(83 nodes) Positive regulation of DNA-binding transcription factor activity network (Branchiostoma floridae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	C3YE52_BRAFL	Costars domain-containing protein. (155 aa)
	C3XPY9_BRAFL	Protein kinase domain-containing protein. (347 aa)
	C3XRE2_BRAFL	Non-specific serine/threonine protein kinase. (891 aa)
	C3XTJ3_BRAFL	TFIID_20kDa domain-containing protein. (184 aa)
	C3XTM4_BRAFL	RWD domain-containing protein. (237 aa)
	C3XU40_BRAFL	Uncharacterized protein. (2155 aa)
	C3XW02_BRAFL	Uncharacterized protein. (473 aa)
	C3XWH9_BRAFL	KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (226 aa)
	C3XYZ3_BRAFL	MADS-box domain-containing protein. (534 aa)
	C3XZ66_BRAFL	Proteasome subunit alpha type. (246 aa)
	C3XZJ1_BRAFL	Uncharacterized protein. (409 aa)
	C3XZR9_BRAFL	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (335 aa)
	C3Y1Z3_BRAFL	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (367 aa)
	C3Y272_BRAFL	Uncharacterized protein. (243 aa)
	C3Y293_BRAFL	MPN domain-containing protein. (168 aa)
	C3Y2Q3_BRAFL	Helicase ATP-binding domain-containing protein. (318 aa)
	C3Y332_BRAFL	Uncharacterized protein. (1237 aa)
	C3Y3W0_BRAFL	Uncharacterized protein. (678 aa)
	C3Y4P4_BRAFL	BTB domain-containing protein. (2239 aa)
	C3Y6Q4_BRAFL	Uncharacterized protein. (346 aa)
	C3Y7C4_BRAFL	Catalase domain-containing protein. (275 aa)
	C3Y7C5_BRAFL	Catalase domain-containing protein. (452 aa)
	C3Y7F3_BRAFL	Protein kinase domain-containing protein. (702 aa)
	C3Y8G6_BRAFL	Death domain-containing protein. (1064 aa)
	C3Y9A1_BRAFL	Uncharacterized protein. (144 aa)
	C3YCA2_BRAFL	Uncharacterized protein. (2573 aa)
	C3YCA3_BRAFL	Uncharacterized protein. (2077 aa)
	C3YCH6_BRAFL	Uncharacterized protein. (152 aa)
	C3YCH7_BRAFL	RING-type domain-containing protein. (350 aa)
	C3YCS5_BRAFL	Uncharacterized protein. (692 aa)
	C3YD77_BRAFL	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (425 aa)
	C3YD97_BRAFL	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (425 aa)
	Fusedb	Fused serine/threonine kinase-like protein; Belongs to the protein kinase superfamily. (255 aa)
	C3YE41_BRAFL	Costars domain-containing protein. (155 aa)
	C3YE67_BRAFL	Uncharacterized protein; Belongs to the tumor necrosis factor family. (180 aa)
	C3YFT5_BRAFL	Protein kinase domain-containing protein. (755 aa)
	C3YI94_BRAFL	Uncharacterized protein. (101 aa)
	C3YIR6_BRAFL	Uncharacterized protein. (113 aa)
	C3YJ83_BRAFL	RING-type domain-containing protein. (180 aa)
	C3YMK9_BRAFL	Uncharacterized protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1679 aa)
	C3YPI7_BRAFL	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (305 aa)
	C3YPX0_BRAFL	Uncharacterized protein. (477 aa)
	C3YPX1_BRAFL	TORC_N domain-containing protein. (123 aa)
	C3YTG3_BRAFL	Uncharacterized protein. (408 aa)
	C3YUP9_BRAFL	Protein kinase domain-containing protein. (925 aa)
	C3YV25_BRAFL	Uncharacterized protein. (498 aa)
	C3YXN4_BRAFL	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (157 aa)
	C3YXY3_BRAFL	Uncharacterized protein. (377 aa)
	C3Z1F1_BRAFL	Uncharacterized protein. (468 aa)
	C3Z1L4_BRAFL	NACHT domain-containing protein. (1135 aa)
	C3Z2M5_BRAFL	Uncharacterized protein. (2060 aa)
	C3Z804_BRAFL	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (970 aa)
	C3Z851_BRAFL	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (135 aa)
	C3Z8U0_BRAFL	Uncharacterized protein. (572 aa)
	C3ZB87_BRAFL	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (138 aa)
	C3ZB88_BRAFL	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (138 aa)
	C3ZDW2_BRAFL	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (374 aa)
	C3ZDW4_BRAFL	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (288 aa)
	C3ZDW5_BRAFL	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (412 aa)
	C3ZDW6_BRAFL	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (412 aa)
	C3ZDW7_BRAFL	CTCK domain-containing protein. (140 aa)
	C3ZG31_BRAFL	Uncharacterized protein. (474 aa)
	C3ZG34_BRAFL	Uncharacterized protein. (552 aa)
	C3ZG35_BRAFL	Uncharacterized protein. (658 aa)
	C3ZG37_BRAFL	Uncharacterized protein. (631 aa)
	C3ZG38_BRAFL	MATH domain-containing protein. (373 aa)
	C3ZG39_BRAFL	Uncharacterized protein. (549 aa)
	C3ZG40_BRAFL	Uncharacterized protein. (503 aa)
	C3ZG42_BRAFL	Uncharacterized protein. (482 aa)
	C3ZH16_BRAFL	Uncharacterized protein. (473 aa)
	C3ZLG8_BRAFL	Uncharacterized protein. (213 aa)
	C3ZLH8_BRAFL	Probable lysine-specific histone demethylase 1; Probable histone demethylase that specifically demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Demethylates both mono- and di-methylated 'Lys-4' of histone H3. (804 aa)
	C3ZN65_BRAFL	Uncharacterized protein. (147 aa)
	C3ZPZ7_BRAFL	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (451 aa)
	C3ZTK7_BRAFL	ARID domain-containing protein. (1000 aa)
	C3ZTW1_BRAFL	Smoothend-like protein protein; Belongs to the G-protein coupled receptor Fz/Smo family. (1250 aa)
	C3ZUG6_BRAFL	Uncharacterized protein. (3563 aa)
	C3ZVQ6_BRAFL	Uncharacterized protein. (439 aa)
	C3ZVQ7_BRAFL	AGC-kinase C-terminal domain-containing protein. (104 aa)
	C3ZXG1_BRAFL	Uncharacterized protein. (122 aa)
	C3ZXI3_BRAFL	TAZ-type domain-containing protein. (131 aa)
	C3ZYU7_BRAFL	MATH domain-containing protein. (107 aa)
	C4A0X2_BRAFL	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (481 aa)

