(129 nodes) Meiotic cell cycle network (Branchiostoma floridae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	C3XZ75_BRAFL	Protein kinase domain-containing protein. (105 aa)
	C3ZHD8_BRAFL	Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. (460 aa)
	C3ZEN4_BRAFL	Mre11_DNA_bind domain-containing protein. (441 aa)
	C3ZE96_BRAFL	Gamma-tubulin complex component. (912 aa)
	C3ZC15_BRAFL	Uncharacterized protein. (260 aa)
	C3ZC14_BRAFL	KIND domain-containing protein. (209 aa)
	C3ZBU1_BRAFL	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (412 aa)
	C3ZB98_BRAFL	Protein kinase domain-containing protein. (235 aa)
	C3ZAT8_BRAFL	KIND domain-containing protein. (852 aa)
	C3ZA80_BRAFL	Uncharacterized protein. (1140 aa)
	C3Z9V4_BRAFL	Protein kinase domain-containing protein. (242 aa)
	C3Z9U6_BRAFL	Protein kinase domain-containing protein. (214 aa)
	C3Z9G3_BRAFL	Ubiquitin-like domain-containing protein. (1268 aa)
	C3Z9D8_BRAFL	Peptidylprolyl isomerase. (311 aa)
	C3Z6W7_BRAFL	ERCC4 domain-containing protein. (598 aa)
	C3Z5S8_BRAFL	Uncharacterized protein; Belongs to the argonaute family. (734 aa)
	C3Z501_BRAFL	Protein kinase domain-containing protein. (160 aa)
	C3Z500_BRAFL	Protein kinase domain-containing protein. (136 aa)
	C3Z2U5_BRAFL	Gamma-tubulin complex component. (462 aa)
	C3Z2H0_BRAFL	Cnd1 domain-containing protein. (1141 aa)
	C3Z277_BRAFL	HMG box domain-containing protein. (490 aa)
	C3Z1V1_BRAFL	DNA_MISMATCH_REPAIR_2 domain-containing protein. (774 aa)
	C3YZR1_BRAFL	Uncharacterized protein. (490 aa)
	C3YYJ6_BRAFL	TOP4c domain-containing protein. (1181 aa)
	C3YX60_BRAFL	Uncharacterized protein. (358 aa)
	C3YWA5_BRAFL	AAA_23 domain-containing protein. (187 aa)
	C3YW44_BRAFL	Protein kinase domain-containing protein. (132 aa)
	C3YVY6_BRAFL	RECA_2 domain-containing protein. (103 aa)
	C3YV52_BRAFL	Meiotic nuclear division protein 1 homolog; Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. Belongs to the MND1 family. (205 aa)
	C3YUH0_BRAFL	Protein kinase domain-containing protein. (132 aa)
	C3YUB8_BRAFL	Protein kinase domain-containing protein. (219 aa)
	C3YT48_BRAFL	Structural maintenance of chromosomes protein. (1229 aa)
	C3YQP3_BRAFL	Uncharacterized protein. (215 aa)
	C3YQP1_BRAFL	MutS_IV domain-containing protein. (210 aa)
	C3YQ87_BRAFL	Uncharacterized protein. (1290 aa)
	C3YQ02_BRAFL	LEM domain-containing protein. (1888 aa)
	C3YPI5_BRAFL	Uncharacterized protein. (634 aa)
	C3YNI7_BRAFL	Uncharacterized protein. (1175 aa)
	C3YK10_BRAFL	SMC hinge domain-containing protein. (1155 aa)
	C3YI58_BRAFL	TPR_REGION domain-containing protein. (720 aa)
	C3YI56_BRAFL	Uncharacterized protein. (162 aa)
	C3YI31_BRAFL	DUF1767 domain-containing protein. (184 aa)
	C3YH73_BRAFL	FAT domain-containing protein. (2357 aa)
	C3YH71_BRAFL	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (553 aa)
	C3YFI7_BRAFL	AAA domain-containing protein; Belongs to the AAA ATPase family. (409 aa)
	C3YFG1_BRAFL	FHA domain-containing protein. (721 aa)
	C3YFB0_BRAFL	RING-type domain-containing protein. (304 aa)
	C3YDQ7_BRAFL	Uncharacterized protein. (499 aa)
	C3YDJ3_BRAFL	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (495 aa)
	C3YBF1_BRAFL	Gamma-tubulin complex component. (171 aa)
	C3YBE7_BRAFL	Uncharacterized protein. (1105 aa)
	C3YAZ8_BRAFL	SEC63 domain-containing protein. (466 aa)
	C3YA66_BRAFL	Uncharacterized protein. (348 aa)
	C3Y953_BRAFL	SUN domain-containing protein. (1111 aa)
	C3Y937_BRAFL	Uncharacterized protein. (427 aa)
