containing protein. (265 aa)
	C3YB16_BRAFL	Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (176 aa)
	C3YAV4_BRAFL	Uncharacterized protein. (122 aa)
	C3Y9K8_BRAFL	ANK_REP_REGION domain-containing protein. (133 aa)
	C3Y975_BRAFL	Uncharacterized protein. (395 aa)
	C3Y960_BRAFL	Rhomboid domain-containing protein. (1084 aa)
	C3Y771_BRAFL	G_PROTEIN_RECEP_F1_2 domain-containing protein. (388 aa)
	C3Y604_BRAFL	Uncharacterized protein. (448 aa)
	C3Y542_BRAFL	DUF4203 domain-containing protein. (513 aa)
	C3Y381_BRAFL	Elp3 domain-containing protein. (343 aa)
	C3Y212_BRAFL	Deacetylase sirtuin-type domain-containing protein. (414 aa)
	C3Y1T7_BRAFL	Uncharacterized protein. (81 aa)
	C3Y183_BRAFL	NR LBD domain-containing protein. (414 aa)
	C3Y145_BRAFL	Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (187 aa)
	C3XY56_BRAFL	Uncharacterized protein. (155 aa)
	C3Z502_BRAFL	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (434 aa)
	C3Z5Q5_BRAFL	Uncharacterized protein. (296 aa)
	C3Z6H1_BRAFL	Uncharacterized protein. (491 aa)
	C3Z6H2_BRAFL	NR LBD domain-containing protein. (121 aa)

Your Current Organism:

Branchiostoma floridae

NCBI taxonomy Id: 7739
Other names: Amphioxus floridae, B. floridae, Florida lancelet

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C3XVY8_BRAFL	C3ZAE2_BRAFL	C3XVY8	C3ZAE2	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.604
C3XY56_BRAFL	C3YAV4_BRAFL	C3XY56	C3YAV4	Uncharacterized protein.	Uncharacterized protein.	0.418
C3Y183_BRAFL	C3YIU7_BRAFL	C3Y183	C3YIU7	NR LBD domain-containing protein.	Uncharacterized protein.	0.443
C3Y183_BRAFL	C3Z6H1_BRAFL	C3Y183	C3Z6H1	NR LBD domain-containing protein.	Uncharacterized protein.	0.443
C3Y183_BRAFL	C3Z6H2_BRAFL	C3Y183	C3Z6H2	NR LBD domain-containing protein.	NR LBD domain-containing protein.	0.443
C3Y183_BRAFL	C3Z6H4_BRAFL	C3Y183	C3Z6H4	NR LBD domain-containing protein.	Uncharacterized protein.	0.443
C3Y212_BRAFL	C3YCU3_BRAFL	C3Y212	C3YCU3	Deacetylase sirtuin-type domain-containing protein.	NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily.	0.579
C3Y381_BRAFL	C3ZAE2_BRAFL	C3Y381	C3ZAE2	Elp3 domain-containing protein.	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.503
C3YAV4_BRAFL	C3XY56_BRAFL	C3YAV4	C3XY56	Uncharacterized protein.	Uncharacterized protein.	0.418
C3YCU3_BRAFL	C3Y212_BRAFL	C3YCU3	C3Y212	NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily.	Deacetylase sirtuin-type domain-containing protein.	0.579
C3YIU7_BRAFL	C3Y183_BRAFL	C3YIU7	C3Y183	Uncharacterized protein.	NR LBD domain-containing protein.	0.443
C3YQ66_BRAFL	C3ZGU5_BRAFL	C3YQ66	C3ZGU5	Uncharacterized protein.	Uncharacterized protein.	0.899
C3Z318_BRAFL	C3Z319_BRAFL	C3Z318	C3Z319	Uncharacterized protein.	Uncharacterized protein.	0.418
C3Z319_BRAFL	C3Z318_BRAFL	C3Z319	C3Z318	Uncharacterized protein.	Uncharacterized protein.	0.418
C3Z502_BRAFL	C3ZAE2_BRAFL	C3Z502	C3ZAE2	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.604
C3Z5Q5_BRAFL	C3Z8S5_BRAFL	C3Z5Q5	C3Z8S5	Uncharacterized protein.	Uncharacterized protein.	0.453
C3Z5Q5_BRAFL	C3ZKL6_BRAFL	C3Z5Q5	C3ZKL6	Uncharacterized protein.	AMP-binding domain-containing protein.	0.453
C3Z6H1_BRAFL	C3Y183_BRAFL	C3Z6H1	C3Y183	Uncharacterized protein.	NR LBD domain-containing protein.	0.443
C3Z6H2_BRAFL	C3Y183_BRAFL	C3Z6H2	C3Y183	NR LBD domain-containing protein.	NR LBD domain-containing protein.	0.443
C3Z6H4_BRAFL	C3Y183_BRAFL	C3Z6H4	C3Y183	Uncharacterized protein.	NR LBD domain-containing protein.	0.443