Your Current Organism:

Branchiostoma floridae

NCBI taxonomy Id: 7739
Other names: Amphioxus floridae, B. floridae, Florida lancelet

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C3XU40_BRAFL	C3Y8G6_BRAFL	C3XU40	C3Y8G6	Uncharacterized protein.	Death domain-containing protein.	0.813
C3XU40_BRAFL	C3YFT5_BRAFL	C3XU40	C3YFT5	Uncharacterized protein.	Protein kinase domain-containing protein.	0.608
C3XU40_BRAFL	C3YV25_BRAFL	C3XU40	C3YV25	Uncharacterized protein.	Uncharacterized protein.	0.999
C3XU40_BRAFL	C3ZXG1_BRAFL	C3XU40	C3ZXG1	Uncharacterized protein.	Uncharacterized protein.	0.608
C3XW02_BRAFL	C3YPX1_BRAFL	C3XW02	C3YPX1	Uncharacterized protein.	TORC_N domain-containing protein.	0.660
C3XWH9_BRAFL	C3Y293_BRAFL	C3XWH9	C3Y293	KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family.	MPN domain-containing protein.	0.585
C3XZ66_BRAFL	C3Y293_BRAFL	C3XZ66	C3Y293	Proteasome subunit alpha type.	MPN domain-containing protein.	0.576
C3XZ66_BRAFL	C3YCS5_BRAFL	C3XZ66	C3YCS5	Proteasome subunit alpha type.	Uncharacterized protein.	0.502
C3XZR9_BRAFL	C3YFT5_BRAFL	C3XZR9	C3YFT5	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Protein kinase domain-containing protein.	0.464
C3XZR9_BRAFL	C3YI94_BRAFL	C3XZR9	C3YI94	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.484
C3XZR9_BRAFL	C3YJ83_BRAFL	C3XZR9	C3YJ83	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	RING-type domain-containing protein.	0.484
C3XZR9_BRAFL	C3ZH16_BRAFL	C3XZR9	C3ZH16	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.431
C3XZR9_BRAFL	C3ZN65_BRAFL	C3XZR9	C3ZN65	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.484
C3Y293_BRAFL	C3XWH9_BRAFL	C3Y293	C3XWH9	MPN domain-containing protein.	KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family.	0.585
C3Y293_BRAFL	C3XZ66_BRAFL	C3Y293	C3XZ66	MPN domain-containing protein.	Proteasome subunit alpha type.	0.576
C3Y293_BRAFL	C3Y6Q4_BRAFL	C3Y293	C3Y6Q4	MPN domain-containing protein.	Uncharacterized protein.	0.579
C3Y2Q3_BRAFL	C3Y3W0_BRAFL	C3Y2Q3	C3Y3W0	Helicase ATP-binding domain-containing protein.	Uncharacterized protein.	0.483
C3Y2Q3_BRAFL	C3Y9A1_BRAFL	C3Y2Q3	C3Y9A1	Helicase ATP-binding domain-containing protein.	Uncharacterized protein.	0.874
C3Y332_BRAFL	C3Y9A1_BRAFL	C3Y332	C3Y9A1	Uncharacterized protein.	Uncharacterized protein.	0.496
C3Y332_BRAFL	C3YCA2_BRAFL	C3Y332	C3YCA2	Uncharacterized protein.	Uncharacterized protein.	0.500