	C3Y909_BRAFL	Deacetylase sirtuin-type domain-containing protein. (399 aa)
	C3Y7Z7_BRAFL	Checkpoint protein; Belongs to the HUS1 family. (280 aa)
	C3Y7Y2_BRAFL	Peptidase C50 domain-containing protein. (2958 aa)
	C3Y7L2_BRAFL	INCENP_ARK-bind domain-containing protein. (1201 aa)
	C3Y7J4_BRAFL	HORMA domain-containing protein. (202 aa)
	C3Y6L7_BRAFL	Protein kinase domain-containing protein. (409 aa)
	C3Y6J8_BRAFL	Uncharacterized protein. (156 aa)
	C3Y697_BRAFL	Uncharacterized protein. (557 aa)
	C3Y5S4_BRAFL	Uncharacterized protein. (334 aa)
	C3Y5L4_BRAFL	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (585 aa)
	C3Y4H9_BRAFL	RRM domain-containing protein. (413 aa)
	C3Y4H8_BRAFL	RRM domain-containing protein. (447 aa)
	C3Y4B5_BRAFL	TACC_C domain-containing protein. (1514 aa)
	C3Y458_BRAFL	DNA_mis_repair domain-containing protein. (717 aa)
	C3Y1F9_BRAFL	Uncharacterized protein. (1907 aa)
	C3Y192_BRAFL	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (310 aa)
	C3Y120_BRAFL	Uncharacterized protein. (82 aa)
	C3Y0V9_BRAFL	Uncharacterized protein. (343 aa)
	C3Y0V8_BRAFL	ERCC4 domain-containing protein. (600 aa)
	C3Y0V4_BRAFL	ERCC4 domain-containing protein. (268 aa)
	C3Y0B6_BRAFL	Uncharacterized protein. (337 aa)
	C3Y0B4_BRAFL	Uncharacterized protein. (180 aa)
	C3XZ76_BRAFL	Protein kinase domain-containing protein. (133 aa)
	C3XYZ6_BRAFL	BUB1 N-terminal domain-containing protein. (234 aa)
	C3XYZ5_BRAFL	Protein kinase domain-containing protein. (211 aa)
	C3XYZ4_BRAFL	Uncharacterized protein. (1475 aa)
	C3XVN7_BRAFL	Protein kinase domain-containing protein. (339 aa)
	C3XV97_BRAFL	Uncharacterized protein. (278 aa)
	C3XV62_BRAFL	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (403 aa)
	C3XV32_BRAFL	Uncharacterized protein. (457 aa)
	C3XV23_BRAFL	Piwi domain-containing protein. (323 aa)
	C3XV22_BRAFL	Uncharacterized protein. (3194 aa)
	C3XV20_BRAFL	Uncharacterized protein; Belongs to the argonaute family. (857 aa)
	C3XUE7_BRAFL	Uncharacterized protein. (2299 aa)
	C3XTZ1_BRAFL	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (275 aa)
	C3XSY1_BRAFL	Tudor domain-containing protein. (957 aa)
	C3XSQ6_BRAFL	Uncharacterized protein. (196 aa)
	C3XS56_BRAFL	SMP-LTD domain-containing protein. (436 aa)
	C3XS16_BRAFL	Uncharacterized protein. (107 aa)
	C3XRP0_BRAFL	Uncharacterized protein. (2342 aa)
	C3XR93_BRAFL	DNA_mis_repair domain-containing protein. (362 aa)
	C3XPU5_BRAFL	ERCC4 domain-containing protein. (1825 aa)
	C3XPS2_BRAFL	Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. (1451 aa)
	C3XPH5_BRAFL	Uncharacterized protein. (501 aa)
	C3ZHE3_BRAFL	Uncharacterized protein. (212 aa)
	C3ZHV8_BRAFL	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (265 aa)
	C3ZHV9_BRAFL	Uncharacterized protein. (256 aa)
	C3ZI53_BRAFL	Cor1 domain-containing protein. (1524 aa)
	C3ZIC2_BRAFL	Fork-head domain-containing protein. (86 aa)
	C3ZJ92_BRAFL	Uncharacterized protein. (185 aa)
	C3ZJT9_BRAFL	Uncharacterized protein. (109 aa)
	C3ZKW1_BRAFL	Uncharacterized protein; Belongs to the argonaute family. (755 aa)
	C3ZM03_BRAFL	Cor1 domain-containing protein. (242 aa)
	C3ZMX5_BRAFL	Uncharacterized protein. (1057 aa)
	C3ZMY4_BRAFL	Uncharacterized protein. (774 aa)
	C3ZMZ9_BRAFL	Uncharacterized protein. (749 aa)
	C3ZNW9_BRAFL	ERCC4 domain-containing protein. (515 aa)
	C3ZNX8_BRAFL	Uncharacterized protein. (233 aa)
	C3ZP69_BRAFL	Uncharacterized protein. (650 aa)
	C3ZPX6_BRAFL	Gamma-tubulin complex component. (1089 aa)
	C3ZPX9_BRAFL	PCI domain-containing protein. (377 aa)
	C3ZQF6_BRAFL	Protein kinase domain-containing protein. (332 aa)
	C3ZR70_BRAFL	Uncharacterized protein. (379 aa)
	C3ZRQ6_BRAFL	RING-type domain-containing protein. (178 aa)
	C3ZTM6_BRAFL	SWIM-type domain-containing protein. (1257 aa)
	C3ZUC0_BRAFL	Gamma-tubulin complex component. (313 aa)
	C3ZUC1_BRAFL	Uncharacterized protein. (1036 aa)
	C3ZUN4_BRAFL	CCHC-type domain-containing protein. (583 aa)
	C3ZXI2_BRAFL	Protein kinase domain-containing protein. (131 aa)
	C3ZXK6_BRAFL	Protein kinase domain-containing protein. (173 aa)
	C3ZY88_BRAFL	F-box domain-containing protein. (1107 aa)
	C3ZYG0_BRAFL	G_PROTEIN_RECEP_F1_2 domain-containing protein. (1765 aa)
	C4A079_BRAFL	R3H domain-containing protein. (58 aa)
	C4A088_BRAFL	BTB domain-containing protein. (2428 aa)

Your Current Organism:

Branchiostoma floridae

NCBI taxonomy Id: 7739
Other names: Amphioxus floridae, B. floridae, Florida lancelet

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C3XPS2_BRAFL	C3XYZ5_BRAFL	C3XPS2	C3XYZ5	Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.	Protein kinase domain-containing protein.	0.455
C3XPS2_BRAFL	C3XYZ6_BRAFL	C3XPS2	C3XYZ6	Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.	BUB1 N-terminal domain-containing protein.	0.437
C3XPS2_BRAFL	C3Y697_BRAFL	C3XPS2	C3Y697	Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.	Uncharacterized protein.	0.779
C3XPS2_BRAFL	C3Y7L2_BRAFL	C3XPS2	C3Y7L2	Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.	INCENP_ARK-bind domain-containing protein.	0.560
C3XPS2_BRAFL	C3Y7Y2_BRAFL	C3XPS2	C3Y7Y2	Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.	Peptidase C50 domain-containing protein.	0.674
C3XPS2_BRAFL	C3YK10_BRAFL	C3XPS2	C3YK10	Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.	SMC hinge domain-containing protein.	0.999
C3XPS2_BRAFL	C3YT48_BRAFL	C3XPS2	C3YT48	Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.	Structural maintenance of chromosomes protein.	0.999
C3XPS2_BRAFL	C3YYJ6_BRAFL	C3XPS2	C3YYJ6	Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.	TOP4c domain-containing protein.	0.609
C3XPS2_BRAFL	C3Z2H0_BRAFL	C3XPS2	C3Z2H0	Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.	Cnd1 domain-containing protein.	0.751
C3XPS2_BRAFL	C3ZJT9_BRAFL	C3XPS2	C3ZJT9	Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.	Uncharacterized protein.	0.430
C3XPS2_BRAFL	C3ZTM6_BRAFL	C3XPS2	C3ZTM6	Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.	SWIM-type domain-containing protein.	0.999
C3XPU5_BRAFL	C3XRP0_BRAFL	C3XPU5	C3XRP0	ERCC4 domain-containing protein.	Uncharacterized protein.	0.964
C3XPU5_BRAFL	C3Y0V4_BRAFL	C3XPU5	C3Y0V4	ERCC4 domain-containing protein.	ERCC4 domain-containing protein.	0.540
C3XPU5_BRAFL	C3Y0V8_BRAFL	C3XPU5	C3Y0V8	ERCC4 domain-containing protein.	ERCC4 domain-containing protein.	0.540
C3XPU5_BRAFL	C3Y0V9_BRAFL	C3XPU5	C3Y0V9	ERCC4 domain-containing protein.	Uncharacterized protein.	0.540
C3XPU5_BRAFL	C3Y937_BRAFL	C3XPU5	C3Y937	ERCC4 domain-containing protein.	Uncharacterized protein.	0.797
C3XPU5_BRAFL	C3YFG1_BRAFL	C3XPU5	C3YFG1	ERCC4 domain-containing protein.	FHA domain-containing protein.	0.443
C3XPU5_BRAFL	C3YH71_BRAFL	C3XPU5	C3YH71	ERCC4 domain-containing protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.402
C3XPU5_BRAFL	C3YH73_BRAFL	C3XPU5	C3YH73	ERCC4 domain-containing protein.	FAT domain-containing protein.	0.402
C3XPU5_BRAFL	C3YI31_BRAFL	C3XPU5	C3YI31	ERCC4 domain-containing protein.	DUF1767 domain-containing protein.	0.661